Immunohistochemistry CD117 Test: Advanced Cancer Diagnosis
Understanding the Immunohistochemistry CD117 Test
The Immunohistochemistry CD117 Test represents a cutting-edge diagnostic approach in modern oncology, utilizing specialized antibodies to detect the presence of CD117 (c-KIT) protein markers in tissue specimens. This sophisticated laboratory technique provides critical insights into cellular composition and protein expression patterns that are essential for accurate cancer diagnosis and classification.
What Does the CD117 Test Measure?
The Immunohistochemistry CD117 Test specifically identifies and measures the expression of CD117 antigens, which are transmembrane receptor tyrosine kinases primarily associated with:
- Gastrointestinal stromal tumors (GIST) – the most common mesenchymal tumors of the gastrointestinal tract
- Mast cell disorders including systemic mastocytosis
- Certain types of melanoma and seminomas
- Acute myeloid leukemia in specific subtypes
- Other rare tumors expressing c-KIT receptors
Who Should Consider This Test?
This specialized diagnostic test is recommended for patients presenting with:
- Suspected gastrointestinal tumors or masses identified through imaging studies
- Unexplained abdominal pain, gastrointestinal bleeding, or obstruction symptoms
- Skin lesions suggestive of mast cell disorders or systemic mastocytosis
- Previously diagnosed tumors requiring precise classification for treatment planning
- Patients with family history of GIST or related cancer syndromes
- Individuals undergoing evaluation for targeted therapy eligibility
Clinical Benefits of CD117 Testing
Choosing the Immunohistochemistry CD117 Test provides numerous advantages for both patients and healthcare providers:
- Accurate Diagnosis: Enables precise identification of CD117-positive tumors, particularly crucial for GIST diagnosis
- Treatment Guidance: Results directly influence treatment decisions, especially for targeted therapies like imatinib
- Prognostic Information: CD117 expression patterns can provide valuable prognostic insights
- Therapeutic Monitoring: Helps assess treatment response and disease progression
- Minimally Invasive: Utilizes existing biopsy specimens without requiring additional procedures
Understanding Your Test Results
Your Immunohistochemistry CD117 Test results will be interpreted by our expert pathologists and typically fall into these categories:
- Positive Result: Indicates CD117 protein expression, commonly associated with GIST, mast cell disorders, or other CD117-positive tumors
- Negative Result: Suggests absence of CD117 expression, helping to rule out certain tumor types
- Variable Expression: Some tumors may show heterogeneous staining patterns requiring careful interpretation
It’s essential to discuss your results with your oncologist or healthcare provider, who will interpret them in the context of your complete clinical picture, including symptoms, imaging findings, and other diagnostic tests.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $76 |
| Regular Price | $112 |
Nationwide Testing Availability
GGC DNA provides comprehensive Immunohistochemistry CD117 testing services across the United States, with convenient locations in all major cities including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more. Our state-of-the-art laboratories ensure consistent, reliable results regardless of your location.
Schedule Your Test Today
Take the next step in your diagnostic journey with confidence. Our experienced team is ready to assist you with scheduling, sample collection guidance, and result interpretation. Contact us today to book your Immunohistochemistry CD117 Test and receive the precise diagnostic information you need for optimal healthcare decisions.
Call or WhatsApp: +1(267) 388-9828
Our dedicated healthcare professionals are available to answer your questions, discuss testing requirements, and help you schedule your appointment at the most convenient GGC DNA location near you.

