Immunohistochemistry NKX3.1 Test: Advanced Prostate Cancer Marker Detection
Understanding the Immunohistochemistry NKX3.1 Test
The Immunohistochemistry NKX3.1 Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to detect the presence of the NKX3.1 protein marker in tissue samples. This highly specific test plays a crucial role in modern oncology by providing definitive identification of prostate tissue origin in various clinical scenarios. As a nuclear transcription factor expressed almost exclusively in prostate epithelium, NKX3.1 serves as an invaluable biomarker for distinguishing prostate cancer from other malignancies.
What Does the NKX3.1 Test Measure?
This specialized immunohistochemistry test specifically detects the NKX3.1 protein, which is:
- A prostate-specific homeobox gene product
- Expressed in both benign and malignant prostate tissue
- Highly specific for prostate epithelial cells
- Maintained in most prostate cancer cases, including high-grade tumors
Clinical Applications and Who Should Consider This Test
Primary Clinical Indications
The Immunohistochemistry NKX3.1 Test is particularly valuable for patients presenting with:
- Metastatic cancer of unknown primary origin
- Suspected prostate cancer metastases to distant sites
- Challenging prostate biopsy interpretations
- Differentiation of prostate cancer from other malignancies
- Evaluation of poorly differentiated tumors
Symptoms and Clinical Scenarios
Patients who may benefit from this testing include those with:
- Elevated PSA levels with ambiguous biopsy results
- Metastatic disease where prostate origin is suspected
- Previous inconclusive prostate cancer diagnoses
- Need for precise tissue origin confirmation in cancer staging
Key Benefits of NKX3.1 Immunohistochemistry Testing
Enhanced Diagnostic Accuracy
The NKX3.1 test provides superior specificity compared to traditional prostate markers, offering:
- Higher specificity than PSA for prostate tissue identification
- Reliable detection in both primary and metastatic prostate cancers
- Excellent performance in high-grade and treatment-resistant tumors
- Minimal cross-reactivity with non-prostate tissues
Clinical Decision Support
This test empowers healthcare providers with:
- Definitive confirmation of prostate cancer diagnosis
- Accurate identification of metastatic prostate cancer
- Guidance for appropriate treatment selection
- Improved patient stratification and prognosis assessment
Understanding Your Test Results
Interpretation Guidelines
Your NKX3.1 test results will be interpreted as follows:
- Positive Result: Nuclear staining indicates prostate origin, supporting prostate cancer diagnosis
- Negative Result: Absence of staining suggests non-prostate origin of the tumor
- Focal Staining: Limited positive areas may require correlation with clinical findings
- Intensity Grading: Staining intensity provides additional diagnostic information
Clinical Correlation
It’s important to understand that:
- Results should be interpreted in clinical context
- Correlation with other markers may be necessary
- Your physician will discuss implications for your treatment plan
- False positives are extremely rare due to high specificity
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry NKX3.1 Test | $88 USD | $112 USD |
Turnaround Time and Sample Requirements
Our testing service offers efficient processing with:
- Sample Acceptance: Daily by 6 PM
- Report Time: 3 days for tissue blocks, 5 days for small specimens
- Sample Type: Formalin fixed paraffin embedded tissue block or tissue in formalin
- Shipping: Room temperature with complete clinical history
Nationwide Testing Availability
We proudly serve patients across the United States with testing facilities in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified laboratories ensures consistent, high-quality testing standards nationwide.
Book Your Immunohistochemistry NKX3.1 Test Today
Take the next step in your cancer diagnosis journey with our specialized NKX3.1 testing service. Our experienced oncology team is ready to provide you with accurate, reliable results that can make a significant difference in your treatment planning.
Call or WhatsApp us now at +1(267) 388-9828 to schedule your test or speak with our genetic counseling specialists. We’re here to answer your questions and help you understand how this advanced testing can benefit your specific situation.
Don’t let diagnostic uncertainty delay your treatment decisions. With our affordable pricing at just $88 USD and rapid turnaround times, you can get the answers you need quickly and confidently. Trust General Genetics Corporation for your specialized cancer marker testing needs.
