INV(16)(p13q22) Gene Rearrangement Qualitative PCR Test
Understanding the INV(16)(p13q22) Genetic Test
The INV(16)(p13q22) Gene Rearrangement Qualitative PCR Test represents a cutting-edge molecular diagnostic approach for detecting specific chromosomal abnormalities in acute myeloid leukemia (AML). This sophisticated test identifies the inversion of chromosome 16, a critical genetic event that leads to the formation of the CBFB-MYH11 fusion gene. This fusion gene plays a pivotal role in the development and progression of a specific subtype of AML, making its detection essential for accurate diagnosis and targeted treatment strategies.
What Does This Test Measure?
This advanced PCR-based test specifically detects:
- The inversion of chromosome 16 at bands p13 and q22
- Formation of the CBFB-MYH11 fusion gene
- Presence of specific genetic markers associated with AML-M4Eo subtype
- Qualitative assessment of gene rearrangement status
Who Should Consider This Test?
This genetic test is particularly important for individuals presenting with:
- Unexplained fatigue and weakness
- Frequent infections or fever without apparent cause
- Easy bruising or abnormal bleeding
- Pale skin or shortness of breath
- Bone pain or tenderness
- Abnormal blood cell counts on routine testing
- Suspected or newly diagnosed acute myeloid leukemia
Clinical Indications
Hematologists and oncologists typically recommend this test for:
- Initial diagnosis and classification of AML
- Risk stratification and prognosis assessment
- Treatment planning and therapeutic decision-making
- Monitoring treatment response and minimal residual disease
- Differentiating AML subtypes for targeted therapy
Benefits of Taking the INV(16)(p13q22) Test
Undergoing this genetic analysis provides numerous advantages:
- Accurate Diagnosis: Precise identification of specific AML subtypes
- Personalized Treatment: Enables targeted therapy approaches
- Prognostic Information: Helps predict disease course and outcomes
- Treatment Monitoring: Allows assessment of treatment effectiveness
- Early Detection: Facilitates timely intervention and management
- Comprehensive Care: Supports integrated hematology-oncology management
Understanding Your Test Results
Your test results will be interpreted by our expert molecular pathologists:
Positive Result
A positive result indicates the presence of the INV(16)(p13q22) rearrangement, confirming the diagnosis of AML with this specific genetic abnormality. This finding typically correlates with a favorable prognosis and may guide specific treatment recommendations.
Negative Result
A negative result suggests the absence of this specific genetic rearrangement. However, this does not rule out other forms of AML or hematological disorders, and further testing may be recommended based on clinical presentation.
Clinical Correlation
All results should be interpreted in the context of your complete clinical picture, including symptoms, physical examination findings, and other laboratory test results. Your hematologist or oncologist will provide comprehensive guidance based on these integrated findings.
Test Pricing Information
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $150 |
| Regular Price | $200 |
Test Specifications
- Turnaround Time: Samples accepted Monday/Thursday by 11 AM; Reports delivered Wednesday/Saturday
- Sample Type: 3 mL (2 mL minimum) whole blood or Bone Marrow from 1 Lavender Top (EDTA) tube
- Shipping Instructions: Ship refrigerated. DO NOT FREEZE
- Required Documentation: Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory
- Testing Method: Real-Time PCR Technology
Nationwide Availability
We have diagnostic branches across all major cities in the United States, including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to this advanced genetic testing regardless of your location.
Take Action Today
Don’t wait to get the critical genetic information you need for proper diagnosis and treatment planning. Our experienced team of molecular diagnostics specialists is ready to assist you with this important testing.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your INV(16)(p13q22) Gene Rearrangement Qualitative PCR Test. Early detection and accurate genetic characterization can make a significant difference in your treatment journey and overall outcomes.
Our dedicated customer service team is available to answer your questions, help with scheduling, and provide guidance on sample collection and transportation requirements. Take the first step toward comprehensive genetic assessment and personalized cancer care today.
