Eosinophilic Leukemia Panel FISH (PDGFRA, PDGFRB, FGFR1, C BFB)
Comprehensive Genetic Analysis for Eosinophilic Disorders
The Eosinophilic Leukemia Panel FISH test represents a cutting-edge diagnostic approach for identifying specific genetic abnormalities associated with eosinophilic leukemia and related hematologic conditions. This sophisticated molecular analysis utilizes Fluorescence In Situ Hybridization (FISH) technology to detect chromosomal rearrangements in key genes that regulate eosinophil development and function.
What This Advanced Test Measures
Our comprehensive panel specifically targets four critical genetic markers:
- PDGFRA (Platelet-Derived Growth Factor Receptor Alpha): Identifies rearrangements associated with chronic eosinophilic leukemia
- PDGFRB (Platelet-Derived Growth Factor Receptor Beta): Detects translocations linked to myeloid neoplasms with eosinophilia
- FGFR1 (Fibroblast Growth Factor Receptor 1): Screens for abnormalities in the 8p11 myeloproliferative syndrome
- C BFB (Chromosome Breakage Fusion Breakpoint): Assesses complex chromosomal rearrangements
Who Should Consider This Genetic Testing?
This specialized panel is recommended for individuals presenting with:
- Unexplained persistent eosinophilia (elevated eosinophil counts)
- Suspected hypereosinophilic syndrome
- Chronic eosinophilic leukemia symptoms
- Family history of eosinophilic disorders
- Poor response to conventional eosinophilia treatments
- Systemic symptoms including fatigue, fever, or organ involvement
Clinical Symptoms That May Indicate Testing Need
Patients experiencing any of the following symptoms should discuss testing with their healthcare provider:
- Persistent elevated eosinophil counts in blood tests
- Unexplained skin rashes or itching
- Respiratory symptoms including cough or wheezing
- Cardiac abnormalities or heart involvement
- Neurological symptoms such as numbness or tingling
- Gastrointestinal disturbances
- Constitutional symptoms like weight loss or night sweats
Significant Benefits of Genetic Testing
Undergoing the Eosinophilic Leukemia Panel FISH test provides multiple advantages:
- Accurate Diagnosis: Precise identification of specific genetic abnormalities
- Personalized Treatment: Guidance for targeted therapy selection
- Prognostic Information: Better understanding of disease progression
- Family Risk Assessment: Identification of potential hereditary factors
- Treatment Monitoring: Baseline for evaluating treatment response
- Reduced Diagnostic Uncertainty: Clear differentiation between similar conditions
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert team:
- Positive Result: Indicates the presence of specific genetic abnormalities, guiding targeted treatment approaches
- Negative Result: Suggests absence of tested mutations, helping rule out certain eosinophilic disorders
- Variant of Unknown Significance: Requires additional clinical correlation and possibly further testing
- Complex Rearrangements: May indicate more advanced disease requiring comprehensive management
All results include detailed interpretation and recommendations from our board-certified genetic specialists and hematologists.
Test Information and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | Eosinophilic Leukemia Panel FISH (PDGFRA, PDGFRB, FGFR1, C BFB) |
| Discount Price | $506 USD |
| Regular Price | $676 USD |
| Turnaround Time | 3-4 Days |
| Sample Type | Bone Marrow / Peripheral Blood (Transport Immediately) |
| Test Components | Sodium Heparin Vacutainer (2ml) |
| Prescription Requirement | Doctor’s Prescription Required (Not applicable for surgery, pregnancy, or international travel cases) |
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and Midwest locations
- Houston, Dallas, and Texas facilities
- Miami and Florida centers
- Washington DC and Baltimore areas
- San Francisco Bay Area locations
- And many more cities nationwide
Take Control of Your Health Today
Don’t let uncertainty about eosinophilic disorders delay your path to proper diagnosis and treatment. Our advanced genetic testing provides the clarity needed for effective medical management.
Ready to schedule your test? Contact our dedicated team today:
Phone: +1(267) 388-9828
Our genetic counseling team is available to answer your questions and help you understand the testing process. With rapid 3-4 day turnaround and comprehensive analysis, you’ll receive the critical information needed to guide your healthcare decisions.
Book your Eosinophilic Leukemia Panel FISH test now and take the first step toward precise diagnosis and targeted treatment.
