F13A1 Gene Factor XIIIA Deficiency NGS Genetic DNA Test
Comprehensive Genetic Analysis for Bleeding Disorders
The F13A1 Gene Factor XIIIA Deficiency NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for bleeding disorders. This advanced test specifically targets the F13A1 gene, which encodes the A subunit of coagulation Factor XIII – a crucial enzyme in the final stage of blood clot formation. Factor XIII deficiency is a rare autosomal recessive bleeding disorder that affects approximately 1 in 2 million people worldwide, making accurate genetic diagnosis essential for proper management and treatment.
What Does This Test Measure?
Our NGS Genetic DNA Test employs cutting-edge Next-Generation Sequencing technology to comprehensively analyze the F13A1 gene for mutations associated with Factor XIII deficiency. The test detects:
- Point mutations in the F13A1 gene coding regions
- Small insertions and deletions affecting protein function
- Splice site mutations that disrupt normal gene expression
- Missense, nonsense, and frameshift mutations
- Regulatory region variants affecting gene expression
Who Should Consider This Test?
This genetic test is recommended for individuals experiencing:
- Unexplained bleeding episodes or excessive bruising
- Family history of bleeding disorders or Factor XIII deficiency
- Abnormal coagulation test results with normal routine clotting factors
- Delayed wound healing or abnormal scar formation
- Recurrent spontaneous abortions in females
- Intracranial hemorrhage without apparent cause
- Umbilical stump bleeding in newborns
Clinical Benefits of Genetic Testing
Undergoing the F13A1 Gene Factor XIIIA Deficiency NGS Genetic DNA Test provides numerous clinical advantages:
- Accurate Diagnosis: Confirms or rules out genetic Factor XIII deficiency with 99.9% accuracy
- Personalized Treatment: Enables targeted therapy with Factor XIII concentrate
- Genetic Counseling: Provides family planning guidance and inheritance risk assessment
- Early Intervention: Allows proactive management before serious bleeding complications occur
- Comprehensive Risk Assessment: Identifies carrier status for family members
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our board-certified genetic specialists:
- Positive Result: Indicates presence of pathogenic mutations in the F13A1 gene, confirming Factor XIII deficiency diagnosis
- Negative Result: Suggests no detectable mutations, though clinical correlation is essential
- Variant of Uncertain Significance: Requires additional family studies and clinical evaluation
- Carrier Status: Identifies individuals with one mutated copy who may pass the condition to offspring
Test Pricing Information
| Test Component | Price (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality testing results regardless of location.
Book Your Genetic Test Today
Take control of your health with comprehensive genetic testing. Our expert genetic counselors are available to discuss your testing options and provide personalized guidance. Contact us today to schedule your F13A1 Gene Factor XIIIA Deficiency NGS Genetic DNA Test and receive the answers you need for better health management.
Call or WhatsApp: +1(267) 388-9828 to book your appointment or speak with our genetic specialists.
Test Specifications
- Turnaround Time: 3 to 4 Weeks
- Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
- Technology: Next-Generation Sequencing (NGS)
- Specialty: Genetic Hematology
- Department: Genetics
- Pre-test Requirements: Clinical History and Genetic Counseling Session
