DLX5 Gene Split-Hand/Foot Malformation Type 1 with Sensorineural Hearing Loss NGS Genetic DNA Test
Comprehensive Genetic Analysis for Congenital Limb and Hearing Disorders
The DLX5 Gene Split-Hand/Foot Malformation Type 1 with Sensorineural Hearing Loss NGS Genetic DNA Test represents a cutting-edge diagnostic approach for identifying genetic mutations associated with this rare congenital condition. Using advanced Next-Generation Sequencing (NGS) technology, our test provides unparalleled accuracy in detecting variations within the DLX5 gene that are responsible for both limb malformations and hearing impairment.
What This Test Measures and Detects
This comprehensive genetic test specifically targets the DLX5 gene, which plays a crucial role in embryonic development of limbs and auditory systems. The test identifies:
- Pathogenic mutations in the DLX5 gene associated with split-hand/foot malformation
- Genetic variations causing sensorineural hearing loss
- Inheritance patterns and carrier status
- Specific mutation types including missense, nonsense, and frameshift variants
- De novo mutations in sporadic cases
Who Should Consider This Test
This genetic test is recommended for individuals presenting with:
- Congenital split-hand or split-foot malformations
- Unexplained sensorineural hearing loss from birth or early childhood
- Family history of limb abnormalities combined with hearing impairment
- Children with developmental delays involving both limbs and hearing
- Individuals with suspected genetic syndromes involving multiple systems
- Couples with family history planning pregnancy
Clinical Symptoms and Indications
Patients may exhibit various clinical features including:
- Missing fingers or toes with cleft formation in hands or feet
- Progressive or congenital hearing loss
- Asymmetrical limb involvement
- Associated skeletal abnormalities
- Developmental delays in severe cases
Benefits of Taking the DLX5 Genetic Test
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Confirms the genetic basis of symptoms, eliminating diagnostic uncertainty
- Family Planning Guidance: Provides recurrence risk information for future pregnancies
- Early Intervention: Enables timely management strategies for hearing and limb function
- Personalized Treatment: Guides appropriate therapeutic approaches based on genetic findings
- Genetic Counseling: Supports informed decision-making for affected families
- Research Contribution: Helps advance understanding of rare genetic disorders
Understanding Your Test Results
Our comprehensive genetic counseling service helps interpret your results:
- Positive Result: Confirms DLX5 gene mutation; enables targeted management and family screening
- Negative Result: Suggests other genetic or environmental causes; guides further investigation
- Variant of Uncertain Significance: Requires additional family studies and clinical correlation
- Carrier Status: Important for reproductive planning and genetic counseling
Test Details and Pricing
| Test Feature | Details |
|---|---|
| Test Name | DLX5 Gene Split-Hand/Foot Malformation Type 1 with Sensorineural Hearing Loss NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before testing, we require:
- Complete clinical history of the patient
- Genetic counseling session to create a detailed family pedigree
- Documentation of affected family members
- Informed consent for genetic testing
Nationwide Availability Across USA
We have convenient testing locations throughout the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities. Our network of certified genetic counselors and medical professionals ensures accessible, high-quality care regardless of your location.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about genetic conditions affect your family’s future. Our DLX5 genetic test provides the answers you need for informed medical decisions and family planning. With our discounted price of $500 USD and comprehensive genetic counseling support, you can gain valuable insights into this complex condition.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your DLX5 genetic test. Our team of genetic specialists is ready to guide you through every step of the testing process and help you understand your results.
