Immunohistochemistry CD20 Test: Comprehensive Cancer Biomarker Detection
Understanding the Immunohistochemistry CD20 Test
The Immunohistochemistry CD20 Test represents a cornerstone in modern cancer diagnostics, specifically designed to detect the presence of CD20 antigen on B-cell surfaces. This sophisticated laboratory technique utilizes specialized antibodies that bind specifically to the CD20 protein, creating visible staining patterns that pathologists can analyze under microscopy. The test’s precision in identifying B-cell lineage makes it indispensable for accurate lymphoma classification and treatment planning.
CD20 is a transmembrane protein expressed exclusively on B-cells during specific developmental stages, making it an ideal marker for distinguishing B-cell malignancies from other types of cancers. The test’s clinical significance extends beyond mere detection—it provides critical information that directly influences therapeutic decisions, particularly regarding targeted monoclonal antibody treatments.
What the CD20 Test Measures and Detects
The Immunohistochemistry CD20 Test specifically identifies and quantifies the presence of CD20 protein expression in tissue samples. This advanced diagnostic tool provides:
- Detection of B-cell lineage in lymphoid tissues
- Identification of CD20-positive B-cell lymphomas
- Differentiation between B-cell and T-cell malignancies
- Assessment of CD20 expression levels for treatment planning
- Confirmation of B-cell origin in uncertain cases
The test’s sensitivity allows for precise localization of CD20 expression within tissue architecture, providing valuable insights into tumor microenvironment and cellular distribution patterns that influence disease progression and treatment response.
Who Should Consider the CD20 Test
This specialized diagnostic test is recommended for patients presenting with:
- Unexplained lymph node enlargement or swelling
- Suspected lymphoma based on clinical presentation
- Abnormal blood counts suggesting hematological malignancy
- Previous diagnosis requiring confirmation of B-cell origin
- Need for treatment planning with targeted therapies
- Monitoring treatment response in CD20-positive malignancies
- Unexplained fever, night sweats, or weight loss with lymphadenopathy
Clinical Benefits of CD20 Testing
Undergoing the Immunohistochemistry CD20 Test provides numerous clinical advantages:
- Precise Diagnosis: Accurate identification of B-cell lymphoma subtypes
- Treatment Guidance: Essential for selecting appropriate monoclonal antibody therapies
- Prognostic Information: CD20 expression levels correlate with treatment outcomes
- Therapeutic Monitoring: Track treatment effectiveness and disease progression
- Personalized Medicine: Enables targeted treatment approaches
- Reduced Misdiagnosis: Minimizes incorrect lymphoma classification
Understanding Your Test Results
Your CD20 test results will be interpreted by experienced pathologists and oncologists:
- CD20 Positive: Indicates presence of B-cell lymphoma, making patients candidates for CD20-targeted therapies
- CD20 Negative: Suggests absence of CD20 expression, requiring alternative diagnostic approaches
- Variable Expression: May indicate heterogeneous tumor populations requiring comprehensive evaluation
- Clinical Correlation: Results are interpreted in context with other diagnostic findings and clinical presentation
Your healthcare provider will discuss the implications of your results and develop an appropriate treatment plan based on the comprehensive diagnostic picture.
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| Immunohistochemistry CD20 Test – Discount Price | $76 |
| Immunohistochemistry CD20 Test – Regular Price | $112 |
Turnaround Time and Sample Requirements
Our laboratory maintains efficient processing to ensure timely results:
- Sample Submission: Daily by 6 PM
- Report Timeline: Tissue Block – 5 days | Tissue Biopsy – 5 days | Complex Tissue – 7 days
- Sample Type: Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block
- Shipping: Room temperature transport
- Required Documentation: Histopathology report, biopsy site information, and clinical history
Nationwide Accessibility
General Genetics Corporation provides comprehensive diagnostic services across the United States with branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and numerous other locations. Our network ensures convenient access to advanced cancer diagnostics regardless of your location.
Take Control of Your Health Today
Early and accurate diagnosis is crucial for successful cancer treatment outcomes. The Immunohistochemistry CD20 Test provides the critical information needed for precise lymphoma classification and targeted treatment planning. Don’t delay in obtaining the diagnostic clarity you need for optimal healthcare decisions.
Book your Immunohistochemistry CD20 Test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment through our online booking system. Our experienced team is ready to assist you with comprehensive diagnostic services and personalized care.
