CSF Leakage Evaluation Nasal/Ear Discharge Test
Understanding Cerebrospinal Fluid Leak Diagnosis
Cerebrospinal fluid (CSF) leakage represents a serious medical condition where the protective fluid surrounding the brain and spinal cord escapes through tears or defects in the surrounding membranes. Our CSF Leakage Evaluation Nasal/Ear Discharge Test provides definitive diagnosis through advanced laboratory analysis, helping healthcare providers identify and treat this potentially dangerous condition before complications develop.
What This Test Measures and Detects
This specialized diagnostic test employs nephelometry technology to measure Beta-2 Transferrin Protein (BTP) concentrations in both nasal/ear discharge samples and patient serum. The test evaluates three critical components:
- BTP in CSF/Discharge: Detects the presence of cerebrospinal fluid in nasal or ear discharge
- BTP in Serum: Establishes baseline protein levels in blood serum
- BTP Ratio: Calculates the relationship between discharge and serum levels to confirm CSF leakage
Who Should Consider CSF Leakage Testing
This test is essential for individuals experiencing specific symptoms following head trauma, surgical procedures, or spontaneous occurrences. Consider testing if you experience:
- Clear, watery nasal drainage that worsens when bending forward
- Persistent ear drainage following head injury or surgery
- Salty or metallic taste in the mouth from nasal discharge
- Recurrent meningitis or severe headaches
- Recent skull base surgery or traumatic head injury
- Spontaneous clear fluid drainage without infection symptoms
Clinical Importance and Benefits
Early detection of CSF leaks provides numerous clinical advantages:
- Prevention of Serious Complications: Identifies leaks before meningitis or brain infections develop
- Accurate Diagnosis: Provides definitive evidence of CSF leakage when clinical suspicion exists
- Treatment Guidance: Helps ENT surgeons and neurosurgeons plan appropriate interventions
- Rapid Results: Same-day reporting enables timely medical decision-making
- Non-Invasive Sampling: Simple collection process with minimal patient discomfort
Understanding Your Test Results
Your CSF Leakage Evaluation results will provide clear guidance for next steps:
- Positive Result: Indicates confirmed CSF leakage, requiring consultation with ENT or neurosurgical specialists for repair planning
- Negative Result: Rules out active CSF leakage, though clinical correlation with symptoms remains important
- Borderline Findings: May require repeat testing or additional imaging studies for confirmation
All results should be discussed with your healthcare provider who will interpret them in the context of your specific symptoms and medical history.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $188 |
| Regular Price | $238 |
Convenient Testing Across the United States
GGC DNA maintains testing facilities in all major US cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures accessible CSF leakage evaluation services with consistent quality standards and rapid turnaround times.
Sample Collection and Processing
For optimal results, please note these important collection guidelines:
- Sample Requirements: 2 mL (1 mL minimum) nasal/ear discharge in sterile container AND 2 mL (1 mL minimum) serum in SST tube
- Shipping Instructions: Refrigerate samples during transport – DO NOT FREEZE
- Submission Schedule: Samples accepted Monday and Thursday by 9:00 AM
- Reporting: Same-day results available for properly submitted specimens
- Preparation: No special patient preparation required before testing
Take Action for Your Neurological Health
Don’t ignore potential CSF leakage symptoms. Early diagnosis and treatment can prevent serious complications and ensure optimal recovery outcomes. Our specialized testing provides the definitive answers you and your healthcare team need to make informed treatment decisions.
Ready to schedule your CSF Leakage Evaluation? Contact our dedicated patient services team today at +1(267) 388-9828 to book your appointment or discuss your testing needs with our medical professionals. We’re here to help you get the answers you need for proper diagnosis and treatment.

