Immunohistochemistry Uroplakin III Test
Comprehensive Introduction to Uroplakin III Testing
The Immunohistochemistry Uroplakin III Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to detect urothelial malignancies with exceptional precision. This sophisticated laboratory technique utilizes specialized antibodies to identify uroplakin III proteins, which are crucial markers found in the umbrella cells of the urothelium – the specialized lining of the urinary tract.
At GGC DNA, we understand the critical importance of accurate cancer diagnosis. Our Immunohistochemistry Uroplakin III Test provides healthcare providers with definitive diagnostic information that directly impacts treatment decisions and patient outcomes. This test has become an essential tool in modern oncology practice, offering reliable differentiation between various urinary tract malignancies and helping to establish precise tumor classifications.
What Does the Uroplakin III Test Measure?
The Immunohistochemistry Uroplakin III Test specifically detects and visualizes the presence of uroplakin III proteins within tissue samples. Uroplakin III is a transmembrane protein exclusively expressed in the superficial umbrella cells of the urothelium, making it an ideal marker for identifying tumors of urothelial origin.
Key Detection Capabilities:
- Urothelial carcinoma identification and confirmation
- Differentiation between primary urothelial tumors and metastatic cancers
- Detection of transitional cell carcinoma variants
- Identification of poorly differentiated urothelial cancers
- Confirmation of urothelial origin in metastatic lesions
Who Should Consider This Test?
The Immunohistochemistry Uroplakin III Test is recommended for patients presenting with specific clinical indications and symptoms suggestive of urinary tract malignancies.
Clinical Indications Include:
- Patients with hematuria (blood in urine) of unknown origin
- Individuals with abnormal urinary cytology results
- Patients with bladder mass lesions detected during cystoscopy
- Cases where metastatic cancer of unknown primary origin is suspected
- Patients with previous history of urothelial carcinoma requiring monitoring
- Individuals with urinary tract obstruction or unexplained urinary symptoms
Significant Benefits of Uroplakin III Testing
Choosing the Immunohistochemistry Uroplakin III Test provides numerous advantages for both patients and healthcare providers in the diagnostic process.
Primary Benefits:
- Accurate Diagnosis: Provides definitive identification of urothelial origin in tumor samples
- Treatment Guidance: Helps oncologists develop targeted treatment strategies
- Early Detection: Enables identification of malignancies at earlier, more treatable stages
- Prognostic Information: Assists in determining disease progression and potential outcomes
- Therapeutic Planning: Guides decisions regarding surgical interventions and chemotherapy regimens
Understanding Your Test Results
Interpreting Immunohistochemistry Uroplakin III Test results requires professional medical expertise, but understanding the basic principles can help patients better comprehend their diagnosis.
Result Interpretation Guidelines:
- Positive Result: Indicates the presence of uroplakin III proteins, confirming urothelial origin of the tumor
- Negative Result: Suggests the tumor is unlikely to be of urothelial origin, prompting further investigation
- Focal Positivity: May indicate heterogeneous expression patterns in some tumor types
- Intensity Grading: The strength of staining can provide additional diagnostic information
It’s crucial to discuss your specific results with your healthcare provider, who will consider the immunohistochemistry findings alongside clinical history, imaging studies, and other diagnostic information to formulate a comprehensive treatment plan.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $112 |
Turnaround Time:
- Sample Acceptance: Daily by 6 PM
- Block Results: 5 days
- Tissue Biopsy Results: 5 days
- Tissue Large Complex Results: 7 days
Sample Requirements:
Submit tumor tissue in 10% formal-saline OR formalin fixed paraffin embedded block. Ship at room temperature. Please provide a copy of the histopathology report, site of biopsy, and complete clinical history.
Nationwide Availability and Booking
GGC DNA has diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities nationwide.
Our experienced team of pathologists and laboratory technicians ensures that every Immunohistochemistry Uroplakin III Test is performed with the highest standards of accuracy and precision. We work closely with referring physicians to provide comprehensive diagnostic support.
Ready to Schedule Your Test?
Take control of your health today. Book your Immunohistochemistry Uroplakin III Test by calling our dedicated healthcare line at +1(267) 388-9828 or schedule through our online booking system. Our patient care coordinators are available to answer your questions and assist with the scheduling process.
Early and accurate cancer detection can make a significant difference in treatment outcomes. Trust GGC DNA for reliable, advanced diagnostic testing that puts your health first.
