AGT Gene Renal Tubular Dysgenesis NGS Genetic DNA Test
Comprehensive Genetic Analysis for Kidney Development Disorders
The AGT Gene Renal Tubular Dysgenesis NGS Genetic DNA Test represents a breakthrough in genetic diagnostics for rare kidney disorders. This advanced test specifically targets mutations in the angiotensinogen (AGT) gene, which plays a critical role in the renin-angiotensin system – the body’s primary mechanism for regulating blood pressure and fluid balance. Renal tubular dysgenesis is a severe congenital condition characterized by underdevelopment of kidney tubules, leading to life-threatening complications in newborns and infants.
What This Test Measures and Detects
Our NGS-based genetic test provides comprehensive analysis of the AGT gene to identify:
- Pathogenic variants and mutations in the angiotensinogen gene
- Single nucleotide polymorphisms (SNPs) affecting gene function
- Deletions, insertions, and copy number variations
- Genetic markers associated with impaired kidney development
- Inheritance patterns of renal tubular dysgenesis
Who Should Consider This Test
This genetic test is recommended for individuals experiencing:
- Family history of renal tubular dysgenesis or unexplained kidney failure in infants
- Newborns with oligohydramnios sequence (Potter sequence)
- Infants presenting with pulmonary hypoplasia and renal abnormalities
- Unexplained fetal or neonatal deaths with kidney involvement
- Individuals with suspected angiotensinogen deficiency disorders
- Couples with previous affected pregnancies planning future family
Key Symptoms and Clinical Indicators
- Persistent fetal anuria or oliguria
- Severe hypotension unresponsive to treatment
- Characteristic facial features (Potter facies)
- Respiratory distress due to pulmonary hypoplasia
- Abnormal kidney development on prenatal ultrasound
- Family history of similar renal conditions
Benefits of AGT Gene Testing
Undergoing this comprehensive genetic analysis provides numerous advantages:
- Accurate Diagnosis: Precise identification of AGT gene mutations enables definitive diagnosis
- Family Planning Guidance: Understand inheritance risks for future pregnancies
- Personalized Treatment: Tailored medical management based on genetic findings
- Early Intervention: Potential for prenatal diagnosis and early medical care
- Genetic Counseling: Informed decision-making for affected families
- Research Contribution: Advance understanding of rare kidney disorders
Understanding Your Test Results
Our comprehensive genetic report provides clear interpretation of your results:
Positive Result Interpretation
A positive result indicates the presence of pathogenic mutations in the AGT gene associated with renal tubular dysgenesis. This confirms the genetic basis of the condition and provides crucial information for medical management and family planning.
Negative Result Interpretation
A negative result suggests that no disease-causing mutations were detected in the AGT gene. However, this does not completely rule out the possibility of renal tubular dysgenesis, as other genetic or environmental factors may be involved.
Variant of Uncertain Significance (VUS)
Some genetic changes may be classified as VUS, meaning their clinical significance is currently unknown. Our genetic counselors will provide guidance on monitoring and further testing recommendations.
Test Information and Pricing
| Test Feature | Details |
|---|---|
| Test Name | AGT Gene Renal Tubular Dysgenesis NGS Genetic DNA Test |
| Regular Price | $700 USD |
| Discount Price | $500 USD |
| Turnaround Time | 3 to 4 Weeks |
| Sample Type | Blood |
| Testing Method | Next-Generation Sequencing (NGS) |
Pre-Test Requirements
Before scheduling your test, please ensure you have:
- Complete clinical history of the patient
- Genetic counseling session scheduled
- Pedigree chart of family members affected with AGT gene disorders
- Relevant medical records and previous test results
Nationwide Availability
We have conveniently located branches across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities nationwide. Our state-of-the-art facilities ensure consistent, high-quality testing regardless of location.
Take the Next Step Toward Genetic Clarity
Don’t let uncertainty about genetic kidney disorders affect your family’s future. Our AGT Gene Renal Tubular Dysgenesis NGS Genetic DNA Test provides the answers you need for informed medical decisions and family planning.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your genetic counseling session and book your test. Our compassionate genetic specialists are ready to guide you through every step of the testing process and help you understand your results.
Take control of your genetic health with comprehensive, accurate testing from America’s leading genetics corporation. Book your appointment now and receive the clarity you deserve for only $500 USD.
