Immunohistochemistry Glycophorin A (GPA) Test
Comprehensive Introduction to Glycophorin A Testing
The Immunohistochemistry Glycophorin A (GPA) Test represents a cornerstone in modern hematological diagnostics, providing essential insights into erythroid lineage development and differentiation. Glycophorin A, a major transmembrane glycoprotein exclusively expressed on erythroid cells and their precursors, serves as a critical biomarker for identifying and characterizing various hematological disorders. This sophisticated immunohistochemical analysis enables precise detection of erythroid elements within bone marrow and tissue specimens, offering invaluable diagnostic information for hematologists and oncologists managing complex blood disorders.
What the Glycophorin A Test Measures and Detects
The Immunohistochemistry GPA Test specifically identifies and quantifies the presence of glycophorin A protein expression in tissue samples. This advanced diagnostic procedure detects:
- Erythroid precursor cells in bone marrow specimens
- Abnormal erythroid proliferation patterns
- Erythroleukemia and acute erythroid leukemia markers
- Myelodysplastic syndromes with erythroid predominance
- Metastatic tumors with erythroid differentiation
- Bone marrow involvement in hematological malignancies
Who Should Consider Glycophorin A Testing
This specialized test is particularly recommended for patients presenting with:
- Unexplained anemia with abnormal blood cell counts
- Suspected acute erythroid leukemia or erythroleukemia
- Myelodysplastic syndromes with erythroid hyperplasia
- Bone marrow failure syndromes requiring lineage assessment
- Patients with abnormal bone marrow biopsy findings
- Cases requiring differential diagnosis of hematological malignancies
- Monitoring treatment response in erythroid disorders
Significant Benefits of Glycophorin A Testing
Choosing the Immunohistochemistry GPA Test provides numerous clinical advantages:
- Precise Lineage Identification: Accurately distinguishes erythroid lineage cells from other hematopoietic elements
- Early Disease Detection: Enables early identification of erythroid malignancies before advanced progression
- Treatment Guidance: Provides critical information for targeted therapy selection and monitoring
- Prognostic Value: Offers valuable prognostic indicators for treatment planning and outcome prediction
- Comprehensive Assessment: Complements other hematological markers for complete diagnostic evaluation
Understanding Your Glycophorin A Test Results
Interpreting GPA test results requires professional medical expertise, but general guidance includes:
- Positive Staining: Indicates presence of erythroid lineage cells, suggesting erythroid hyperplasia or malignancy
- Negative Staining: Absence of glycophorin A expression in expected erythroid areas may indicate alternative diagnoses
- Pattern Analysis: The distribution and intensity of staining provide insights into disease severity and progression
- Clinical Correlation: Results must be interpreted in context with clinical presentation and other laboratory findings
- Follow-up Recommendations: Your hematologist will discuss appropriate next steps based on test outcomes
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunohistochemistry Glycophorin A (GPA) Test | $88 USD | $112 USD |
Nationwide Testing Availability
GGC DNA maintains comprehensive testing facilities across the United States, with specialized hematology departments in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and numerous other locations. Our network ensures accessible, high-quality diagnostic services for patients nationwide.
Schedule Your Glycophorin A Test Today
Take the crucial step toward accurate hematological diagnosis and personalized treatment planning. Our expert team of hematologists and laboratory specialists is ready to provide you with comprehensive diagnostic services and professional guidance. Contact us now to schedule your Immunohistochemistry Glycophorin A Test and receive the exceptional care you deserve.
Call or WhatsApp: +1(267) 388-9828
Our dedicated patient care coordinators are available to assist with scheduling, answer your questions, and provide detailed information about the testing process and sample requirements.

