Immunohistochemistry CD45 RO Pan T Test
Comprehensive Introduction to CD45 RO Pan T Testing
The Immunohistochemistry CD45 RO Pan T Test represents a cornerstone in modern cancer diagnostics, specifically designed to identify and characterize T-lymphocytes within tissue specimens. This sophisticated laboratory technique utilizes specialized antibodies that target the CD45 RO antigen, a marker predominantly expressed on memory T-cells and activated T-lymphocytes. As an essential component of comprehensive cancer evaluation, this test provides invaluable insights into the immune microenvironment of tumors and helps distinguish between various types of lymphoid malignancies.
Immunohistochemistry has revolutionized cancer diagnosis by enabling pathologists to visualize specific cellular markers directly within tissue architecture. The CD45 RO Pan T Test specifically focuses on T-cell populations, which play critical roles in immune surveillance and can become malignant in conditions like T-cell lymphomas. By precisely identifying these cells, healthcare providers can make more accurate diagnoses and develop targeted treatment strategies.
What the CD45 RO Pan T Test Measures and Detects
This advanced diagnostic test specifically targets and identifies:
- T-Lymphocyte Identification: Detects the presence and distribution of T-cells within tissue samples
- CD45 RO Expression: Measures the expression levels of CD45 RO antigen on cell surfaces
- Memory T-Cell Populations: Identifies subsets of memory T-cells involved in long-term immunity
- T-Cell Malignancies: Helps diagnose various T-cell lymphomas and leukemias
- Immune Cell Infiltration: Assesses the degree of T-cell infiltration in tumor microenvironments
Who Should Consider the CD45 RO Pan T Test
This specialized test is particularly important for individuals presenting with:
- Unexplained lymph node enlargement or swelling
- Suspected lymphoma based on clinical presentation
- Abnormal blood cell counts suggesting hematological malignancy
- Previous inconclusive biopsy results requiring further characterization
- Monitoring of known T-cell disorders or malignancies
- Evaluation of immune system disorders affecting T-cell function
Clinical Indications and Symptoms
Patients experiencing persistent symptoms such as unexplained fever, night sweats, weight loss, fatigue, or multiple enlarged lymph nodes should discuss this testing option with their healthcare provider. The test is particularly valuable when initial evaluations suggest possible lymphoid malignancies but require definitive characterization.
Significant Benefits of CD45 RO Pan T Testing
- Precise Diagnosis: Enables accurate classification of lymphoid malignancies
- Treatment Guidance: Provides critical information for selecting appropriate therapies
- Prognostic Information: Helps predict disease course and treatment response
- Minimized Misdiagnosis: Reduces the risk of incorrect cancer classification
- Personalized Medicine: Supports development of targeted treatment approaches
- Comprehensive Evaluation: Complements other diagnostic methods for complete assessment
Understanding Your Test Results
Your CD45 RO Pan T Test results will be interpreted by experienced pathologists and oncologists. Positive staining for CD45 RO indicates the presence of T-lymphocytes, which can have different implications depending on the clinical context:
Interpretation Guidelines
- Strong Positive Staining: Typically indicates significant T-cell presence, potentially suggesting T-cell lymphoma or reactive T-cell populations
- Focal Positive Staining: May represent localized T-cell infiltration in specific tissue areas
- Negative Staining: Suggests absence of T-cells, which might indicate B-cell malignancies or other conditions
- Pattern Analysis: The distribution and pattern of staining provide additional diagnostic information
It’s essential to discuss your results with your healthcare provider, who will consider the findings in the context of your complete clinical picture, including symptoms, physical examination findings, and other test results.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $76 |
| Regular Price | $112 |
Turnaround Time and Sample Requirements
- Standard Block Processing: 5 days
- Tissue Biopsy Analysis: 5 days
- Large Complex Tissue: 7 days
- Sample Submission: Daily by 6 PM
Sample Type: Submit tumor tissue in 10% formal-saline OR formalin-fixed paraffin-embedded block. Ship at room temperature. Provide a copy of the histopathology report, site of biopsy, and clinical history.
Nationwide Accessibility and Booking
We maintain diagnostic facilities across the United States, including major metropolitan areas such as New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures convenient access to this essential diagnostic service regardless of your location.
For immediate scheduling or to discuss your testing needs with our specialist team, contact us at +1(267) 388-9828 or book your appointment through our online portal. Our dedicated staff will guide you through the sample submission process and answer any questions about the CD45 RO Pan T Test.
Why Choose Our Diagnostic Services?
- Board-certified pathologists and oncologists
- State-of-the-art immunohistochemistry technology
- Rapid turnaround times with guaranteed accuracy
- Comprehensive result interpretation and reporting
- Nationwide network of accredited laboratories
- Insurance coordination and billing assistance
Take the next step toward accurate diagnosis and effective treatment planning. Schedule your Immunohistochemistry CD45 RO Pan T Test today and benefit from our expertise in cancer diagnostics and personalized patient care.
