FISH Ewing Sarcoma EWS 22q12 EWSR1 Rearrangement Test
Understanding Ewing Sarcoma Genetic Testing
The FISH Ewing Sarcoma EWS 22q12 EWSR1 Rearrangement Test represents a cutting-edge molecular diagnostic approach for detecting specific genetic abnormalities associated with Ewing sarcoma tumors. This sophisticated testing methodology plays a crucial role in modern oncology by providing definitive genetic evidence for accurate diagnosis and treatment planning.
What This Test Measures and Detects
This specialized FISH test specifically identifies chromosomal rearrangements involving the EWSR1 gene located on chromosome 22 at position 22q12. The test detects:
- Translocation events between EWSR1 and partner genes
- Specific gene fusions characteristic of Ewing sarcoma family tumors
- Chromosomal breakpoints and rearrangement patterns
- Genetic markers that differentiate Ewing sarcoma from other similar cancers
Who Should Consider This Test
This genetic test is recommended for individuals presenting with:
- Unexplained bone pain or tenderness
- Suspicious soft tissue masses or tumors
- Radiographic findings suggestive of bone tumors
- Clinical symptoms consistent with Ewing sarcoma
- Patients requiring differential diagnosis between Ewing sarcoma and other small round blue cell tumors
Clinical Indications and Symptoms
Patients experiencing persistent localized pain, swelling, or palpable masses, particularly in long bones, pelvis, or chest wall, should discuss this testing with their oncologist. Early detection through genetic testing can significantly impact treatment outcomes and prognosis.
Benefits of EWSR1 Rearrangement Testing
Undergoing this specialized genetic analysis provides multiple clinical advantages:
- Accurate Diagnosis: Provides definitive genetic confirmation of Ewing sarcoma
- Treatment Guidance: Informs targeted therapy selection and treatment planning
- Prognostic Information: Helps assess disease aggressiveness and potential outcomes
- Differential Diagnosis: Distinguishes Ewing sarcoma from other similar malignancies
- Monitoring Capability: Enables tracking of treatment response and disease progression
Understanding Your Test Results
Your FISH Ewing Sarcoma test results will provide critical genetic information:
Positive Results
A positive result indicates the presence of EWSR1 gene rearrangement, confirming the diagnosis of Ewing sarcoma or related tumors. This finding supports the implementation of appropriate sarcoma-specific treatment protocols.
Negative Results
A negative result suggests the absence of characteristic EWSR1 rearrangements, potentially indicating a different type of cancer or tumor. Further diagnostic evaluation may be necessary to establish an accurate diagnosis.
Interpretation Guidance
All test results should be interpreted by qualified oncologists and genetic specialists in the context of clinical findings, imaging studies, and other diagnostic information. Our genetic counselors are available to help explain results and their implications.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $212 |
| Regular Price | $300 |
Sample Requirements and Processing
This test requires submission of formalin-fixed paraffin-embedded tissue blocks containing at least 10% tumor tissue. Samples should be shipped at room temperature, and completion of the Chromosome & FISH Analysis Requisition Form (Form 17) is mandatory for processing.
Nationwide Testing Availability
GGC DNA provides comprehensive FISH Ewing Sarcoma testing services across the United States, with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures accessible, high-quality genetic testing for patients throughout the country.
Take Action for Your Health
Early and accurate diagnosis is crucial for effective Ewing sarcoma management. Don’t delay in obtaining the genetic information needed for proper treatment planning. Our experienced team is ready to assist you with this important diagnostic testing.
Book Your Test Today: Call or WhatsApp us at +1(267) 388-9828 to schedule your FISH Ewing Sarcoma EWS 22q12 EWSR1 Rearrangement Test. Our genetic specialists are available to answer your questions and guide you through the testing process.
With results typically available within 7-8 working days, you can receive the critical genetic information needed for informed medical decisions and personalized treatment approaches. Trust GGC DNA for accurate, reliable genetic testing that makes a difference in cancer care.
