Immunohistochemistry SALL4 Test: Advanced Cancer Biomarker Detection
Understanding the SALL4 Immunohistochemistry Test
The Immunohistochemistry SALL4 Test represents a cutting-edge diagnostic approach in modern oncology and pathology. This specialized laboratory procedure detects the presence of SALL4 (Spalt-Like Transcription Factor 4) protein in tissue samples, serving as a crucial biomarker for various cancer types. SALL4 is a transcription factor that plays essential roles in embryonic development and stem cell maintenance, and its abnormal expression in adult tissues often indicates malignant transformation.
What Does the SALL4 Test Measure?
The Immunohistochemistry SALL4 Test specifically identifies and localizes the SALL4 protein within tissue samples using highly specific antibodies. This advanced technique provides:
- Detection of SALL4 protein expression patterns
- Localization of biomarker within specific cell types
- Semi-quantitative assessment of protein expression levels
- Correlation with tumor type and differentiation status
Clinical Applications and Who Should Consider This Test
Primary Clinical Indications
The SALL4 Immunohistochemistry Test is particularly valuable for patients with:
- Suspected germ cell tumors (testicular, ovarian, extragonadal)
- Liver masses requiring differentiation between hepatocellular carcinoma and other liver tumors
- Undifferentiated or poorly differentiated malignancies of unknown origin
- Gastrointestinal cancers requiring precise classification
- Metastatic tumors where primary site identification is challenging
Symptoms and Clinical Scenarios
Patients experiencing the following symptoms may benefit from SALL4 testing:
- Unexplained masses or tumors requiring precise classification
- Elevated tumor markers without clear primary tumor identification
- Complex liver lesions requiring accurate diagnosis
- Metastatic disease with unknown primary origin
- Recurrent or treatment-resistant cancers needing biomarker assessment
Key Benefits of SALL4 Immunohistochemistry Testing
Diagnostic Precision
The SALL4 test provides exceptional diagnostic accuracy in distinguishing between different tumor types, particularly in challenging cases where conventional histology may be inconclusive.
Treatment Guidance
By identifying specific biomarker expression patterns, the test helps oncologists tailor targeted treatment approaches and select appropriate therapeutic regimens based on molecular characteristics.
Prognostic Information
SALL4 expression patterns can provide valuable prognostic information, helping clinicians predict disease behavior and plan appropriate monitoring strategies.
Therapeutic Decision Support
The test results contribute significantly to treatment planning, including surgical approach decisions, chemotherapy selection, and radiation therapy considerations.
Understanding Your Test Results
Interpretation Guidelines
Your SALL4 Immunohistochemistry Test results will be interpreted by experienced pathologists and include:
- Positive Result: Indicates SALL4 protein expression, typically associated with specific tumor types including germ cell tumors and certain liver cancers
- Negative Result: Absence of detectable SALL4 protein, helping to rule out certain tumor types
- Pattern Analysis: Evaluation of staining intensity, distribution, and cellular localization
- Clinical Correlation: Integration with other diagnostic findings and clinical information
Next Steps After Testing
Your healthcare provider will discuss the results in the context of your overall clinical picture and develop an appropriate management plan based on the findings.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $112 |
Turnaround Time
- Sample Submission: Daily by 6 PM
- Block Samples: 5 days
- Tissue Biopsy: 5 days
- Complex Tissue Samples: 7 days
Sample Requirements
Submit tumor tissue in 10% formal-saline OR formalin-fixed paraffin-embedded block. Ship at room temperature. Please provide a copy of the histopathology report, site of biopsy, and complete clinical history.
Nationwide Availability
GGC DNA Diagnostics has branches across the United States, serving patients in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network of certified laboratories ensures consistent, high-quality testing nationwide.
Book Your SALL4 Immunohistochemistry Test Today
Take the next step in your diagnostic journey with confidence. Our team of experienced oncologists and pathologists are ready to provide you with the precise diagnostic information you need. Call us today at +1(267) 388-9828 to schedule your SALL4 Immunohistochemistry Test or to speak with our genetic counseling specialists about your testing options.
Why Choose GGC DNA Diagnostics?
- Board-certified pathologists and oncologists
- State-of-the-art immunohistochemistry laboratory
- Rapid turnaround times with guaranteed quality
- Comprehensive genetic counseling services
- Nationwide network of testing facilities
- Insurance coordination and payment plans available
