CLL Panel Deletion/Duplication Detection
Comprehensive Genetic Testing for Chronic Lymphocytic Leukemia
The CLL Panel Deletion/Duplication Detection represents a cutting-edge genetic screening approach specifically designed for patients with Chronic Lymphocytic Leukemia. This advanced diagnostic tool utilizes MLPA (Multiplex Ligation-dependent Probe Amplification) technology to identify critical chromosomal abnormalities that significantly impact disease progression, treatment response, and overall prognosis in CLL patients.
What This Test Measures and Detects
Our specialized CLL genetic panel focuses on identifying specific deletion and duplication events in chromosomes and genes known to influence CLL behavior:
- TP53 Gene Abnormalities: Detects deletions in the TP53 tumor suppressor gene, which are associated with treatment resistance and poor prognosis
- ATM Gene Deletions: Identifies abnormalities in the ATM gene that affect DNA repair mechanisms
- NOTCH1 Mutations: Screens for genetic alterations linked to disease transformation
- Chromosome 13q14 Deletions: Detects the most common chromosomal abnormality in CLL
- Chromosome 11q22-23 Deletions: Identifies high-risk genetic markers
- Trisomy 12 Detection: Screens for additional chromosome 12 copies
Who Should Consider CLL Genetic Testing
This comprehensive genetic panel is recommended for individuals experiencing:
- Unexplained fatigue, weakness, or night sweats
- Enlarged lymph nodes without apparent infection
- Abnormal complete blood count results showing elevated lymphocytes
- Family history of hematologic cancers or CLL
- Recent CLL diagnosis requiring prognostic stratification
- Patients considering targeted therapy options
- Individuals with recurrent infections or autoimmune symptoms
Clinical Benefits of CLL Genetic Testing
Undergoing CLL Panel Deletion/Duplication Detection provides numerous clinical advantages:
- Personalized Treatment Planning: Genetic results guide selection of appropriate targeted therapies
- Prognostic Stratification: Identifies high-risk versus low-risk disease categories
- Early Intervention Opportunities: Enables proactive management of aggressive disease variants
- Treatment Response Prediction: Helps anticipate how patients may respond to specific medications
- Disease Monitoring: Provides baseline genetic profile for tracking disease evolution
- Family Risk Assessment: Offers insights into potential hereditary components
Understanding Your Test Results
Your CLL genetic test results will provide detailed information about specific chromosomal abnormalities:
- Normal Results: No significant deletions or duplications detected in tested regions
- Low-Risk Profile: Isolated 13q14 deletions typically indicate favorable prognosis
- Intermediate Risk: Trisomy 12 findings suggest moderate disease aggressiveness
- High-Risk Markers: TP53 or ATM deletions indicate need for aggressive treatment approaches
- Complex Findings: Multiple abnormalities may suggest advanced disease stage
All results should be discussed with your hematologist or oncologist for proper interpretation and treatment planning.
Test Pricing and Availability
| Test Component | Details |
|---|---|
| Test Name | CLL Panel Deletion/Duplication Detection |
| Discount Price | $262 USD |
| Regular Price | $350 USD |
| Turnaround Time | 7-10 days |
| Sample Type | Bone marrow / Peripheral blood (Transport immediately) |
| Test Components | EDTA Vacutainer (2ml) |
| Testing Method | MLPA (Multiplex Ligation-dependent Probe Amplification) |
Nationwide Testing Availability
We have conveniently located testing centers across the United States, including major metropolitan areas:
- New York City and surrounding tri-state area
- Los Angeles and Southern California region
- Chicago and Illinois metropolitan area
- Houston and Texas Gulf Coast
- Phoenix and Arizona valley locations
- Philadelphia and Delaware Valley centers
- All other major US cities and regional hubs
Important Pre-Test Instructions
The CLL Panel Deletion/Duplication Detection requires a physician’s prescription for testing. Please note that prescription requirements do not apply to surgical cases, pregnancy-related testing, or individuals planning international travel. Our genetic counselors are available to discuss testing indications and help coordinate sample collection.
Take Control of Your Health Today
Don’t wait to get the critical genetic information needed for optimal CLL management. Our specialized oncology genetics team is ready to assist you with comprehensive testing and personalized result interpretation.
Call or WhatsApp us now at +1(267) 388-9828 to schedule your CLL genetic testing appointment. Our genetic specialists will guide you through the testing process and ensure you receive the most accurate and clinically relevant results for your condition.
Early genetic characterization of Chronic Lymphocytic Leukemia can significantly impact treatment success and long-term outcomes. Trust our experienced oncology genetics laboratory to provide the precise diagnostic information your healthcare team needs for informed decision-making.
