Immunohistochemistry Glycophorin A Test
Understanding the Immunohistochemistry Glycophorin A Test
The Immunohistochemistry Glycophorin A Test represents a cutting-edge diagnostic approach in modern pathology and oncology. This specialized laboratory technique utilizes advanced immunohistochemical staining methods to detect glycophorin A, a critical transmembrane protein predominantly expressed in erythroid cells and their precursors. As a fundamental component of red blood cell membranes, glycophorin A serves as an essential marker for identifying and characterizing various hematological disorders and malignancies.
This sophisticated diagnostic tool has revolutionized the way pathologists and oncologists approach the diagnosis of blood-related cancers and bone marrow disorders. By providing precise cellular localization and quantification of glycophorin A expression, the test offers invaluable insights into abnormal erythroid development patterns that traditional hematological examinations might miss.
What the Test Measures and Detects
The Immunohistochemistry Glycophorin A Test specifically identifies and quantifies the presence of glycophorin A protein in tissue samples. This membrane sialoglycoprotein is exclusively expressed in erythroid lineage cells, making it an ideal marker for:
- Detection of erythroid precursors in bone marrow biopsies
- Identification of abnormal red blood cell development patterns
- Differentiation between various types of leukemia
- Assessment of bone marrow involvement in hematological malignancies
- Monitoring treatment response in erythroid disorders
The test employs highly specific antibodies that bind to glycophorin A antigens, creating visible staining patterns that pathologists can analyze under microscopy. This allows for precise localization of erythroid cells within tissue architecture, providing crucial diagnostic information beyond what conventional staining methods can offer.
Who Should Consider This Test
The Immunohistochemistry Glycophorin A Test is recommended for patients presenting with specific clinical indications and symptoms suggestive of hematological disorders:
Clinical Indications:
- Unexplained anemia that doesn’t respond to conventional treatments
- Abnormal blood cell counts requiring further investigation
- Suspected bone marrow disorders or malignancies
- Evaluation of possible erythroleukemia or other erythroid neoplasms
- Monitoring patients with known hematological conditions
- Differentiation between various types of myelodysplastic syndromes
Symptoms That May Warrant Testing:
- Persistent fatigue and weakness
- Unexplained bruising or bleeding
- Recurrent infections
- Bone pain or tenderness
- Enlarged lymph nodes or spleen
- Unexplained weight loss
- Night sweats and fever
Benefits of Taking the Immunohistochemistry Glycophorin A Test
Choosing the Immunohistochemistry Glycophorin A Test provides numerous advantages for accurate diagnosis and effective treatment planning:
- Precise Diagnosis: Enables accurate identification of erythroid lineage disorders with high specificity
- Early Detection: Facilitates early identification of hematological malignancies before they progress
- Treatment Guidance: Provides critical information for developing targeted treatment strategies
- Prognostic Value: Helps assess disease severity and predict treatment outcomes
- Minimally Invasive: Utilizes existing tissue samples, reducing the need for additional procedures
- Comprehensive Analysis: Offers detailed cellular-level insights beyond standard blood tests
Understanding Your Test Results
Interpreting Immunohistochemistry Glycophorin A Test results requires specialized expertise from our board-certified pathologists. Here’s a general guide to understanding your findings:
Positive Results:
- Strong staining indicates normal or increased erythroid activity
- Pattern and intensity help differentiate between benign and malignant conditions
- Specific staining patterns may suggest particular types of erythroid disorders
Negative Results:
- Absence of staining may indicate non-erythroid lineage malignancies
- Helps rule out certain types of blood cancers
- Provides valuable exclusionary information for differential diagnosis
Interpretation Considerations:
- Results are interpreted in clinical context with other laboratory findings
- Staining intensity and distribution patterns are carefully evaluated
- Correlation with patient symptoms and other test results is essential
- Our expert pathologists provide comprehensive analysis and recommendations
Test Pricing and Availability
| Test Description | Regular Price | Discount Price |
|---|---|---|
| Immunohistochemistry Glycophorin A Test | $112 USD | $88 USD |
Turnaround Time:
- Sample Collection: Daily by 6 PM
- Block Processing: 5 days
- Tissue Biopsy: 5 days
- Tissue Large Complex: 7 days
Sample Requirements:
Submit tumor tissue in 10% formal-saline OR formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history.
Nationwide Availability
GGC DNA has branches across all major cities in the United States, ensuring convenient access to this advanced diagnostic testing. Our state-of-the-art facilities in New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose provide consistent, high-quality testing services with rapid turnaround times.
Book Your Test Today
Take the first step toward accurate diagnosis and effective treatment. Our specialized team of oncologists and pathologists is ready to provide you with comprehensive diagnostic services and personalized care.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your Immunohistochemistry Glycophorin A Test and receive professional guidance from our expert medical team.
Don’t wait to get the answers you need for proper diagnosis and treatment planning. Our compassionate staff will guide you through the testing process and ensure you receive the highest quality care at our conveniently located facilities nationwide.
