Immunophenotyping by Flow Cytometry CD25 Test
Comprehensive Introduction to CD25 Immunophenotyping
Immunophenotyping by Flow Cytometry CD25 Test represents a cutting-edge diagnostic approach that provides detailed analysis of immune cell populations and their activation status. This sophisticated laboratory technique utilizes advanced flow cytometry technology to detect and quantify the CD25 surface marker, also known as the interleukin-2 receptor alpha chain. The test plays a crucial role in modern medical diagnostics by offering precise characterization of immune cell subsets, enabling healthcare providers to make informed decisions about patient care and treatment strategies.
What the CD25 Test Measures and Detects
The Immunophenotyping by Flow Cytometry CD25 Test specifically measures the expression of CD25 antigen on various immune cells, primarily focusing on:
- Activated T-lymphocytes and regulatory T-cells (Tregs)
- B-cell malignancies and lymphomas
- Acute and chronic leukemias with abnormal CD25 expression
- Autoimmune disease-related immune cell activation
- Transplant rejection monitoring through immune activation markers
Scientific Basis of CD25 Detection
CD25 serves as the alpha chain of the interleukin-2 receptor complex, playing a vital role in T-cell activation, proliferation, and immune regulation. Abnormal expression patterns can indicate various pathological conditions, including malignant transformations and autoimmune disorders. The flow cytometry methodology allows for simultaneous analysis of multiple cell surface markers, providing comprehensive immunophenotypic profiles that are essential for accurate diagnosis and classification of hematological malignancies.
Who Should Consider CD25 Immunophenotyping Testing
This advanced diagnostic test is recommended for individuals presenting with:
- Unexplained lymphadenopathy or enlarged lymph nodes
- Suspected T-cell or B-cell lymphomas
- Abnormal blood cell counts or unexplained cytopenias
- Autoimmune disorders with suspected immune dysregulation
- Monitoring of known hematological malignancies
- Post-transplant immune monitoring requirements
- Evaluation of immunodeficiency conditions
Clinical Indications and Symptoms
Patients experiencing persistent fatigue, unexplained weight loss, night sweats, recurrent infections, or abnormal bleeding tendencies should discuss CD25 testing with their hematologist or oncologist. The test is particularly valuable when conventional diagnostic methods provide inconclusive results or when precise immune cell characterization is necessary for treatment planning.
Benefits of CD25 Flow Cytometry Testing
- Precise Diagnosis: Enables accurate classification of lymphomas and leukemias
- Treatment Guidance: Helps determine appropriate targeted therapies
- Disease Monitoring: Tracks treatment response and disease progression
- Early Detection: Identifies abnormal immune cell populations before clinical symptoms worsen
- Personalized Medicine: Supports development of individualized treatment plans
- Rapid Results: Same-day reporting when samples are submitted by 9 AM
Understanding Your CD25 Test Results
Your CD25 immunophenotyping results will provide detailed information about immune cell populations and their activation status. Normal CD25 expression patterns vary depending on the specific cell type and clinical context. Elevated CD25 expression may indicate activated immune responses, autoimmune conditions, or certain malignancies. Reduced expression could suggest immune suppression or specific immunodeficiency states. Your healthcare provider will interpret these results in the context of your complete clinical picture, including symptoms, medical history, and other laboratory findings to develop an appropriate management plan.
Result Interpretation Guidelines
It’s essential to discuss your results with a qualified hematologist or oncologist who can provide comprehensive interpretation and recommend appropriate next steps based on the specific patterns observed in your immunophenotyping analysis.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunophenotyping by Flow Cytometry CD25 Test | $88 USD | $112 USD |
Sample Requirements and Processing
Turnaround Time: Sample Daily by 9 AM; Report Same Day
Sample Type: 3 mL (2 mL min.) whole blood in 1 Lavender Top (EDTA) tube AND 3 mL (2 mL min.) whole blood in 1 Green Top (Sodium Heparin) tube OR 2 mL (1 mL min.) Bone marrow in 1 Green Top (Sodium heparin) tube.
Shipping Instructions: Ship immediately at 18-22°C. DO NOT REFRIGERATE OR FREEZE. Specify time, date and clinical details on test request form.
Pre-test Instructions: Provide brief clinical history for optimal test interpretation.
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with branches conveniently located in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our nationwide network ensures that patients receive consistent, high-quality diagnostic services regardless of location.
Book Your CD25 Immunophenotyping Test Today
Take the first step toward comprehensive immune system analysis and precise diagnosis. Our experienced team of flow cytometry specialists and hematology experts are ready to provide you with accurate, timely results that can guide your healthcare journey. Contact us today to schedule your test and benefit from our same-day reporting capability.
Call or WhatsApp: +1(267) 388-9828
Our dedicated patient care coordinators are available to answer your questions, assist with scheduling, and provide guidance on sample collection and transportation requirements.
