ACTA2 Gene Moyamoya Disease Type 5 NGS Genetic DNA Test
Comprehensive Genetic Testing for Cardiovascular Health
The ACTA2 Gene Moyamoya Disease Type 5 NGS Genetic DNA Test represents a breakthrough in cardiovascular genetic medicine, offering precise detection of mutations associated with Moyamoya disease type 5. This specialized test provides critical insights for individuals and families affected by this rare cerebrovascular condition, enabling proactive healthcare management and informed decision-making.
What is ACTA2 Gene Moyamoya Disease?
Moyamoya disease type 5 is a rare, progressive cerebrovascular disorder characterized by the narrowing of arteries at the base of the brain, primarily affecting the internal carotid arteries. The condition creates a characteristic “puff of smoke” appearance on angiography (moyamoya means “puff of smoke” in Japanese). The ACTA2 gene encodes smooth muscle alpha-actin, a crucial protein in vascular smooth muscle cells, and mutations in this gene can lead to abnormal blood vessel development and increased stroke risk.
What Does This Test Measure?
Our advanced NGS Genetic DNA Test specifically analyzes:
- Complete sequencing of the ACTA2 gene for pathogenic variants
- Detection of specific mutations associated with Moyamoya disease type 5
- Identification of inherited genetic patterns
- Assessment of cardiovascular and neurological risk factors
- Comprehensive variant analysis with clinical correlation
Who Should Consider This Test?
Clinical Indications and Symptoms
This genetic test is recommended for individuals experiencing:
- Unexplained transient ischemic attacks (TIAs) or strokes at young age
- Family history of Moyamoya disease or early-onset cerebrovascular events
- Progressive neurological symptoms including headaches, seizures, or cognitive decline
- Abnormal brain imaging showing characteristic Moyamoya patterns
- Multiple family members with cardiovascular or cerebrovascular conditions
- Children with developmental delays and suspected vascular abnormalities
Benefits of ACTA2 Genetic Testing
Early Detection and Prevention
Undergoing the ACTA2 Gene Moyamoya Disease Type 5 NGS Genetic DNA Test provides numerous advantages:
- Early Intervention: Identify genetic risk before symptom onset
- Personalized Treatment: Tailor medical management based on genetic profile
- Family Planning: Make informed reproductive decisions
- Proactive Monitoring: Implement appropriate surveillance protocols
- Surgical Planning: Guide revascularization procedures when needed
- Psychological Relief: Reduce uncertainty through definitive diagnosis
Understanding Your Test Results
Comprehensive Genetic Counseling
Our genetic specialists provide detailed interpretation of your results:
- Positive Result: Indicates presence of ACTA2 mutation associated with Moyamoya disease type 5. Our team will discuss management strategies, surveillance recommendations, and family testing options.
- Negative Result: No pathogenic ACTA2 variants detected. However, clinical follow-up may still be recommended based on symptoms and family history.
- Variant of Uncertain Significance: Some genetic changes require additional research. We provide ongoing monitoring and reclassification as new evidence emerges.
Test Information and Pricing
| Test Component | Details | Price (USD) |
|---|---|---|
| Test Name | ACTA2 Gene Moyamoya Disease Type 5 NGS Genetic DNA Test | – |
| Discount Price | Limited Time Offer | $500 |
| Regular Price | Standard Rate | $700 |
| Turnaround Time | Comprehensive Analysis | 3-4 Weeks |
| Sample Type | Blood Sample | Included |
| Genetic Counseling | Pre and Post-Test Sessions | Included |
Nationwide Accessibility
We have conveniently located branches across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Take Control of Your Cardiovascular Health
Don’t let genetic uncertainty compromise your health future. The ACTA2 Gene Moyamoya Disease Type 5 NGS Genetic DNA Test provides the clarity needed for effective cardiovascular management and family planning. Our team of certified genetic counselors and cardiovascular specialists are ready to guide you through every step of the testing process.
Ready to schedule your genetic test? Contact our dedicated team today:
Phone: +1(267) 388-9828
Our genetic specialists are available to answer your questions and help you book your appointment at a location convenient for you.
