FISH Aneuploidy Detection Products of Conception POC Using Chromosomes 13, 18, 21, X, Y Test
Understanding FISH Aneuploidy Detection for Pregnancy Loss
The FISH Aneuploidy Detection Products of Conception test represents a breakthrough in reproductive genetic testing, offering couples experiencing pregnancy loss valuable insights into the chromosomal causes behind their miscarriage. This specialized diagnostic procedure utilizes advanced Fluorescence In Situ Hybridization technology to examine pregnancy tissue for chromosomal abnormalities that commonly lead to spontaneous abortions.
What Does This Test Measure?
This comprehensive genetic analysis specifically targets five critical chromosomes known to be frequently involved in pregnancy loss:
- Chromosome 13: Detects trisomy 13 (Patau syndrome)
- Chromosome 18: Identifies trisomy 18 (Edwards syndrome)
- Chromosome 21: Screens for trisomy 21 (Down syndrome)
- Chromosome X: Analyzes X chromosome abnormalities
- Chromosome Y: Detects Y chromosome variations
Who Should Consider This Test?
This specialized genetic testing is particularly recommended for:
- Couples experiencing recurrent pregnancy loss
- Women who have had multiple miscarriages
- Patients with unexplained infertility
- Couples seeking answers after spontaneous abortion
- Women over 35 experiencing pregnancy complications
- Patients with family history of chromosomal disorders
Clinical Indications and Symptoms
The test is especially valuable when pregnancy loss occurs without clear medical explanation. Common scenarios include:
- First-trimester miscarriages
- Recurrent pregnancy loss (two or more consecutive losses)
- Unexplained fetal demise
- Previous pregnancy with chromosomal abnormalities
- Advanced maternal age pregnancies
Benefits of FISH Aneuploidy Detection Testing
Choosing this advanced genetic analysis provides numerous advantages for couples navigating pregnancy loss:
- Closure and Understanding: Provides answers about the cause of pregnancy loss
- Future Planning: Helps guide decisions about future pregnancies
- Rapid Results: Delivers comprehensive analysis within just 4 days
- Accurate Diagnosis: Uses proven FISH technology for reliable results
- Genetic Counseling Support: Results can inform genetic counseling sessions
- Treatment Guidance: May influence future fertility treatment approaches
How the Test Works
The FISH technology employs fluorescent DNA probes that bind to specific chromosomal regions, allowing visualization of chromosome numbers and structures under a fluorescence microscope. This method provides rapid detection of numerical chromosomal abnormalities without the need for cell culture, making it ideal for analyzing products of conception tissue.
Understanding Your Test Results
Your FISH Aneuploidy Detection results will provide crucial information about the chromosomal status of the pregnancy tissue:
- Normal Results: Indicate no detected chromosomal abnormalities in the tested chromosomes
- Aneuploidy Detected: Identifies specific chromosomal abnormalities that likely caused the pregnancy loss
- Mosaic Results: May show mixed cell populations with different chromosomal patterns
- Inconclusive Results: Rare cases where tissue quality prevents definitive analysis
It’s important to discuss your results with your healthcare provider or genetic counselor to fully understand their implications for future family planning.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $212 |
| Regular Price | $300 |
Sample Requirements and Processing
For accurate testing, please provide:
- Placenta (villi) or appropriate tissue samples
- Fresh tissue from internal organs (if available)
- Chest wall cartilage (particularly if macerated) in normal saline
- Immediate shipping at 18-22°C
- Formalin fixed specimens are not acceptable
- Completed Chromosome & FISH analysis Requisition Form (Form 17)
Turnaround Time: Samples accepted daily by 4 pm, with results available within 4 days.
Nationwide Availability
We have diagnostic branches conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible genetic testing services nationwide.
Take the Next Step Toward Understanding
If you’re seeking answers about pregnancy loss, our FISH Aneuploidy Detection test provides the clarity and information you need. Our experienced genetic specialists and advanced laboratory facilities ensure accurate, reliable results to guide your reproductive health decisions.
Ready to schedule your test or have questions? Contact our genetic counseling team today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your reproductive health and planning for your future family.
Book Your Test Today
Don’t wait to get the answers you deserve. Our compassionate team is here to support you through every step of the testing process. Call us now at +1(267) 388-9828 to schedule your FISH Aneuploidy Detection test and take control of your reproductive health journey.
