CLL FISH Panel: Comprehensive Chromosomal Analysis for Chronic Lymphocytic Leukemia
Understanding the CLL FISH Panel Test
The CLL FISH Panel represents a cutting-edge diagnostic approach in hematologic oncology, specifically designed to detect chromosomal abnormalities in Chronic Lymphocytic Leukemia (CLL). This sophisticated genetic test utilizes Fluorescence In Situ Hybridization (FISH) technology to identify specific chromosomal alterations that significantly impact disease prognosis and treatment strategies. By analyzing four critical genetic markers, this panel provides oncologists with essential information to guide personalized treatment approaches and predict disease behavior.
What Does the CLL FISH Panel Measure?
This comprehensive genetic panel specifically targets four key chromosomal abnormalities that are clinically significant in CLL:
- Deletion 11q (del11q): Associated with more aggressive disease and poorer prognosis
- Trisomy 12: Indicates intermediate prognosis with variable clinical outcomes
- Deletion 13q (del13q): Considered the most favorable prognostic marker
- Deletion 17p (del17p): Indicates high-risk disease with treatment resistance
Who Should Consider This Test?
The CLL FISH Panel is recommended for individuals who:
- Have been newly diagnosed with Chronic Lymphocytic Leukemia
- Are experiencing unexplained lymphocytosis or enlarged lymph nodes
- Show abnormal blood counts suggestive of lymphoid malignancies
- Require prognostic stratification for treatment planning
- Need monitoring of disease progression or treatment response
- Have family history of hematologic malignancies
Clinical Indications and Symptoms
Patients presenting with symptoms such as persistent fatigue, unexplained weight loss, night sweats, recurrent infections, or palpable lymph nodes should discuss genetic testing with their healthcare provider. Early detection of chromosomal abnormalities can significantly influence treatment decisions and long-term outcomes.
Benefits of CLL FISH Panel Testing
- Precise Prognostic Information: Identifies genetic risk factors that predict disease course
- Personalized Treatment Planning: Guides selection of targeted therapies based on genetic profile
- Early Intervention Opportunities: Enables proactive management of high-risk genetic features
- Improved Survival Outcomes: Helps optimize treatment strategies for better long-term results
- Comprehensive Risk Assessment: Provides multi-faceted genetic evaluation in a single test
Understanding Your Test Results
Your CLL FISH Panel results will provide detailed information about the presence or absence of specific chromosomal abnormalities:
Result Interpretation Guide
- Normal Results: No detected chromosomal abnormalities – generally favorable prognosis
- del13q Only: Most favorable prognostic group with excellent treatment response
- Trisomy 12: Intermediate prognosis requiring careful monitoring
- del11q: Higher risk disease requiring aggressive treatment approaches
- del17p: Highest risk category necessitating specialized targeted therapies
It’s crucial to discuss your specific results with your oncologist, as treatment decisions should consider multiple clinical factors beyond genetic markers alone.
Test Pricing and Details
| Test Component | Details |
|---|---|
| Test Name | CLL FISH Panel: del(11q), Trisomy 12, del(13q), del(17p) |
| Discount Price | $376 USD |
| Regular Price | $496 USD |
| Turnaround Time | 10 Days |
| Sample Type | Bone Marrow / Peripheral Blood (Transport Immediately) |
| Test Components | Sodium Heparin Vacutainer (2ml) |
Pre-Test Instructions
The CLL FISH Panel requires a doctor’s prescription for testing. Please note that prescriptions are not applicable for surgery and pregnancy cases or individuals planning to travel abroad. Ensure proper sample collection and immediate transportation to maintain sample integrity.
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Take Control of Your Health Today
Don’t leave your leukemia diagnosis to chance. The CLL FISH Panel provides critical genetic information that can significantly impact your treatment journey and long-term outcomes. Our experienced genetic counselors and oncology specialists are ready to help you understand your results and navigate next steps.
Ready to schedule your CLL FISH Panel test? Contact our dedicated patient care team at +1(267) 388-9828 to book your appointment or discuss testing options with our genetic specialists. Early genetic testing can make a profound difference in your leukemia management strategy.
