AZF Region Gene Azoospermia Y Chromosome Microdeletions NGS Genetic DNA Test
Comprehensive Genetic Testing for Male Infertility
The AZF Region Gene Azoospermia Y Chromosome Microdeletions NGS Genetic DNA Test represents a breakthrough in male reproductive health diagnostics. This advanced genetic screening utilizes Next Generation Sequencing (NGS) technology to identify specific microdeletions on the Y chromosome that are directly responsible for impaired sperm production and male infertility. Understanding the genetic basis of infertility is crucial for developing effective treatment strategies and making informed reproductive decisions.
What Does This Test Detect?
This sophisticated genetic analysis specifically targets and identifies microdeletions in three critical AZF (Azoospermia Factor) regions on the Y chromosome:
- AZFa Region Deletions: Complete deletion typically results in Sertoli-cell-only syndrome with complete absence of sperm production
- AZFb Region Deletions: Causes maturation arrest during spermatogenesis, preventing sperm development
- AZFc Region Deletions: Most common deletion type, associated with variable sperm production from severe oligospermia to azoospermia
- Combined AZF Deletions: Multiple region deletions that significantly impact fertility potential
Who Should Consider This Test?
This genetic screening is recommended for men experiencing specific reproductive health challenges:
- Men diagnosed with azoospermia (complete absence of sperm in semen)
- Individuals with severe oligospermia (extremely low sperm count)
- Couples undergoing fertility evaluation with unexplained male factor infertility
- Men with family history of male infertility or reproductive disorders
- Patients considering assisted reproductive technologies like IVF or ICSI
- Individuals with abnormal semen analysis results requiring genetic investigation
Clinical Benefits of AZF Microdeletion Testing
Understanding your genetic profile provides numerous advantages for fertility management:
- Accurate Diagnosis: Pinpoints the specific genetic cause of infertility
- Treatment Guidance: Helps determine the most appropriate fertility treatments
- Genetic Counseling: Provides essential information for family planning decisions
- Prognostic Value: Predicts potential success rates for sperm retrieval procedures
- Informed Decisions: Enables couples to make educated choices about reproductive options
- Early Intervention: Facilitates timely medical management and treatment planning
Understanding Your Test Results
Your genetic test results will provide clear insights into your reproductive health:
- Normal Result: No AZF region microdeletions detected, suggesting other causes for infertility
- AZFa Deletion: Indicates severe spermatogenic failure with poor prognosis for sperm retrieval
- AZFb Deletion: Suggests maturation arrest with limited treatment options
- AZFc Deletion: Variable outcomes with potential for sperm retrieval in some cases
- Partial Deletions: May have different implications for fertility potential
All results are accompanied by comprehensive genetic counseling to help you understand the implications and next steps.
Test Pricing Information
| Test Name | Discount Price | Regular Price |
|---|---|---|
| AZF Region Gene Azoospermia Y Chromosome Microdeletions NGS Genetic DNA Test | $500 USD | $700 USD |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our state-of-the-art genetic testing facilities ensure consistent, reliable results regardless of your location.
Take Control of Your Reproductive Health Today
Don’t let unanswered questions about your fertility hold you back. Our AZF Region Gene Azoospermia Y Chromosome Microdeletions NGS Genetic DNA Test provides the clarity you need to move forward with confidence. With results available in 3-4 weeks and requiring only a simple blood sample or extracted DNA, this comprehensive genetic analysis is your first step toward understanding and addressing male infertility.
Ready to begin your journey to answers? Book your test today by calling our dedicated genetic counseling team at +1(267) 388-9828 or schedule your appointment online. Take the first step toward understanding your reproductive health and exploring your treatment options.
