Immunohistochemistry LECT2 Test: Advanced Amyloidosis Diagnosis
Understanding the Immunohistochemistry LECT2 Test
The Immunohistochemistry LECT2 Test represents a cutting-edge diagnostic approach for detecting leukocyte cell-derived chemotaxin 2 (LECT2) amyloidosis, a specific subtype of systemic amyloid deposition disease. This sophisticated laboratory technique utilizes specialized antibodies to identify and localize LECT2 protein aggregates within tissue samples, providing clinicians with definitive diagnostic information that guides treatment decisions and patient management strategies.
LECT2 amyloidosis represents a distinct clinical entity characterized by the abnormal accumulation of LECT2 protein fibrils in various organs, most commonly affecting renal and hepatic tissues. Unlike other forms of amyloidosis, LECT2-related disease often presents with unique clinical features and requires specialized diagnostic confirmation through immunohistochemical methods.
What the Immunohistochemistry LECT2 Test Detects
This advanced diagnostic test specifically identifies and characterizes:
- LECT2 protein deposits in tissue biopsies
- Amyloid fibril formation patterns
- Tissue distribution and burden of LECT2 amyloid
- Organ-specific involvement patterns
- Co-existing amyloid types through differential staining
The test employs highly specific monoclonal antibodies that bind exclusively to LECT2 amyloid proteins, creating visible staining patterns that pathologists can interpret to confirm diagnosis and assess disease severity.
Who Should Consider LECT2 Immunohistochemistry Testing
Clinical Indications and Symptoms
Patients presenting with the following clinical scenarios should consider LECT2 immunohistochemistry testing:
- Unexplained renal impairment with proteinuria
- Chronic kidney disease of unknown etiology
- Hepatic dysfunction with suspected amyloid involvement
- Family history of amyloidosis or renal disease
- Previous negative amyloid subtyping results
- Patients of Mexican or Native American descent with renal issues
- Suspected systemic amyloidosis with atypical presentation
Specialist Recommendations
This test is particularly valuable for nephrologists and physicians managing patients with:
- Progressive renal failure without clear cause
- Nephrotic syndrome presentation
- Liver enlargement with renal involvement
- Patients requiring definitive amyloid subtyping
Benefits of LECT2 Immunohistochemistry Testing
Choosing the Immunohistochemistry LECT2 Test provides numerous clinical advantages:
- Definitive Diagnosis: Provides conclusive evidence of LECT2 amyloidosis
- Treatment Guidance: Informs appropriate therapeutic approaches
- Prognostic Information: Helps predict disease progression and outcomes
- Family Screening: Enables genetic counseling and family member evaluation
- Differential Diagnosis: Distinguishes LECT2 from other amyloid types
- Monitoring Capability: Allows assessment of treatment response
Understanding Your Test Results
Interpretation Guidelines
Your LECT2 immunohistochemistry results will typically fall into one of these categories:
Positive Result
A positive result indicates the presence of LECT2 amyloid deposits in the examined tissue. This confirms the diagnosis of LECT2 amyloidosis and should prompt:
- Comprehensive renal and hepatic function assessment
- Consultation with a nephrologist or amyloid specialist
- Discussion of management strategies and treatment options
- Consideration of family member screening
Negative Result
A negative result suggests the absence of detectable LECT2 amyloid deposits. This may indicate:
- Alternative forms of amyloidosis requiring different testing
- Non-amyloid related kidney or liver disease
- Need for additional diagnostic evaluation
- Consideration of other amyloid subtyping methods
Equivocal Result
In some cases, results may be inconclusive, requiring:
- Repeat testing with additional tissue samples
- Correlation with clinical findings
- Consideration of alternative diagnostic approaches
- Expert pathological consultation
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry LECT2 Test | $46 USD | $52 USD |
Turnaround Time
- Sample Acceptance: Daily by 6 PM
- Block Processing: 5 days
- Tissue Biopsy: 5 days
- Large Complex Tissue: 7 days
Sample Requirements
Submit tumor tissue in 10% formal-saline OR formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Nationwide Testing Availability
We have diagnostic branches conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many other cities. Our nationwide network ensures accessible, high-quality diagnostic services for patients throughout the country.
Take Action for Your Health
Don’t let unexplained symptoms go undiagnosed. The Immunohistochemistry LECT2 Test provides the clarity needed for proper diagnosis and treatment planning. Our experienced team is ready to assist you with comprehensive testing and expert interpretation.
Book your Immunohistochemistry LECT2 Test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment online. Take the first step toward accurate diagnosis and effective management of amyloid-related conditions.
Our commitment to excellence in diagnostic medicine ensures you receive the highest quality testing with rapid turnaround times and comprehensive result interpretation. Trust General Genetics Corporation for your specialized diagnostic needs.
