DPY19L2 Gene SPGF9 NGS Genetic DNA Test
Understanding DPY19L2 Gene Testing for Male Infertility
The DPY19L2 Gene SPGF9 NGS Genetic DNA Test represents a breakthrough in reproductive genetic diagnostics, specifically designed to identify mutations in the DPY19L2 gene that cause spermatogenic failure type 9 (SPGF9). This advanced genetic analysis plays a crucial role in diagnosing the underlying causes of male infertility, particularly in cases involving abnormal sperm morphology and function.
What Does the DPY19L2 Gene Test Measure?
This comprehensive genetic test utilizes Next-Generation Sequencing (NGS) technology to thoroughly analyze the DPY19L2 gene for mutations and variations. The test specifically detects:
- Point mutations and deletions in the DPY19L2 gene
- Genetic abnormalities responsible for globozoospermia
- Mutations causing acrosomal abnormalities in sperm
- Genetic variants associated with complete sperm head malformations
- Inherited patterns of spermatogenic failure
Who Should Consider DPY19L2 Genetic Testing?
This specialized genetic test is recommended for individuals and couples experiencing specific reproductive challenges:
Primary Candidates Include:
- Men diagnosed with globozoospermia (round-headed sperm)
- Couples experiencing unexplained male infertility
- Individuals with abnormal semen analysis showing acrosomal defects
- Patients with family history of male infertility
- Couples considering assisted reproductive technologies (ART)
- Individuals with previously failed IVF attempts
Common Symptoms and Indicators:
- Persistent infertility despite normal hormone levels
- Abnormal sperm morphology in semen analysis
- Round-headed sperm without proper acrosome formation
- Family history of reproductive difficulties
- Multiple failed fertility treatments
Benefits of DPY19L2 Genetic Testing
Undergoing DPY19L2 gene testing provides numerous advantages for couples facing fertility challenges:
Clinical Benefits:
- Accurate Diagnosis: Provides definitive identification of genetic causes for infertility
- Personalized Treatment Planning: Enables targeted fertility treatment strategies
- Genetic Counseling: Offers valuable information for family planning decisions
- Improved IVF Success: Helps optimize assisted reproduction techniques
- Risk Assessment: Evaluates inheritance patterns for future generations
Emotional and Practical Advantages:
- Reduces uncertainty about infertility causes
- Provides closure and understanding of reproductive challenges
- Enables informed decisions about fertility treatments
- Offers peace of mind through comprehensive genetic analysis
Understanding Your Test Results
Positive Result Interpretation:
A positive result indicates the presence of DPY19L2 gene mutations associated with SPGF9. This confirms the genetic basis for globozoospermia and provides crucial information for:
- Treatment strategy development
- Genetic counseling sessions
- Family planning decisions
- Potential use of advanced reproductive technologies
Negative Result Interpretation:
A negative result suggests that DPY19L2 gene mutations are not the cause of the fertility issues, guiding healthcare providers to investigate other potential causes of infertility.
Variant of Uncertain Significance (VUS):
In some cases, the test may identify genetic variations with unknown clinical significance. Our genetic counselors provide comprehensive guidance on interpreting these results and determining next steps.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $500 |
| Regular Price | $700 |
Test Details:
- Turnaround Time: 3 to 4 Weeks
- Sample Type: Blood, Extracted DNA, or One Drop Blood on FTA Card
- Methodology: Next-Generation Sequencing (NGS) Technology
- Specialty: Reproductive Genetics
Pre-Test Requirements
Before undergoing DPY19L2 genetic testing, patients should provide:
- Complete clinical history related to fertility challenges
- Previous semen analysis reports
- Family medical history documentation
- Participation in genetic counseling session to create family pedigree chart
Nationwide Availability Across USA
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic testing facilities ensures accessible, reliable testing nationwide.
Take the Next Step Toward Understanding Your Fertility
Don’t let unexplained infertility create uncertainty in your life. The DPY19L2 Gene SPGF9 NGS Genetic DNA Test provides the answers you need to make informed decisions about your reproductive health and family planning journey.
Call us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our compassionate genetic specialists are ready to guide you through the testing process and help you understand your results.
Take control of your reproductive health with advanced genetic testing from General Genetics Corporation – your partner in comprehensive genetic diagnostics.
