Copper 24-Hour Urine Test: Comprehensive Wilson’s Disease Screening
Understanding the Copper 24-Hour Urine Test
The Copper 24-Hour Urine Test is a sophisticated diagnostic assessment that provides critical insights into copper metabolism within the human body. This specialized test measures the total amount of copper excreted in urine over a complete 24-hour period, offering healthcare providers valuable information about copper processing and elimination. Copper is an essential trace mineral required for numerous physiological functions, including energy production, iron metabolism, and nervous system maintenance. However, when copper accumulates to toxic levels, it can cause severe damage to vital organs, particularly the liver and brain.
What This Test Measures and Detects
The Copper 24-Hour Urine Test specifically quantifies:
- Total copper excretion over 24 hours
- Copper metabolism efficiency
- Potential copper accumulation disorders
- Wilson’s disease diagnostic markers
- Liver copper processing capacity
Using advanced Inductively Coupled Plasma Mass Spectrometry (ICP-MS) technology, our laboratory provides highly accurate measurements of copper levels. This methodology ensures precise detection of even subtle abnormalities in copper metabolism, enabling early intervention and appropriate treatment planning.
Who Should Consider This Test?
Symptoms and Clinical Indications
This test is particularly important for individuals experiencing:
- Unexplained liver enzyme abnormalities or liver dysfunction
- Neurological symptoms including tremors, difficulty with speech, or coordination problems
- Psychiatric manifestations such as depression, anxiety, or personality changes
- Family history of Wilson’s disease or other metabolic disorders
- Kayser-Fleischer rings (copper deposits in the eyes)
- Unexplained fatigue, jaundice, or abdominal pain
- Suspected copper metabolism disorders
Gastroenterologists and ophthalmologists frequently recommend this test for patients showing signs of copper-related disorders. The test is especially crucial for individuals between 5-35 years old, as Wilson’s disease typically manifests during these years.
Benefits of Taking the Copper 24-Hour Urine Test
- Early Disease Detection: Identifies Wilson’s disease before irreversible organ damage occurs
- Accurate Diagnosis: Provides definitive diagnostic information for copper metabolism disorders
- Treatment Guidance: Helps healthcare providers develop appropriate treatment strategies
- Family Screening: Essential for screening family members of diagnosed Wilson’s disease patients
- Monitoring Tool: Useful for monitoring treatment effectiveness in diagnosed patients
- Comprehensive Assessment: Offers insights into overall copper metabolism and liver function
Understanding Your Test Results
Normal Range Interpretation
Normal copper excretion in a 24-hour urine collection typically ranges between 10-50 micrograms per 24 hours. Results within this range generally indicate normal copper metabolism and elimination.
Abnormal Results Guidance
- Elevated Levels: Significantly increased copper excretion (usually >100 mcg/24 hours) strongly suggests Wilson’s disease, particularly when accompanied by low blood ceruloplasmin levels
- Borderline Results: Moderately elevated levels may require additional testing and clinical correlation
- Low Levels: While less common, decreased copper excretion might indicate copper deficiency or other metabolic issues
It’s essential to discuss your results with a qualified healthcare provider who can interpret them in the context of your overall clinical picture, symptoms, and other laboratory findings.
Test Information and Pricing
| Test Component | Price (USD) |
|---|---|
| Copper 24-Hour Urine Test | $60 |
| Discount Price | $54 |
Turnaround Time and Sample Requirements
Turnaround: Samples accepted daily by 6 PM with next-day reporting
Sample Type: 10 mL (5 mL minimum) aliquot of 24-hour urine collected in an acid-washed (metal-free) container
Special Instructions: If barium-containing contrast media has been administered, wait 96 hours before specimen collection
Convenient Testing Locations Across the USA
GGC DNA has branches conveniently located throughout the United States, making the Copper 24-Hour Urine Test easily accessible to patients nationwide. Our state-of-the-art facilities in major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose ensure that you receive the highest quality diagnostic services close to home.
Take Control of Your Health Today
Don’t wait to address potential copper metabolism issues. Early detection of Wilson’s disease and other copper-related disorders can prevent serious complications and preserve your quality of life. Our experienced team is ready to assist you with comprehensive testing and accurate results.
Book your Copper 24-Hour Urine Test today by calling +1(267) 388-9828 or via WhatsApp. Take the first step toward understanding your copper metabolism and protecting your long-term health.

