Immunohistochemistry LMO2 Test
Understanding the Immunohistochemistry LMO2 Test
The Immunohistochemistry LMO2 Test represents a cutting-edge diagnostic approach in cancer pathology, specifically designed to detect the LIM Domain Only 2 (LMO2) protein expression in tissue samples. This sophisticated immunohistochemical analysis plays a pivotal role in modern oncology by providing precise molecular characterization of lymphoid malignancies. The test utilizes specialized antibodies that bind specifically to LMO2 proteins, allowing pathologists to visualize and quantify their presence within tumor cells through microscopic examination.
LMO2 is a crucial transcriptional regulator involved in hematopoietic development and has emerged as a significant biomarker in lymphoma diagnosis. Its detection helps distinguish between various subtypes of B-cell lymphomas, particularly in cases where traditional histopathological examination may yield ambiguous results. The test’s importance lies in its ability to provide objective, reproducible data that complements conventional diagnostic methods, ultimately leading to more accurate cancer classification and personalized treatment strategies.
What the LMO2 Test Measures and Detects
The Immunohistochemistry LMO2 Test specifically measures the presence and distribution of LMO2 protein within tissue specimens. This protein serves as a critical biomarker for:
- Identification of germinal center B-cell-like (GCB) subtype in diffuse large B-cell lymphoma (DLBCL)
- Differentiation between various B-cell lymphoma subtypes
- Assessment of tumor cell origin and differentiation state
- Evaluation of prognostic markers in lymphoid malignancies
- Detection of specific protein expression patterns that influence treatment response
The test employs advanced immunohistochemical techniques where tissue sections are treated with specific anti-LMO2 antibodies. These antibodies bind to LMO2 proteins present in the sample, and subsequent staining reactions make the bound antibodies visible under microscopy. The intensity and pattern of staining provide valuable information about the tumor’s biological characteristics and potential behavior.
Who Should Consider the LMO2 Test
This specialized diagnostic test is particularly important for patients presenting with:
- Suspected or confirmed lymphoma cases requiring precise subtyping
- Unexplained lymph node enlargement or systemic symptoms
- Cases where initial pathology results are inconclusive or ambiguous
- Patients with B-cell malignancies needing comprehensive molecular profiling
- Individuals requiring prognostic assessment for treatment planning
- Cases where traditional histology cannot definitively classify lymphoma subtype
- Patients being evaluated for targeted therapy options
Oncologists typically recommend this test when additional molecular characterization is necessary to guide treatment decisions, especially in cases of diffuse large B-cell lymphoma where LMO2 expression helps determine the appropriate therapeutic approach.
Benefits of Taking the Immunohistochemistry LMO2 Test
Choosing the LMO2 test provides numerous advantages for both patients and healthcare providers:
- Precise Diagnosis: Enables accurate classification of lymphoma subtypes beyond conventional microscopy
- Treatment Guidance: Helps oncologists select the most appropriate treatment regimens based on molecular characteristics
- Prognostic Information: Provides valuable insights into disease behavior and potential outcomes
- Personalized Medicine: Supports the development of tailored treatment approaches
- Comprehensive Assessment: Complements other diagnostic methods for a complete clinical picture
- Objective Results: Delivers reproducible, standardized data for consistent interpretation
- Advanced Technology: Utilizes state-of-the-art immunohistochemical techniques
Understanding Your Test Results
Interpreting LMO2 test results requires specialized expertise from trained pathologists. The findings typically include:
- Positive Staining: Indicates the presence of LMO2 protein, often associated with germinal center B-cell origin in DLBCL
- Negative Staining: Suggests absence of LMO2 expression, which may indicate different lymphoma subtypes
- Staining Intensity: The strength of staining can provide additional prognostic information
- Pattern Distribution: The cellular localization and distribution pattern of staining
Your healthcare provider will explain how these results relate to your specific condition and treatment options. Positive LMO2 staining in DLBCL typically correlates with the germinal center B-cell-like subtype, which may have different treatment responses and prognosis compared to other subtypes. It’s essential to discuss your results thoroughly with your oncologist to understand their implications for your treatment plan.
Test Pricing and Availability
| Test Description | Price |
|---|---|
| Immunohistochemistry LMO2 Test – Discount Price | $88 USD |
| Immunohistochemistry LMO2 Test – Regular Price | $112 USD |
Turnaround Time
- Sample Acceptance: Daily by 6 PM
- Report Timeline: Block – 5 days | Tissue Biopsy – 5 days | Tissue Large Complex – 7 days
Sample Requirements
Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Nationwide Availability
GGC DNA has branches across the United States, making the Immunohistochemistry LMO2 Test accessible to patients in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our nationwide network ensures that advanced cancer diagnostics are available wherever you are located.
Book Your Test Today
Take the next step in your cancer diagnosis and treatment planning. Our experienced team is ready to assist you with scheduling your Immunohistochemistry LMO2 Test. Contact us today to discuss your testing needs and arrange for sample collection or drop-off.
Call or WhatsApp: +1(267) 388-9828
Our dedicated customer service representatives will guide you through the process, answer any questions you may have, and help you schedule your test at your convenience. Don’t wait to get the precise diagnostic information you need for optimal cancer care.
