CFHR1 Gene Hemolytic Uremic Syndrome NGS Genetic DNA Test
Comprehensive Genetic Analysis for Kidney and Blood Disorders
The CFHR1 Gene Hemolytic Uremic Syndrome NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for individuals at risk of developing atypical hemolytic uremic syndrome (aHUS). This sophisticated test employs next-generation sequencing technology to identify mutations in the CFHR1 gene, which plays a critical role in regulating the complement system—a vital component of our immune defense mechanism.
What Does This Test Measure?
This advanced genetic test specifically targets and analyzes the CFHR1 gene to detect:
- Point mutations and single nucleotide variations in the CFHR1 gene
- Gene deletions and duplications affecting complement regulation
- Genetic variants associated with complement dysregulation
- Mutations that predispose individuals to atypical HUS development
- Inherited genetic patterns that may affect family members
Who Should Consider This Test?
This genetic test is particularly recommended for individuals experiencing:
- Unexplained kidney failure or acute renal impairment
- Hemolytic anemia with fragmented red blood cells (schistocytes)
- Thrombocytopenia (low platelet count) without clear cause
- Family history of hemolytic uremic syndrome or kidney disorders
- Recurrent episodes of microangiopathic hemolytic anemia
- Patients with complement-mediated kidney diseases
- Individuals with atypical HUS symptoms not responding to standard treatments
Key Benefits of CFHR1 Genetic Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Confirms or rules out genetic predisposition to atypical HUS
- Personalized Treatment: Guides targeted therapy with complement inhibitors
- Family Planning: Identifies inheritance patterns for genetic counseling
- Early Intervention: Enables proactive monitoring of at-risk individuals
- Disease Management: Helps predict disease course and potential complications
- Therapeutic Guidance: Informs decisions about eculizumab and other specific treatments
Understanding Your Test Results
Your genetic test results will be carefully interpreted by our expert genetic counselors and medical specialists:
- Positive Result: Indicates the presence of CFHR1 gene mutation associated with increased aHUS risk
- Negative Result: Suggests no detected mutation in the CFHR1 gene analyzed
- Variant of Uncertain Significance: Identifies genetic changes with unknown clinical impact requiring further evaluation
- Carrier Status: Determines if you carry a single copy of a mutation that could be passed to offspring
All positive results include comprehensive genetic counseling to help you understand the implications for your health and family members.
Test Pricing and Details
| Test Feature | Details |
|---|---|
| Test Name | CFHR1 Gene Hemolytic Uremic Syndrome NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood, Extracted DNA, or One Drop Blood on FTA Card |
| Testing Method | Next-Generation Sequencing (NGS) Technology |
Pre-Test Requirements
Before scheduling your test, please ensure:
- Complete clinical history documentation of the patient
- Genetic counseling session to create a detailed family pedigree chart
- Identification of family members affected by CFHR1-related disorders
- Discussion of test implications with a genetic specialist
Nationwide Availability
We proudly serve patients across the United States with convenient testing locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic testing facilities ensures accessible, reliable service nationwide.
Take Control of Your Genetic Health Today
Don’t let uncertainty about your genetic risk for hemolytic uremic syndrome compromise your health. Our comprehensive CFHR1 genetic test provides the clarity you need to make informed decisions about your healthcare journey. With advanced NGS technology and expert interpretation, you’ll receive accurate, actionable genetic information.
Ready to schedule your test? Contact our genetic specialists today at +1(267) 388-9828 or book your appointment online. Take the first step toward understanding your genetic predisposition and protecting your kidney health.
