AIP Gene Pituitary Adenoma Growth Hormone-Secreting NGS Genetic DNA Test
Comprehensive Genetic Testing for Hereditary Pituitary Disorders
The AIP Gene Pituitary Adenoma Growth Hormone-Secreting NGS Genetic DNA Test represents a breakthrough in genetic medicine, offering precise detection of germline mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) gene. This specialized test is designed to identify individuals at risk for developing hereditary pituitary adenomas, particularly those that secrete growth hormone, leading to conditions like acromegaly and gigantism.
What Does This Test Measure?
This advanced genetic screening utilizes Next-Generation Sequencing (NGS) technology to comprehensively analyze the entire AIP gene for pathogenic variants. The test specifically detects:
- Germline mutations in the AIP gene associated with familial isolated pituitary adenoma (FIPA)
- Genetic variants that predispose individuals to growth hormone-secreting pituitary tumors
- Inherited mutations that increase risk for early-onset acromegaly
- Specific nucleotide changes, insertions, deletions, and copy number variations in the AIP gene
Who Should Consider This Test?
This genetic test is particularly recommended for individuals experiencing:
- Family history of pituitary tumors or acromegaly
- Unexplained growth abnormalities in children or adolescents
- Early-onset acromegaly symptoms (before age 30)
- Multiple family members with pituitary disorders
- Personal history of pituitary adenoma with suspicious genetic patterns
- Unexplained gigantism or accelerated growth patterns
Clinical Symptoms and Indications
Patients with AIP gene mutations may present with various symptoms including:
- Progressive enlargement of hands, feet, and facial features
- Excessive sweating and oily skin
- Joint pain and arthritis
- Deepened voice and enlarged tongue
- Vision changes or headaches
- Menstrual irregularities in women
- Erectile dysfunction in men
- Cardiovascular complications
Benefits of AIP Genetic Testing
Early Detection and Prevention
Identifying AIP gene mutations enables proactive medical management through:
- Regular pituitary imaging and hormone level monitoring
- Early intervention before significant tumor growth occurs
- Prevention of long-term complications associated with acromegaly
- Improved treatment outcomes through timely diagnosis
Family Planning and Genetic Counseling
The test results provide valuable information for:
- Informed reproductive decisions
- Genetic counseling for at-risk family members
- Understanding inheritance patterns (autosomal dominant with reduced penetrance)
- Developing personalized surveillance strategies for family members
Personalized Treatment Approaches
Positive test results guide healthcare providers in creating:
- Tailored treatment plans based on genetic profile
- Appropriate surgical or medical management strategies
- Long-term follow-up protocols
- Multidisciplinary care coordination
Understanding Your Test Results
Positive Result Interpretation
A positive result indicates the presence of a pathogenic AIP gene mutation:
- Confirms genetic predisposition to pituitary adenomas
- Requires regular endocrine monitoring and pituitary imaging
- Suggests genetic testing for first-degree relatives
- May influence treatment decisions and surgical planning
Negative Result Interpretation
A negative result provides important clinical information:
- No detected pathogenic AIP gene mutations
- Reduced likelihood of hereditary pituitary adenoma syndrome
- May still require clinical monitoring based on symptoms
- Does not completely rule out other genetic causes
Variant of Uncertain Significance (VUS)
Some results may identify genetic variants with unclear clinical implications:
- Requires correlation with clinical findings
- May need additional family studies
- Periodic re-evaluation as genetic knowledge advances
- Close clinical follow-up recommended
Test Details and Pricing
| Test Component | Details |
|---|---|
| Test Name | AIP Gene Pituitary Adenoma Growth Hormone-Secreting NGS Genetic DNA Test |
| Discount Price | $500 USD |
| Regular Price | $700 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood |
| Testing Method | Next-Generation Sequencing (NGS) |
| Specialty | Oncologist, Genetics |
Pre-Test Requirements
Before undergoing testing, patients should complete:
- Comprehensive clinical history documentation
- Genetic counseling session with certified genetic counselor
- Development of detailed family pedigree chart
- Discussion of potential results and implications
- Informed consent process
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified genetic testing facilities ensures accessible, reliable testing services nationwide.
Take Control of Your Genetic Health Today
Don’t wait to understand your genetic risk for hereditary pituitary disorders. Early detection through AIP gene testing can significantly impact your long-term health outcomes and provide peace of mind for you and your family.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your AIP Gene Pituitary Adenoma Growth Hormone-Secreting NGS Genetic DNA Test. Our genetic specialists are available to answer your questions and guide you through the testing process.
Take the first step toward proactive health management and informed medical decision-making. Book your test now and gain valuable insights into your genetic predisposition for pituitary disorders.
