Anti-DNase B Test: Comprehensive Streptococcal Infection Detection
Understanding the Anti-DNase B Test
The Anti-DNase B test is a crucial diagnostic tool that measures antibodies against deoxyribonuclease B, an enzyme produced by Group A Streptococcus bacteria. This sophisticated laboratory analysis plays a vital role in detecting recent or past streptococcal infections, particularly when patients present with complications that may not show obvious symptoms of the initial infection.
Streptococcal infections can lead to serious autoimmune complications, including rheumatic fever and post-streptococcal glomerulonephritis. The Anti-DNase B test provides essential information about the body’s immune response to these bacterial infections, helping healthcare providers make accurate diagnoses and develop appropriate treatment plans.
What Does the Anti-DNase B Test Measure?
This specialized test detects and quantifies immunoglobulin G (IgG) antibodies that specifically target the DNase B enzyme produced by Group A Streptococcus bacteria. When the immune system encounters this bacterial enzyme, it produces antibodies as part of the defense mechanism. The test measures:
- Presence of anti-DNase B antibodies in the bloodstream
- Antibody concentration levels to determine recent infection
- Immune system response to streptococcal exposure
- Evidence of past or current streptococcal infections
Who Should Consider This Test?
The Anti-DNase B test is recommended for individuals experiencing symptoms or conditions that may indicate streptococcal infection complications:
Symptoms and Clinical Indications
- Unexplained fever following a sore throat
- Joint pain and swelling without apparent cause
- Cardiac symptoms suggesting rheumatic fever
- Kidney problems or changes in urine output
- Skin rashes following respiratory infections
- Suspected post-streptococcal complications
- Monitoring treatment response in confirmed cases
High-Risk Groups
- Children and young adults with recurrent sore throats
- Patients with family history of rheumatic fever
- Individuals living in crowded conditions
- Patients with compromised immune systems
Benefits of Taking the Anti-DNase B Test
Choosing the Anti-DNase B test provides numerous advantages for accurate diagnosis and proper management:
- Early Detection: Identifies streptococcal infections even when throat cultures are negative
- Complication Prevention: Helps prevent serious autoimmune complications
- Treatment Guidance: Informs appropriate antibiotic therapy decisions
- Comprehensive Assessment: Often used alongside ASO titer testing for complete evaluation
- Long-term Monitoring: Tracks antibody levels over time to monitor disease progression
- Peace of Mind: Provides clarity for unexplained symptoms
Understanding Your Test Results
Interpreting Anti-DNase B test results requires professional medical expertise, but here’s general guidance:
Normal Results
- Adults: Less than 85 units/mL
- School-age children: Less than 170 units/mL
- Preschool children: Less than 60 units/mL
Elevated Levels May Indicate
- Recent streptococcal infection
- Rheumatic fever
- Post-streptococcal glomerulonephritis
- Scarlet fever
- Other streptococcal-related conditions
Important Considerations
- Antibody levels typically peak 4-6 weeks after infection
- Results should be interpreted alongside clinical symptoms
- Serial testing may be needed to track antibody trends
- Consult with your healthcare provider for personalized interpretation
Test Information and Pricing
| Test Details | Information |
|---|---|
| Test Name | Anti-DNase B Test |
| Regular Price | $40 USD |
| Discount Price | $36 USD |
| Sample Type | 2 mL (1 mL min.) serum from 1 SST |
| Turnaround Time | Sample Tue/Fri by 9 am; Report Same Day |
| Testing Method | Latex Enhanced Nephelometry |
| Preparation | No special preparation required |
Nationwide Testing Availability
We have branches across all major cities in the United States, ensuring convenient access to the Anti-DNase B test. Our network includes locations in:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and the Midwest region
- Houston and Texas locations
- Phoenix and Arizona facilities
- Philadelphia and East Coast centers
- And many more locations nationwide
Book Your Anti-DNase B Test Today
Don’t let unexplained symptoms go undiagnosed. The Anti-DNase B test provides crucial information for detecting streptococcal infections and preventing serious complications. Our state-of-the-art laboratory facilities and expert medical team ensure accurate, reliable results you can trust.
Take control of your health today! Call or WhatsApp us at +1(267) 388-9828 to schedule your Anti-DNase B test. Our friendly staff will assist you with appointment scheduling, answer any questions, and help you understand the testing process.
With same-day reporting available and no special preparation required, getting tested has never been easier or more convenient. Trust our experienced rheumatologists, ENT specialists, and physicians to provide the comprehensive care you deserve.

