Cardiolipin Antibody IgG Test
Understanding the Cardiolipin Antibody IgG Test
The Cardiolipin Antibody IgG Test represents a critical diagnostic tool in modern autoimmune medicine, specifically designed to detect immunoglobulin G (IgG) antibodies that target cardiolipin molecules. Cardiolipin is an essential phospholipid component found predominantly in mitochondrial membranes and plays a vital role in cellular energy production. When the immune system mistakenly produces antibodies against cardiolipin, it can trigger a cascade of autoimmune responses that significantly impact blood coagulation pathways.
This specialized test holds particular importance in the diagnosis and management of antiphospholipid syndrome (APS), a complex autoimmune disorder characterized by abnormal blood clotting tendencies. The detection of IgG class antibodies provides valuable clinical information, as IgG antibodies are known to persist longer in the bloodstream and are more strongly associated with thrombotic complications compared to other antibody classes.
What the Test Measures and Detects
The Cardiolipin Antibody IgG Test specifically measures the concentration of IgG immunoglobulins that bind to cardiolipin antigens. Using state-of-the-art Enzyme Immunoassay methodology, our laboratory provides precise quantitative results that help clinicians:
- Detect autoimmune responses against phospholipid components
- Identify patients at risk for thrombotic events
- Monitor disease activity in established antiphospholipid syndrome
- Assess the risk of pregnancy-related complications
- Evaluate unexplained coagulation abnormalities
The test measures antibody levels in standardized units, allowing for accurate tracking of changes over time and providing critical data for treatment decisions.
Who Should Consider This Test
Clinical Indications and Symptoms
Several patient populations benefit from Cardiolipin Antibody IgG testing, particularly individuals presenting with:
- Unexplained Thrombosis: Patients with deep vein thrombosis, pulmonary embolism, or arterial clots without clear risk factors
- Recurrent Pregnancy Loss: Women experiencing multiple miscarriages, especially during the second or third trimester
- Autoimmune Symptoms: Individuals with features suggestive of systemic lupus erythematosus or other autoimmune conditions
- Unexplained Thrombocytopenia: Patients with low platelet counts without obvious cause
- Neurological Symptoms: Those experiencing strokes, transient ischemic attacks, or cognitive changes at a young age
- Pregnancy Complications: Women with severe preeclampsia, placental insufficiency, or intrauterine growth restriction
Benefits of Taking the Cardiolipin Antibody IgG Test
Undergoing Cardiolipin Antibody IgG testing offers numerous advantages for both patients and healthcare providers:
- Early Risk Identification: Detect potential thrombotic risks before serious complications occur
- Pregnancy Management: Enable appropriate interventions to support successful pregnancies in at-risk women
- Treatment Guidance: Inform decisions regarding anticoagulant therapy and immunosuppressive treatments
- Comprehensive Evaluation: Provide essential data for complete thrombophilia workups
- Peace of Mind: Offer clarity for patients with unexplained symptoms or family history of clotting disorders
- Same-Day Results: Receive timely information with our efficient testing process
Understanding Your Test Results
Interpretation Guidelines
Your Cardiolipin Antibody IgG test results will fall into one of several categories, each with specific clinical implications:
- Negative/Normal Range: Indicates no detectable IgG antibodies against cardiolipin, suggesting low probability of antiphospholipid syndrome
- Low Positive: May require repeat testing and correlation with clinical symptoms
- Moderate to High Positive: Strongly suggestive of antiphospholipid syndrome, especially when accompanied by clinical criteria
- Persistently Positive: Confirms diagnosis when positive results are documented on two or more occasions at least 12 weeks apart
It’s important to note that test interpretation should always be performed by qualified healthcare professionals who can consider your complete clinical picture, including symptoms, medical history, and additional laboratory findings.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Cardiolipin Antibody IgG Test – Discount Price | $24 |
| Cardiolipin Antibody IgG Test – Regular Price | $26 |
Testing Details
- Turnaround Time: Same-day results when samples collected Monday through Saturday by 9 AM
- Sample Requirements: 2 mL (1 mL minimum) serum from 1 SST tube
- Shipping Instructions: Ship refrigerated or frozen
- Preparation: No special preparation required
- Testing Method: Enzyme Immunoassay
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified laboratories ensures consistent, high-quality results regardless of your location.
Take Action for Your Health
Don’t let uncertainty about potential autoimmune or clotting disorders compromise your health and wellbeing. The Cardiolipin Antibody IgG Test provides crucial information that can guide effective treatment strategies and prevent serious complications. Our experienced team is ready to assist you with convenient testing options and professional support throughout the process.
Book your Cardiolipin Antibody IgG Test today by calling +1(267) 388-9828 or visiting your nearest GGC DNA testing center. Take the first step toward comprehensive autoimmune evaluation and personalized care.

