Immunophenotyping by Flow Cytometry Obstetric Panel
Comprehensive Introduction to Obstetric Immunophenotyping
The Immunophenotyping by Flow Cytometry Obstetric Panel represents a cutting-edge diagnostic approach in reproductive medicine, specifically designed to evaluate immune system function in women experiencing pregnancy-related challenges. This sophisticated test utilizes advanced flow cytometry technology to analyze specific immune cell populations that play critical roles in successful pregnancy maintenance and implantation.
Understanding immune system dynamics during pregnancy is essential because the maternal immune system undergoes complex adaptations to support fetal development while maintaining protection against pathogens. When these delicate immune balances are disrupted, it can lead to recurrent pregnancy loss, implantation failure, and other obstetric complications. Our specialized panel provides unprecedented insights into these immunological processes, enabling healthcare providers to make informed decisions about patient management and treatment strategies.
What This Test Measures and Detects
The Immunophenotyping by Flow Cytometry Obstetric Panel specifically analyzes key immune cell populations that are crucial for reproductive success:
Natural Killer (NK) Cells Analysis
- Quantifies uterine and peripheral NK cell populations
- Assesses NK cell activity and cytotoxicity levels
- Evaluates the balance between protective and harmful NK cell responses
- Identifies abnormal NK cell expansion that may threaten pregnancy
CD19 B-Cell Marker Assessment
- Measures B-cell populations and their activation status
- Evaluates antibody-producing cell lines
- Assesses autoimmune antibody production potential
- Identifies B-cell mediated immune responses affecting pregnancy
Who Should Consider This Test
This specialized immunophenotyping panel is particularly valuable for women experiencing:
Recurrent Pregnancy Loss
- Women with two or more consecutive pregnancy losses
- Patients with unexplained recurrent miscarriages
- Individuals with failed IVF cycles despite good embryo quality
Bad Obstetric History
- Patients with previous late pregnancy losses
- Women with autoimmune conditions affecting pregnancy
- Individuals with suspected immune-mediated infertility
- Patients with family history of autoimmune disorders
Specific Clinical Indications
- Unexplained infertility despite normal fertility workup
- Recurrent implantation failure in ART cycles
- Suspected immune system dysregulation
- Prior to considering immunological treatments
Significant Benefits of Immunophenotyping Testing
Precision Diagnosis
This test provides precise quantification of immune cell populations, enabling accurate diagnosis of immune system imbalances that may contribute to reproductive challenges. Unlike conventional testing methods, flow cytometry offers detailed cellular analysis with exceptional accuracy and reproducibility.
Personalized Treatment Planning
By identifying specific immune abnormalities, healthcare providers can develop targeted treatment strategies. This may include immunomodulatory therapies, specific medication regimens, or specialized protocols for assisted reproductive technologies.
Improved Pregnancy Outcomes
Understanding immune system function allows for interventions that can significantly improve pregnancy success rates. Many patients who receive appropriate immune-based treatments experience dramatically improved reproductive outcomes.
Comprehensive Reproductive Assessment
The test provides a complete immunological profile that complements other fertility evaluations, offering a more holistic understanding of reproductive health and potential barriers to successful pregnancy.
Understanding Your Test Results
Normal Immune Cell Ranges
Your results will include reference ranges for NK cells and CD19-positive B-cells. Normal ranges indicate balanced immune function compatible with successful pregnancy maintenance.
Elevated NK Cell Levels
Increased Natural Killer cell activity may suggest heightened immune responses that could interfere with embryo implantation or placental development. This finding often guides specific immunomodulatory treatments.
Abnormal B-Cell Populations
Alterations in CD19-positive B-cell populations may indicate autoimmune activity or abnormal antibody production that could affect pregnancy outcomes.
Clinical Correlation
It’s essential to interpret results in the context of your complete medical history and other diagnostic findings. Your healthcare provider will integrate these immunological findings with your overall clinical picture to develop the most appropriate management plan.
Follow-up Recommendations
Based on your results, your physician may recommend additional testing, specific treatments, or modified approaches to fertility management. Regular monitoring may be advised to track treatment response.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $188 |
| Regular Price | $250 |
| Test Name | Immunophenotyping by Flow Cytometry Obstetric Panel |
Sample Requirements and Processing
- Sample Type: 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube
- Shipping Instructions: Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE
- Turnaround Time: Sample Daily by 9 am; Report Same day
- Mandatory Requirement: Clinical history is mandatory for accurate interpretation
Nationwide Availability and Booking
GGC DNA maintains comprehensive diagnostic facilities across the United States, with specialized Flow Cytometry departments in all major metropolitan areas. Our expert team of gynecologists and immunology specialists ensures accurate testing and interpretation for patients nationwide.
We have conveniently located branches in:
- New York City and surrounding areas
- Los Angeles and Southern California
- Chicago and Midwest regions
- Houston and Texas locations
- Major cities throughout the USA
Book Your Test Today
Take the first step toward understanding your reproductive immunology profile. Our specialized Immunophenotyping by Flow Cytometry Obstetric Panel provides crucial insights that can help optimize your pregnancy outcomes. With same-day reporting and expert interpretation, you’ll receive comprehensive results to guide your reproductive journey.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your appointment or discuss your testing needs with our specialist team.
Our dedicated customer service representatives are available to answer your questions, explain the testing process, and help you coordinate sample collection at your nearest GGC DNA facility. Don’t let immune system concerns stand in the way of your reproductive goals – take control of your fertility journey with advanced immunological testing.
