Chromofic Karyoarray Test: Advanced Chromosomal Microarray Analysis
Comprehensive Introduction to Chromosomal Microarray Testing
The Chromofic Karyoarray Test represents a revolutionary advancement in genetic diagnostics, offering unprecedented resolution for detecting chromosomal abnormalities. This sophisticated testing methodology combines high-density microarray technology with traditional cytogenetic approaches to provide comprehensive genetic insights that were previously undetectable through conventional methods.
As a premier diagnostic tool in the field of cytogenetics, the Chromofic Karyoarray Test has become the gold standard for evaluating patients with neurological disorders, developmental delays, and unexplained clinical presentations. The test’s ability to identify submicroscopic chromosomal changes makes it particularly valuable for uncovering the genetic basis of complex neurological conditions that often remain undiagnosed through standard genetic testing.
What the Chromofic Karyoarray Test Detects
This advanced genetic screening test specifically identifies:
- Microdeletions and microduplications (copy number variations)
- Chromosomal imbalances and rearrangements
- Submicroscopic chromosomal abnormalities
- Regions of homozygosity indicating potential consanguinity
- Chromosomal mosaicism at lower levels than detectable by traditional karyotyping
- Uniparental disomy in specific genomic regions
Technical Methodology
The Chromofic Karyoarray Test utilizes the Affymetrix CytoScan 750K microarray platform, which provides exceptional genomic coverage with over 750,000 markers across the entire human genome. This high-resolution approach is complemented by microscopic analysis to ensure comprehensive chromosomal evaluation.
Who Should Consider Chromofic Karyoarray Testing
This test is particularly recommended for individuals presenting with:
- Unexplained developmental delays or intellectual disability
- Autism spectrum disorders or related behavioral conditions
- Multiple congenital anomalies without clear diagnosis
- Neurological symptoms of unknown origin
- Family history of chromosomal abnormalities
- Previous normal karyotype results with persistent clinical concerns
- Prenatal findings suggestive of chromosomal abnormalities
- Unexplained seizures or movement disorders
Significant Benefits of Chromosomal Microarray Analysis
Choosing the Chromofic Karyoarray Test provides numerous advantages:
- Higher Diagnostic Yield: Detects 15-20% more abnormalities than traditional karyotyping
- Comprehensive Coverage: Screens the entire genome simultaneously
- Enhanced Resolution: Identifies changes as small as 50-100 kilobases
- Clinical Guidance: Provides actionable information for treatment planning
- Family Planning Insights: Offers recurrence risk information for future pregnancies
- Early Intervention: Enables timely therapeutic interventions
Understanding Your Test Results
Your Chromofic Karyoarray Test results will be carefully interpreted by our board-certified genetic specialists and cytogeneticists. Results typically fall into three categories:
Pathogenic Findings
These results indicate clinically significant chromosomal abnormalities that explain the patient’s symptoms. Our genetic counselors will provide detailed explanations and discuss management options, recurrence risks, and available resources.
Variants of Uncertain Significance (VUS)
Some findings may represent genetic variations whose clinical significance is currently unknown. Our team will guide you through the implications and may recommend additional family studies or follow-up testing.
Normal Results
A normal result indicates no detectable chromosomal abnormalities within the resolution of the test. This information can help narrow the diagnostic focus and guide further medical evaluation.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Chromofic Karyoarray Test | $800 USD | $1000 USD |
Turnaround Time and Sample Requirements
Turnaround: Samples accepted daily by 4 PM; Reports delivered within 10 working days
Sample Type: 4 mL (2 mL minimum) whole blood in 1 Lavender Top (EDTA) tube AND 4 mL (2 mL minimum) whole blood in 1 Green Top (Sodium Heparin) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomic Microarray Requisition form (Form 19) is mandatory.
Nationwide Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, with branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures convenient access to advanced genetic testing services regardless of your location.
Take the Next Step Toward Genetic Clarity
If you or your loved one is experiencing unexplained neurological symptoms or developmental concerns, the Chromofic Karyoarray Test could provide the answers you need. Our team of genetic specialists is ready to guide you through the testing process and help interpret your results within the context of your specific clinical situation.
Ready to schedule your Chromofic Karyoarray Test? Contact our genetic counseling team today at +1(267) 388-9828 or book your appointment online. Take advantage of our current discounted pricing of $800 USD and gain valuable insights into your genetic health.
