Immunohistochemistry Cytokeratin 19 CK19 Test
Comprehensive Introduction to CK19 Testing
The Immunohistochemistry Cytokeratin 19 (CK19) Test represents a sophisticated diagnostic approach in modern pathology, utilizing advanced immunohistochemical techniques to detect specific protein markers in tissue samples. This specialized test plays a crucial role in cancer diagnosis and classification, providing healthcare providers with essential information for developing targeted treatment strategies.
What is Cytokeratin 19?
Cytokeratin 19 is a type I intermediate filament protein expressed in various epithelial tissues throughout the body. As one of the smallest cytokeratins, CK19 serves as a reliable marker for epithelial differentiation and is particularly valuable in identifying carcinomas and their metastatic deposits.
What the Test Measures and Detects
The Immunohistochemistry CK19 Test specifically identifies the presence and distribution of cytokeratin 19 protein within tissue samples through advanced staining techniques. This test provides critical diagnostic information including:
- Detection of epithelial differentiation in tumors
- Identification of carcinoma cells in various tissue types
- Confirmation of metastatic carcinoma origins
- Assessment of tumor margins and surgical resection completeness
- Differentiation between carcinoma and other tumor types
Who Should Consider This Test
This specialized diagnostic test is recommended for patients presenting with:
- Suspected carcinoma based on clinical findings
- Undifferentiated tumors requiring precise classification
- Metastatic tumors of unknown primary origin
- Previous inconclusive biopsy results
- Monitoring treatment response in known carcinomas
- Evaluation of surgical margins following tumor resection
Clinical Indications
The CK19 test is particularly valuable in cases involving breast cancer, lung cancer, gastrointestinal malignancies, and head and neck cancers. It helps oncologists and pathologists make accurate diagnoses when traditional histopathological examination alone may be insufficient.
Benefits of Taking the CK19 Test
Choosing the Immunohistochemistry CK19 Test provides numerous advantages for both patients and healthcare providers:
- Accurate Diagnosis: Provides definitive identification of epithelial-derived tumors
- Treatment Guidance: Helps oncologists develop targeted treatment plans
- Prognostic Information: Offers insights into disease progression and outcomes
- Metastasis Detection: Identifies metastatic deposits and their origins
- Surgical Planning: Assists in determining appropriate surgical margins
- Cost-Effective: Affordable testing at only $88 USD
Understanding Your Test Results
Interpreting CK19 test results requires professional medical expertise, but here’s general guidance on what your results may indicate:
Positive CK19 Staining
A positive result typically indicates the presence of epithelial-derived cells, suggesting carcinoma. The pattern and intensity of staining provide additional information about the tumor characteristics and help pathologists classify the specific type of carcinoma present.
Negative CK19 Staining
A negative result generally indicates the absence of epithelial differentiation, which may suggest non-epithelial tumors such as sarcomas, lymphomas, or melanomas. However, some carcinomas may show variable CK19 expression, so results must be interpreted in clinical context.
Interpretation by Specialists
Your results will be carefully analyzed by board-certified pathologists who consider the staining pattern, intensity, and distribution in conjunction with clinical history and other diagnostic findings to provide a comprehensive assessment.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry Cytokeratin 19 CK19 Test | $88 USD | $126 USD |
Turnaround Time
- Sample Submission: Daily by 6 PM
- Block Processing: 5 days
- Tissue Biopsy: 5 days
- Complex Tissue Samples: 7 days
Sample Requirements
For accurate testing, please provide:
- Tumor tissue preserved in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Ship samples at room temperature
- Include complete clinical history
- Provide biopsy site information
- Submit a copy of the histopathology report
Nationwide Availability
GGC DNA maintains comprehensive testing facilities across the United States, with convenient locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our extensive network ensures timely sample processing and result delivery regardless of your location.
Book Your Test Today
Take the first step toward accurate cancer diagnosis and personalized treatment planning. Our team of experienced pathologists and oncologists are ready to provide you with the highest quality diagnostic services.
Call or WhatsApp us today at +1(267) 388-9828 to schedule your Immunohistochemistry Cytokeratin 19 CK19 Test. Our knowledgeable staff will guide you through the process, answer any questions, and help arrange convenient testing at one of our nationwide locations.
Don’t wait for uncertainty – get the definitive answers you need for proper diagnosis and treatment. Contact GGC DNA now and take control of your health journey with confidence and clarity.
