Interleukin 28B rs12979860 rs8099917 Genotyping Qualitative PCR Test
Understanding Interleukin 28B Genotyping
The Interleukin 28B (IL28B) Genotyping Qualitative PCR Test represents a breakthrough in personalized medicine for hepatitis C virus (HCV) treatment. This sophisticated genetic analysis examines specific variations in the IL28B gene, which plays a crucial role in the body’s immune response to viral infections. The test specifically targets two key single nucleotide polymorphisms (SNPs) – rs12979860 and rs8099917 – that have been scientifically proven to significantly influence treatment outcomes for HCV patients.
Interleukin-28B is a type III interferon lambda cytokine that activates the JAK-STAT signaling pathway, triggering antiviral responses. Genetic variations in the IL28B gene region can dramatically affect how individuals respond to interferon-based therapies, making this test an essential tool for optimizing hepatitis C treatment strategies.
What This Test Measures and Detects
This advanced molecular diagnostic test specifically identifies:
- rs12979860 Polymorphism: Determines whether you carry the CC, CT, or TT genotype
- rs8099917 Polymorphism: Identifies TT, TG, or GG genotype patterns
- Treatment Response Prediction: Assesses likelihood of achieving sustained virological response (SVR)
- Genetic Predisposition: Evaluates innate immune system capabilities against HCV
The test utilizes Real-Time PCR technology, providing highly accurate and reliable results for clinical decision-making. This method ensures precise detection of genetic variations that directly impact therapeutic outcomes.
Who Should Consider This Test
This genetic test is particularly valuable for individuals who:
- Have been diagnosed with chronic hepatitis C infection
- Are considering interferon-based treatment options
- Have experienced previous treatment failures
- Show elevated liver enzymes (ALT, AST) without clear cause
- Have family history of hepatitis C or liver disease
- Are undergoing evaluation for liver transplantation
- Experience unexplained fatigue, jaundice, or abdominal discomfort
Key Benefits of Interleukin 28B Genotyping
Personalized Treatment Planning
By understanding your genetic profile, healthcare providers can tailor hepatitis C treatment regimens to maximize effectiveness while minimizing side effects and treatment duration.
Improved Treatment Outcomes
Patients with favorable IL28B genotypes (CC for rs12979860) typically achieve higher sustained virological response rates, often exceeding 80% with standard therapy.
Cost-Effective Healthcare
Pre-treatment genetic testing helps avoid expensive, ineffective treatments for patients unlikely to respond, saving both financial resources and potential treatment-related complications.
Reduced Treatment Duration
For patients with favorable genotypes, treatment duration may be shortened, reducing overall medication exposure and improving quality of life during therapy.
Understanding Your Test Results
Your IL28B genotyping results will fall into specific categories that guide treatment decisions:
Favorable Genotype (CC for rs12979860)
Patients with this genotype typically demonstrate excellent response to interferon-based therapies, with high rates of sustained virological response. Treatment may be more effective and potentially shorter in duration.
Intermediate Response (CT for rs12979860)
This genotype shows moderate response rates to standard therapy. Your healthcare provider may consider extended treatment duration or combination therapies to optimize outcomes.
Poor Response (TT for rs12979860)
Patients with this genotype may have reduced response to interferon-based treatments. Alternative therapeutic approaches, including direct-acting antivirals, may be recommended for better outcomes.
It’s crucial to discuss your results with a qualified gastroenterologist or hepatologist who can interpret them in the context of your overall health, viral load, and liver condition.
Test Details and Pricing
| Test Information | Details |
|---|---|
| Test Name | Interleukin 28B rs12979860 rs8099917 Genotyping Qualitative PCR Test |
| Regular Price | $276 USD |
| Discount Price | $188 USD |
| Sample Type | 3 mL (2 mL min.) whole blood from 1 Lavender Top (EDTA) tube |
| Turnaround Time | Sample Thu / Mon by 9 am; Report Sat / Wed |
| Methodology | Real Time PCR |
| Preparation | No special preparation required |
Nationwide Availability
GGC DNA has testing facilities conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Take Control of Your Hepatitis C Treatment
Don’t leave your treatment response to chance. The Interleukin 28B Genotyping Test provides scientifically validated insights that can significantly improve your hepatitis C management strategy. With our special discounted price of only $188 USD (regularly $276), this valuable genetic information is more accessible than ever.
Ready to optimize your hepatitis C treatment plan? Call our dedicated healthcare team today at +1(267) 388-9828 to schedule your Interleukin 28B Genotyping Test. Our experienced staff will guide you through the simple testing process and help you take the first step toward personalized, effective hepatitis C treatment.
Book your appointment now and discover how genetic insights can transform your approach to hepatitis C management. Your journey to better treatment outcomes begins with a simple phone call.
