Immunohistochemistry BerEp4 EPCAM Test: Advanced Cancer Detection
Understanding the Immunohistochemistry BerEp4 EPCAM Test
The Immunohistochemistry BerEp4 EPCAM Test represents a cutting-edge diagnostic approach in modern pathology and oncology. This specialized test utilizes immunohistochemical staining techniques to detect the presence of epithelial cell adhesion molecule (EPCAM) using BerEp4 monoclonal antibodies. EPCAM is a transmembrane glycoprotein expressed on the surface of most epithelial cells, making it an invaluable marker for identifying epithelial-derived tissues and malignancies.
This advanced diagnostic tool plays a critical role in distinguishing between different types of cancer cells, particularly in cases where traditional histopathological examination may be inconclusive. The test’s precision and specificity make it an essential component in comprehensive cancer diagnosis and treatment planning strategies.
What the Test Measures and Detects
The Immunohistochemistry BerEp4 EPCAM Test specifically identifies and measures:
- Epithelial cell adhesion molecule (EPCAM) expression levels
- Presence of epithelial-derived cancer cells in tissue samples
- Distribution patterns of epithelial markers within tumor tissues
- Intensity and localization of BerEp4 antibody binding
This test is particularly valuable for detecting carcinomas of various origins, including lung, breast, gastrointestinal, and genitourinary cancers. It also helps differentiate between epithelial malignancies and other tumor types such as sarcomas or melanomas.
Clinical Applications and Detection Capabilities
- Identification of metastatic epithelial tumors
- Differentiation between mesothelioma and adenocarcinoma
- Detection of micrometastases in lymph nodes and other tissues
- Confirmation of epithelial origin in poorly differentiated tumors
- Assessment of tumor margins and surgical resection completeness
Who Should Consider This Test
This specialized diagnostic test is recommended for individuals experiencing:
- Unexplained tissue masses or tumors requiring precise classification
- Suspected metastatic cancer of unknown primary origin
- Previous inconclusive biopsy results requiring additional characterization
- Patients with pleural effusions or ascites of unknown etiology
- Individuals with suspected mesothelioma or other pleural malignancies
- Patients requiring differential diagnosis between epithelial and non-epithelial tumors
Symptoms and Clinical Scenarios
- Persistent cough, chest pain, or shortness of breath (suspected lung cancer)
- Unexplained weight loss, fatigue, or night sweats
- Palpable masses or lumps in any body region
- Abnormal imaging findings suggesting tumor presence
- History of cancer requiring monitoring or recurrence detection
Benefits of Taking the Immunohistochemistry BerEp4 EPCAM Test
Choosing this advanced diagnostic test provides numerous clinical advantages:
- Precise Cancer Classification: Enables accurate identification of epithelial-derived malignancies
- Improved Treatment Planning: Guides oncologists in selecting appropriate targeted therapies
- Early Detection Capability: Identifies cancer cells before they become clinically apparent
- Differential Diagnosis: Helps distinguish between different cancer types with similar presentations
- Prognostic Information: Provides insights into disease progression and potential outcomes
- Minimally Invasive Approach: Utilizes existing biopsy samples without additional procedures
Additional Clinical Advantages
- Supports personalized medicine approaches through precise tumor characterization
- Facilitates appropriate clinical trial enrollment based on specific cancer types
- Reduces diagnostic uncertainty and potential treatment delays
- Provides objective data for multidisciplinary tumor board discussions
- Enhances patient understanding of their specific cancer diagnosis
Understanding Your Test Results
Interpreting Immunohistochemistry BerEp4 EPCAM Test results requires professional medical expertise, but general guidance includes:
Positive Results Interpretation
- Strong Positive Staining: Indicates high expression of EPCAM, typically seen in epithelial carcinomas
- Focal Positive Staining: May suggest heterogeneous tumor composition or early malignancy
- Membrane Staining Pattern: Characteristic of normal EPCAM expression in epithelial cells
Negative Results Interpretation
- Complete Absence of Staining: Suggests non-epithelial origin of the tumor
- Weak or Faint Staining: May indicate poorly differentiated epithelial tumors
- Background Staining Only: Typically represents non-specific binding rather than true EPCAM expression
Clinical Correlation Importance
Your healthcare provider will correlate test results with clinical findings, imaging studies, and other laboratory tests to establish a comprehensive diagnosis. The BerEp4 EPCAM test results are one component of a complete diagnostic evaluation.
Test Pricing and Availability
| Test Component | Price (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $126 |
Turnaround Time and Sample Requirements
- Sample Collection: Daily by 6 PM
- Report Timeline: Standard tissue biopsy – 5 days | Complex tissue samples – 7 days
- Sample Type: Submit tumor tissue in 10% formal-saline OR formalin-fixed paraffin-embedded block
- Shipping Instructions: Ship at room temperature with proper documentation
Nationwide Availability and Booking Information
GGC DNA maintains comprehensive diagnostic facilities across the United States, with branches conveniently located in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art laboratories ensure consistent, high-quality testing standards nationwide.
How to Prepare for Your Test
- Provide a complete copy of your histopathology report
- Include detailed information about the biopsy site
- Share relevant clinical history and symptoms
- Ensure proper sample preservation and transportation
- Consult with your healthcare provider regarding any specific preparation requirements
Take Control of Your Health Today
Early and accurate cancer diagnosis can significantly impact treatment outcomes and quality of life. The Immunohistochemistry BerEp4 EPCAM Test provides the precise diagnostic information needed to guide effective treatment strategies. Don’t delay in obtaining the clarity you need for your healthcare journey.
Ready to schedule your test? Contact our dedicated healthcare team today:
Phone: +1(267) 388-9828
Our experienced medical professionals are available to answer your questions, discuss testing options, and help you schedule your appointment at a convenient location near you.
Take the first step toward precise diagnosis and personalized cancer care. Book your Immunohistochemistry BerEp4 EPCAM Test with GGC DNA and benefit from our commitment to excellence in diagnostic medicine.
