FISH Aggressive Lymphoma Panel Test
Comprehensive Genetic Analysis for Lymphoma Diagnosis
The FISH Aggressive Lymphoma Panel Test represents a cutting-edge approach to lymphoma diagnosis and management. Utilizing Fluorescence In Situ Hybridization (FISH) technology, this specialized panel provides crucial genetic information that transforms how hematologists and oncologists approach lymphoma treatment. By detecting specific chromosomal abnormalities associated with aggressive lymphomas, this test enables precise disease classification and personalized treatment strategies.
What This Advanced Test Measures
The FISH Aggressive Lymphoma Panel specifically targets three critical genetic markers:
- BCL2 Rearrangements: Detects translocations involving the BCL2 gene, commonly associated with follicular lymphoma and some diffuse large B-cell lymphomas
- BCL6 Rearrangements: Identifies abnormalities in the BCL6 gene, often present in aggressive B-cell lymphomas
- c-MYC Rearrangements: Screens for c-MYC gene alterations, a hallmark of Burkitt lymphoma and high-grade B-cell lymphomas
Who Should Consider This Test
This comprehensive genetic panel is particularly valuable for patients experiencing:
- Unexplained lymph node enlargement that persists or grows rapidly
- Systemic symptoms including night sweats, unexplained fever, or significant weight loss
- Abnormal blood counts suggesting bone marrow involvement
- Previously diagnosed lymphoma requiring further genetic characterization
- Suspected transformation from indolent to aggressive lymphoma
- Poor response to initial lymphoma treatment
Clinical Benefits and Applications
The FISH Aggressive Lymphoma Panel offers multiple clinical advantages:
- Precise Diagnosis: Distinguishes between different lymphoma subtypes with similar appearances but different treatment requirements
- Treatment Guidance: Identifies patients who may benefit from targeted therapies or more intensive treatment regimens
- Prognostic Information: Provides insights into disease aggressiveness and likely clinical course
- Therapeutic Monitoring: Helps assess treatment response and detect early relapse
- Research Contribution: Contributes to ongoing understanding of lymphoma genetics and treatment development
Understanding Your Test Results
Your FISH Aggressive Lymphoma Panel results will provide detailed genetic information:
- Normal Results: No detectable rearrangements in BCL2, BCL6, or c-MYC genes
- Single Rearrangement: Indicates specific lymphoma subtypes with characteristic genetic profiles
- Double-Hit Lymphoma: Detection of rearrangements in two of the three genes, typically associated with more aggressive disease
- Triple-Hit Lymphoma: Presence of rearrangements in all three genes, indicating highly aggressive lymphoma requiring specialized treatment
Your hematologist or oncologist will interpret these results in the context of your complete clinical picture to develop the most appropriate treatment plan.
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $438 |
| Regular Price | $626 |
Nationwide Accessibility
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of collection centers ensures that advanced genetic testing is accessible to patients nationwide.
Take Control of Your Lymphoma Care
Don’t leave your lymphoma diagnosis to chance. The FISH Aggressive Lymphoma Panel provides the genetic clarity needed for optimal treatment decisions. With results available in just 4 working days and samples accepted daily until 4 PM, we make advanced genetic testing both accessible and timely.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Our team is available to answer your questions and guide you through the testing process, ensuring you receive the comprehensive care you deserve.

