Cytochrome P450 2C19 Genotyping CYP2C19 Clopidogrel Resistance Test
Understanding Your Genetic Response to Clopidogrel Medication
The Cytochrome P450 2C19 Genotyping CYP2C19 Clopidogrel Resistance Test represents a breakthrough in personalized cardiovascular medicine. This advanced genetic analysis examines how your body processes clopidogrel, a widely prescribed antiplatelet medication used to prevent blood clots in patients with heart conditions, stroke history, or peripheral artery disease. Understanding your genetic profile can significantly impact treatment effectiveness and cardiovascular outcomes.
What This Test Measures and Detects
Our comprehensive genetic analysis focuses on the CYP2C19 gene, specifically targeting four critical genetic variations:
- CYP2C19*2 variant: The most common loss-of-function allele affecting clopidogrel metabolism
- CYP2C19*3 variant: Another significant loss-of-function mutation
- CYP2C19*4 variant: Additional genetic variation impacting drug activation
- CYP2C19*10 variant: Genetic marker influencing medication response
These genetic variations determine whether you are an extensive metabolizer, intermediate metabolizer, poor metabolizer, or ultra-rapid metabolizer of clopidogrel. Each metabolic profile carries different implications for treatment effectiveness and cardiovascular risk management.
Who Should Consider This Genetic Test
This test is particularly important for individuals in the following situations:
- Patients prescribed clopidogrel for cardiovascular conditions
- Individuals with a history of stent thrombosis or recurrent cardiovascular events
- Patients undergoing coronary artery stenting procedures
- Those with family history of poor response to antiplatelet medications
- Individuals experiencing breakthrough cardiovascular events while on clopidogrel therapy
- Patients considering long-term antiplatelet therapy
- Those with unexplained treatment resistance to standard medication regimens
Significant Benefits of Genetic Testing
Undergoing CYP2C19 genotyping provides numerous advantages for your cardiovascular health:
- Personalized Treatment Planning: Tailor medication choices based on your genetic profile
- Reduced Cardiovascular Risk: Optimize antiplatelet therapy to prevent future events
- Improved Medication Safety: Avoid ineffective treatments and potential complications
- Enhanced Treatment Efficacy: Ensure you receive the most appropriate antiplatelet therapy
- Informed Medical Decisions: Empower yourself and your healthcare provider with genetic insights
- Cost-Effective Healthcare: Prevent unnecessary medication trials and complications
Understanding Your Test Results
Your genetic test results will categorize you into one of four metabolic phenotypes:
- Extensive Metabolizer: Normal clopidogrel metabolism – standard dosing typically effective
- Intermediate Metabolizer: Reduced metabolic activity – may require alternative dosing or monitoring
- Poor Metabolizer: Significantly impaired metabolism – high risk of treatment failure, alternative medications recommended
- Ultra-Rapid Metabolizer: Enhanced metabolic activity – may require different therapeutic approaches
It’s crucial to discuss your results with your healthcare provider to determine the most appropriate treatment strategy based on your genetic profile and clinical situation.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $150 |
| Regular Price | $200 |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Take Control of Your Cardiovascular Health
Don’t leave your medication response to chance. Understanding your genetic profile can make a significant difference in your cardiovascular treatment outcomes. Our advanced Sanger sequencing technology provides accurate, reliable results within 7 days, giving you and your healthcare provider the information needed to make informed treatment decisions.
Ready to optimize your cardiovascular treatment? Book your Cytochrome P450 2C19 Genotyping test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Take the first step toward personalized, effective cardiovascular care.
Note: This test requires a doctor’s prescription for most cases. Prescription requirements do not apply for surgical preparation, pregnancy-related testing, or international travel documentation purposes.
