CDC73 Gene Hyperparathyroidism Type 2 Familial NGS Genetic DNA Test
Comprehensive Genetic Testing for Familial Hyperparathyroidism
The CDC73 Gene Hyperparathyroidism Type 2 Familial NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for hereditary endocrine disorders. This advanced next-generation sequencing (NGS) test specifically targets the CDC73 gene, which plays a critical role in regulating parathyroid function and calcium metabolism. Familial hyperparathyroidism-jaw tumor syndrome is a rare autosomal dominant condition that significantly increases the risk of parathyroid tumors, jaw fibromas, and various kidney pathologies.
What This Test Measures and Detects
Our comprehensive genetic analysis utilizes cutting-edge NGS technology to identify specific mutations in the CDC73 gene, including:
- Point mutations and small insertions/deletions affecting CDC73 gene function
- Genetic variants associated with hyperparathyroidism-jaw tumor syndrome
- Hereditary predisposition to parathyroid adenomas and carcinomas
- Genetic markers for increased risk of kidney cysts and Wilms tumors
- Familial inheritance patterns of endocrine disorders
Who Should Consider This Genetic Test
This test is particularly recommended for individuals experiencing:
- Unexplained hypercalcemia or elevated parathyroid hormone levels
- Family history of parathyroid tumors or endocrine disorders
- Recurrent kidney stones or renal complications
- Jaw tumors or fibromas of the mandible or maxilla
- Early-onset hyperparathyroidism (before age 40)
- Multiple endocrine neoplasia-like symptoms without confirmed diagnosis
- Planning pregnancy with family history of CDC73-related disorders
Clinical Benefits of Genetic Testing
Undergoing the CDC73 genetic test provides numerous advantages for proactive healthcare management:
- Early Intervention: Identify genetic risk before symptoms develop
- Personalized Monitoring: Create targeted surveillance plans for at-risk individuals
- Family Planning: Make informed reproductive decisions with genetic counseling
- Treatment Guidance: Inform surgical and medical management strategies
- Risk Assessment: Determine inheritance patterns for family members
- Peace of Mind: Reduce uncertainty through definitive genetic information
Understanding Your Test Results
Our comprehensive genetic report provides clear, actionable information:
- Positive Result: Indicates presence of CDC73 mutation, confirming diagnosis of hyperparathyroidism-jaw tumor syndrome. Requires regular monitoring and specialist consultation.
- Negative Result: No CDC73 mutation detected, significantly reducing hereditary risk. However, continued clinical monitoring may be recommended based on family history.
- Variant of Uncertain Significance: Rare genetic changes with unknown clinical impact. Requires periodic re-evaluation as research advances.
Test Pricing and Availability
| Test Description | Price |
|---|---|
| CDC73 Gene Hyperparathyroidism Type 2 Familial NGS Genetic DNA Test – Discount Price | $500 USD |
| CDC73 Gene Hyperparathyroidism Type 2 Familial NGS Genetic DNA Test – Regular Price | $700 USD |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified genetic counselors and healthcare professionals ensures accessible, high-quality care regardless of your location.
Pre-Test Requirements and Sample Collection
Before testing, we recommend:
- Comprehensive clinical history documentation
- Genetic counseling session to create detailed family pedigree
- Discussion of testing implications and potential outcomes
Sample Options: Blood draw, extracted DNA, or single blood drop on FTA card
Turnaround Time: 3-4 weeks from sample receipt
Testing Methodology: Next-Generation Sequencing (NGS) Technology
Take Control of Your Genetic Health Today
Don’t let uncertainty about hereditary conditions affect your health decisions. The CDC73 Gene Hyperparathyroidism Type 2 Familial NGS Genetic DNA Test provides the clarity you need for informed healthcare planning. Our team of genetic specialists, endocrinologists, and nephrologists are ready to support you through every step of the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Take the first step toward understanding your genetic health and protecting your future well-being.
