CBFB-MYH11 Inv(16) Qualitative Test
Understanding the CBFB-MYH11 Inv(16) Qualitative Test
The CBFB-MYH11 Inv(16) Qualitative test represents a cutting-edge molecular diagnostic approach for detecting specific genetic abnormalities associated with acute myeloid leukemia (AML). This sophisticated test utilizes Real Time PCR technology to identify the chromosomal inversion between chromosomes 16p13 and 16q22, which creates a fusion gene between the CBFB and MYH11 genes. This genetic alteration is particularly significant as it defines a distinct subtype of AML with unique clinical characteristics and treatment responses.
What This Test Measures and Detects
The CBFB-MYH11 Inv(16) Qualitative test specifically targets and identifies:
- The presence of the inv(16)(p13q22) chromosomal inversion
- The CBFB-MYH11 fusion gene transcript
- Genetic markers associated with core-binding factor acute myeloid leukemia
- Molecular evidence for AML-M4Eo subtype classification
Who Should Consider This Test
This genetic test is recommended for individuals experiencing:
- Unexplained fatigue, weakness, or persistent tiredness
- Frequent infections or unusual susceptibility to illness
- Unexplained bruising, bleeding, or petechiae
- Bone pain or tenderness
- Enlarged lymph nodes, spleen, or liver
- Abnormal blood cell counts on routine testing
- Previous diagnosis of AML requiring subtype confirmation
- Monitoring treatment response in known CBFB-MYH11 positive AML
Clinical Benefits of Testing
Undergoing the CBFB-MYH11 Inv(16) Qualitative test provides numerous advantages:
- Accurate Diagnosis: Precise identification of AML subtype for targeted treatment planning
- Prognostic Information: Understanding disease course and expected outcomes
- Treatment Guidance: Informing chemotherapy and targeted therapy decisions
- Minimal Residual Disease Monitoring: Tracking treatment effectiveness over time
- Early Detection: Identifying genetic abnormalities before full disease manifestation
- Family Planning Insights: Understanding genetic implications for future generations
Understanding Your Test Results
Your CBFB-MYH11 Inv(16) Qualitative test results will be clearly interpreted by our genetic specialists:
- Positive Result: Indicates the presence of the CBFB-MYH11 fusion gene, confirming inv(16) associated AML
- Negative Result: Suggests absence of this specific genetic abnormality, though other AML subtypes may still be present
- Quantitative Values: When applicable, provides information about mutation burden for monitoring purposes
All results are accompanied by comprehensive explanations and recommendations for next steps. Our genetic counselors are available to discuss your results and answer any questions you may have about their implications for your health and treatment options.
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | CBFB-MYH11 Inv(16) Qualitative |
| Regular Price | $150 USD |
| Discount Price | $112 USD |
| Turnaround Time | 3-4 Days |
| Sample Type | Bone Marrow / Peripheral Blood (Transport Immediately) |
| Test Components | EDTA Vacutainer (2ml) |
| Testing Method | Real Time PCR |
| Specialty | General Physician |
Pre-Test Instructions and Requirements
The CBFB-MYH11 Inv(16) Qualitative test requires a Doctor’s prescription for most cases. However, prescription requirements do not apply for:
- Surgical preparation cases
- Pregnancy-related testing
- Individuals planning international travel requiring medical documentation
For all other circumstances, please consult with your healthcare provider to obtain the necessary prescription before scheduling your test.
Nationwide Availability
GGC DNA has testing facilities conveniently located across the United States, serving patients in all major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and the Midwest
- Houston, Dallas, and Texas locations
- Miami and Florida centers
- Washington D.C. and Baltimore areas
- San Francisco and Bay Area facilities
- And many more locations nationwide
Take Control of Your Health Today
Don’t wait to get the critical genetic information you need for proper diagnosis and treatment planning. The CBFB-MYH11 Inv(16) Qualitative test provides essential insights into your genetic health and can significantly impact your treatment journey.
Ready to schedule your test? Contact us today:
Phone: +1(267) 388-9828
WhatsApp: +1(267) 388-9828
Our friendly staff is available to answer your questions, help you understand the testing process, and schedule your appointment at the most convenient location. Take the first step toward comprehensive genetic understanding and personalized medical care.
