FISH RET Gene 10q11.2 Rearrangement Test
Comprehensive Genetic Analysis for Cancer Detection
The FISH RET Gene 10q11.2 Rearrangement Test represents a cutting-edge molecular diagnostic approach for detecting specific genetic abnormalities associated with various cancers. This sophisticated cytogenetic analysis focuses on the RET proto-oncogene located at chromosome 10q11.2, a critical genetic region implicated in multiple cancer types including thyroid cancer, lung adenocarcinoma, and other malignancies.
What Does This Test Measure?
This specialized FISH test specifically detects:
- RET gene rearrangements and fusions
- Chromosomal translocations involving the RET locus
- Gene amplification events affecting RET
- Structural abnormalities at chromosome 10q11.2
- Oncogenic fusion partners with RET
Who Should Consider This Test?
This genetic analysis is recommended for individuals with:
- Suspected or confirmed thyroid cancer, particularly medullary thyroid carcinoma
- Non-small cell lung cancer, especially adenocarcinoma subtypes
- Family history of multiple endocrine neoplasia type 2 (MEN2)
- Patients with treatment-resistant cancers seeking targeted therapy options
- Individuals with unexplained cancer syndromes involving endocrine tissues
- Patients requiring comprehensive molecular profiling for precision oncology
Clinical Benefits and Applications
The FISH RET Gene Rearrangement Test offers numerous clinical advantages:
- Precision Treatment Guidance: Identifies patients eligible for RET-targeted therapies
- Early Detection: Enables early intervention in high-risk individuals
- Family Risk Assessment: Provides crucial information for genetic counseling
- Therapeutic Monitoring: Helps track treatment response and resistance development
- Comprehensive Cancer Profiling: Complements other molecular tests for complete genetic characterization
Understanding Your Test Results
Your FISH RET Gene analysis results will provide critical information about:
- Positive Result: Indicates presence of RET gene rearrangement, suggesting eligibility for targeted RET inhibitors
- Negative Result: No RET rearrangement detected, guiding alternative treatment approaches
- Inconclusive Result: May require additional testing or sample re-evaluation
- Variant Interpretation: Detailed analysis of specific RET alterations and their clinical significance
Test Specifications and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | FISH RET Gene 10q11.2 Rearrangement Test |
| Discount Price | $262 USD |
| Regular Price | $426 USD |
| Turnaround Time | Sample Daily by 4 pm; Report 4 Working days |
| Sample Type | Formalin fixed paraffin embedded tissue block with 10% tumor tissue |
| Specialty | Oncology, Cancer Genetics |
| Method | Fluorescence In Situ Hybridization (FISH) |
Sample Requirements and Preparation
For accurate testing, please ensure:
- Submit Formalin fixed paraffin embedded tissue block
- Ship samples at room temperature
- Tissue block must contain minimum 10% tumor tissue
- Complete Chromosome & FISH analysis Requisition Form (Form 17)
- Proper clinical documentation and patient history
Nationwide Testing Availability
GGC DNA provides comprehensive genetic testing services across the United States with branches in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more locations. Our nationwide network ensures accessible, reliable genetic testing for patients and healthcare providers throughout the country.
Take Action for Your Health
Don’t wait to get the critical genetic information you need for informed cancer management. Our expert team is ready to assist you with comprehensive genetic analysis and personalized guidance. Contact us today to schedule your FISH RET Gene Rearrangement Test and take the first step toward precision cancer care.
Call or WhatsApp: +1(267) 388-9828
Book Your Test Today for Only $262 USD
