Immunophenotyping by Flow Cytometry CD19 Test
Comprehensive Introduction to CD19 Immunophenotyping
Immunophenotyping by Flow Cytometry CD19 Test represents a cutting-edge diagnostic approach in modern hematology and oncology. This sophisticated laboratory technique utilizes advanced flow cytometry technology to precisely identify and characterize B-lymphocytes through their specific surface markers. The CD19 antigen serves as a crucial biomarker expressed on the surface of B-cells throughout their development, making it an essential target for detecting abnormalities in the immune system and diagnosing various hematological malignancies.
The importance of this test cannot be overstated in contemporary cancer diagnostics. By providing detailed information about B-cell populations, immunophenotyping enables healthcare providers to distinguish between normal and malignant cells, identify specific subtypes of blood cancers, and monitor treatment responses with unprecedented accuracy. This level of cellular analysis has revolutionized how oncologists approach diagnosis and management of hematological disorders.
What the CD19 Test Measures and Detects
The Immunophenotyping by Flow Cytometry CD19 Test specifically measures the presence and density of CD19 antigens on the surface of white blood cells. This comprehensive analysis provides critical information about:
- Quantification of CD19-positive B-cells in blood or bone marrow samples
- Identification of abnormal B-cell populations indicative of malignancies
- Detection of minimal residual disease following treatment
- Characterization of B-cell development stages and maturation patterns
- Assessment of immune system function and B-cell repertoire
This advanced diagnostic approach can detect various B-cell disorders including acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), non-Hodgkin lymphoma, and multiple myeloma. The test’s sensitivity allows for early detection of abnormal cell populations even when they represent a small percentage of total cells.
Who Should Consider CD19 Immunophenotyping
This specialized test is recommended for individuals presenting with specific clinical indications or symptoms that may suggest B-cell disorders. Consider CD19 immunophenotyping if you experience:
- Unexplained fatigue, weakness, or persistent fever
- Enlarged lymph nodes, spleen, or liver
- Unexplained weight loss or night sweats
- Frequent infections or unusual bleeding tendencies
- Abnormal complete blood count (CBC) results
- Bone pain or tenderness
- Family history of hematological malignancies
Patients undergoing treatment for B-cell malignancies should also consider regular CD19 testing to monitor treatment response and detect potential relapse. The test is particularly valuable for individuals diagnosed with or suspected of having B-cell lymphomas, leukemias, or other immune system disorders.
Significant Benefits of CD19 Testing
Undergoing CD19 immunophenotyping provides numerous clinical advantages for patients and healthcare providers alike:
- Accurate Diagnosis: Enables precise identification of specific B-cell malignancies
- Treatment Guidance: Helps oncologists select appropriate targeted therapies
- Disease Monitoring: Tracks treatment response and disease progression
- Early Detection: Identifies minimal residual disease before clinical symptoms appear
- Prognostic Information: Provides insights into disease aggressiveness and likely outcomes
- Personalized Medicine: Supports development of individualized treatment plans
Understanding Your Test Results
Interpreting CD19 immunophenotyping results requires specialized medical expertise, but general understanding can help patients engage more effectively in their care:
- Normal Results: Typically show appropriate CD19 expression on mature B-cells with normal distribution patterns
- Abnormal Patterns: May indicate presence of malignant B-cells, abnormal maturation, or immune deficiencies
- Quantitative Changes: Variations in CD19-positive cell percentages can suggest disease activity or treatment response
- Phenotypic Abnormalities: Unusual CD19 expression patterns may indicate specific subtypes of hematological malignancies
Your hematologist or oncologist will explain your specific results in the context of your clinical presentation, medical history, and other diagnostic findings. Regular monitoring through repeat testing provides valuable information about disease progression and treatment effectiveness.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $112 |
Sample Requirements and Processing
Turnaround Time: Sample collected daily by 9 AM; Report available same day
Sample Types:
- 3 mL (2 mL minimum) whole blood in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL minimum) whole blood in 1 Green Top (Sodium Heparin) tube
- OR 2 mL (1 mL minimum) Bone marrow in 1 Green Top (Sodium heparin) tube
Shipping Instructions: Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Specify time, date and clinical details on test request form.
Pre-test Instructions: Provide brief clinical history for accurate interpretation.
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with branches conveniently located in all major metropolitan areas. Our state-of-the-art flow cytometry laboratories ensure consistent, high-quality results regardless of your location. We serve patients in New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and numerous other cities nationwide.
Take Control of Your Health Today
Don’t wait to get the answers you need for proper diagnosis and treatment. The CD19 Immunophenotyping Test provides critical information that can significantly impact your healthcare journey. Our experienced team is ready to assist you with convenient scheduling, professional sample collection, and comprehensive result interpretation.
Ready to schedule your test? Contact us today at +1(267) 388-9828 or book your appointment online. Our dedicated healthcare professionals will guide you through the process and ensure you receive the highest quality diagnostic care available.
