Immunohistochemistry Vimentin Test: Comprehensive Cancer Diagnostic Analysis
Understanding the Immunohistochemistry Vimentin Test
The Immunohistochemistry Vimentin Test represents a cornerstone in modern cancer diagnostics, providing essential information for accurate tumor characterization and classification. This advanced laboratory technique utilizes specific antibodies to detect vimentin, a critical intermediate filament protein predominantly expressed in mesenchymal cells. As a fundamental component of the cellular cytoskeleton, vimentin plays vital roles in maintaining cell structure, facilitating intracellular transport, and supporting cellular migration processes.
This sophisticated diagnostic approach enables pathologists to distinguish between different tumor types with remarkable precision, particularly in cases where traditional histological examination proves insufficient. The test’s ability to identify mesenchymal differentiation patterns makes it invaluable for comprehensive cancer evaluation and treatment planning.
What Does the Vimentin Test Measure and Detect?
The Immunohistochemistry Vimentin Test specifically measures the presence and distribution of vimentin protein within tissue samples. This detection provides crucial diagnostic information including:
- Identification of mesenchymal cell origin in tumors
- Detection of sarcomas and other mesenchymal neoplasms
- Assessment of epithelial-mesenchymal transition in carcinomas
- Characterization of soft tissue tumors and their differentiation patterns
- Evaluation of tumor invasion and metastatic potential
- Distinction between carcinomas and sarcomas in challenging cases
Who Should Consider This Diagnostic Test?
The Immunohistochemistry Vimentin Test is recommended for patients presenting with specific clinical scenarios and diagnostic challenges:
Clinical Indications
- Patients with suspected soft tissue tumors or sarcomas
- Cases where tumor classification remains uncertain after initial pathology review
- Individuals with metastatic tumors of unknown primary origin
- Patients requiring comprehensive tumor characterization for treatment planning
- Cases involving differential diagnosis between carcinoma and sarcoma
- Evaluation of tumors showing spindle cell morphology
Symptoms and Clinical Presentations
- Unexplained masses or tumors in soft tissues
- Rapidly growing lesions requiring precise classification
- Metastatic disease with unknown primary tumor site
- Complex tumors requiring multi-marker analysis
- Cases where treatment decisions depend on accurate tumor typing
Significant Benefits of Vimentin Testing
Choosing the Immunohistochemistry Vimentin Test provides numerous advantages for both patients and healthcare providers:
Diagnostic Precision
- Enhanced accuracy in tumor classification and typing
- Improved differential diagnosis between similar-appearing tumors
- Comprehensive characterization of complex neoplasms
- Reliable identification of mesenchymal differentiation
Clinical Management Advantages
- Informed treatment planning based on precise tumor characteristics
- Better prediction of tumor behavior and potential outcomes
- Guidance for appropriate therapeutic interventions
- Support for personalized medicine approaches
Patient-Centered Benefits
- Reduced diagnostic uncertainty and anxiety
- Timely and accurate diagnosis leading to appropriate treatment
- Comprehensive understanding of tumor characteristics
- Peace of mind through definitive diagnostic information
Understanding Your Test Results
Interpreting Immunohistochemistry Vimentin Test results requires professional medical expertise, but understanding the general principles can help patients comprehend their diagnosis:
Positive Vimentin Expression
- Typically indicates mesenchymal origin or differentiation
- Common in sarcomas, some carcinomas with mesenchymal features
- May suggest epithelial-mesenchymal transition in certain tumors
- Helps confirm diagnosis of specific soft tissue neoplasms
Negative Vimentin Expression
- Often seen in pure epithelial tumors (carcinomas)
- May help exclude certain mesenchymal neoplasms
- Must be interpreted in context with other diagnostic markers
- Provides important exclusionary information in differential diagnosis
Pattern and Intensity Considerations
- Distribution pattern within tumor cells provides additional diagnostic clues
- Staining intensity may correlate with degree of differentiation
- Subcellular localization patterns offer valuable diagnostic information
- Results are always interpreted in clinical and histological context
Test Pricing and Availability
We are committed to making advanced diagnostic testing accessible and affordable for all patients across the United States.
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry Vimentin Test | $76 USD | $112 USD |
Turnaround Time
- Sample Acceptance: Daily by 6 PM
- Block Samples: 5 days
- Tissue Biopsy: 5 days
- Tissue Large Complex: 7 days
Sample Requirements
For optimal results, please provide:
- Tumor tissue in 10% formal-saline OR formalin fixed paraffin embedded block
- Ship at room temperature with proper packaging
- Include copy of Histopathology report
- Provide biopsy site information and complete clinical history
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our extensive network ensures that advanced diagnostic testing is accessible regardless of your location.
Take Control of Your Health Today
Don’t let diagnostic uncertainty delay your treatment journey. The Immunohistochemistry Vimentin Test provides the clarity and precision needed for effective cancer management. Our team of experienced pathologists and oncology specialists are ready to provide you with comprehensive diagnostic services and support.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your test or speak with our medical professionals about your diagnostic needs.
Early and accurate diagnosis is the foundation of successful cancer treatment. Trust our expertise and advanced diagnostic capabilities to provide you with the answers you need for your health journey.

