ERCC4 Gene XFE Progeroid Syndrome NGS Genetic DNA Test
Comprehensive Genetic Testing for Premature Aging Disorders
The ERCC4 Gene XFE Progeroid Syndrome NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare premature aging conditions. This advanced test specifically targets mutations in the ERCC4 gene, which plays a critical role in DNA repair mechanisms. When this gene malfunctions, it leads to XFE progeroid syndrome – a devastating condition characterized by accelerated aging symptoms that typically manifest in early childhood.
What Does This Test Measure?
Our NGS-based genetic test provides comprehensive analysis of the ERCC4 gene to identify pathogenic variants associated with XFE progeroid syndrome. The test specifically detects:
- Point mutations and small insertions/deletions in the ERCC4 gene
- Pathogenic variants affecting DNA nucleotide excision repair
- Genetic abnormalities that disrupt cellular aging processes
- Inherited mutations causing accelerated aging phenotypes
Who Should Consider This Test?
This genetic test is recommended for individuals displaying symptoms suggestive of premature aging disorders, including:
- Children showing signs of accelerated aging before puberty
- Individuals with growth retardation and developmental delays
- Patients with characteristic facial features of progeroid syndromes
- Those with family history of premature aging conditions
- Individuals with photosensitivity and skin abnormalities
- Patients with neurological abnormalities and cognitive impairment
Key Benefits of ERCC4 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Early Diagnosis: Enables timely intervention and management strategies
- Personalized Treatment: Guides targeted therapeutic approaches
- Family Planning: Provides crucial information for genetic counseling
- Disease Management: Helps anticipate and manage disease progression
- Research Contribution: Advances understanding of aging mechanisms
Understanding Your Test Results
Our genetic counselors provide comprehensive interpretation of your results:
- Positive Result: Indicates presence of pathogenic ERCC4 mutation requiring specialized care
- Negative Result: Suggests absence of tested mutations but may require additional testing
- Variant of Uncertain Significance: Requires ongoing monitoring and family studies
- Carrier Status: Important for family planning and genetic counseling
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | ERCC4 Gene XFE Progeroid Syndrome NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before undergoing testing, we recommend:
- Complete clinical history documentation
- Genetic counseling session with our specialists
- Development of family pedigree chart
- Discussion of potential outcomes and implications
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, and many other cities. Our network ensures accessible genetic testing services nationwide.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about premature aging symptoms affect your quality of life. Our expert genetic counselors are available to discuss your concerns and guide you through the testing process. Early detection through comprehensive genetic analysis can provide valuable insights for managing XFE progeroid syndrome and related conditions.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your ERCC4 Gene XFE Progeroid Syndrome NGS Genetic DNA Test. Our team is ready to provide the expert guidance and support you need for your genetic health journey.
