Immunohistochemistry CD103 Test: Advanced Cancer Diagnostic Solution
Comprehensive Introduction to CD103 Testing
The Immunohistochemistry CD103 Test represents a cutting-edge diagnostic approach in modern oncology and hematology. This specialized test detects the presence of CD103, an integrin protein that serves as a crucial marker for intestinal intraepithelial lymphocytes. As a fundamental component of cancer diagnosis and treatment planning, this test provides invaluable insights into cellular behavior and immune responses within tumor microenvironments.
CD103, also known as integrin alpha E beta 7, plays a significant role in lymphocyte homing to epithelial tissues, particularly in the gastrointestinal tract. The precise detection of this marker through immunohistochemistry enables healthcare professionals to distinguish between different types of lymphocytes and understand their functional characteristics within tumor contexts.
What the CD103 Test Measures and Detects
The Immunohistochemistry CD103 Test specifically identifies and localizes the CD103 protein expression within tissue samples. This advanced diagnostic procedure measures:
- Presence and distribution of CD103-positive lymphocytes in tissue specimens
- Patterns of CD103 expression in various cell types
- Intensity and localization of CD103 staining within tumor microenvironments
- Correlation between CD103 expression and disease progression
This test utilizes highly specific antibodies that bind to CD103 antigens, creating visible staining patterns that pathologists can analyze under microscopy. The results provide critical information about the immune cell composition within tumors, particularly focusing on tissue-resident memory T cells that express CD103.
Who Should Consider the CD103 Test
The Immunohistochemistry CD103 Test is recommended for patients presenting with specific clinical scenarios and symptoms:
Primary Indications
- Patients with suspected gastrointestinal lymphomas
- Individuals with unexplained chronic diarrhea or malabsorption
- Patients undergoing evaluation for celiac disease or inflammatory bowel disease
- Cases requiring differentiation between various types of intestinal lymphocytes
- Patients with suspected enteropathy-associated T-cell lymphoma
Symptom-Based Recommendations
- Persistent abdominal pain with weight loss
- Chronic diarrhea unresponsive to conventional treatments
- Unexplained gastrointestinal bleeding
- Suspected immune-mediated gastrointestinal disorders
- Monitoring treatment response in gastrointestinal cancers
Significant Benefits of CD103 Testing
Choosing the Immunohistochemistry CD103 Test offers multiple advantages for accurate diagnosis and treatment planning:
Diagnostic Precision
- Provides definitive identification of intestinal intraepithelial lymphocytes
- Enables precise classification of lymphocyte subsets
- Supports accurate diagnosis of gastrointestinal lymphomas
- Facilitates differentiation between reactive and neoplastic processes
Clinical Management Advantages
- Guides appropriate treatment selection based on lymphocyte characterization
- Helps predict treatment response and disease prognosis
- Supports monitoring of disease progression and treatment efficacy
- Provides valuable information for targeted therapy decisions
Understanding Your Test Results
Interpreting CD103 test results requires professional medical expertise, but here’s general guidance on what your results might indicate:
Positive CD103 Expression
- Indicates presence of CD103-positive lymphocytes in the tested tissue
- Suggests involvement of tissue-resident memory T cells
- May support diagnosis of specific gastrointestinal disorders
- Helps characterize the immune microenvironment of tumors
Negative CD103 Expression
- Suggests absence or low levels of CD103-positive lymphocytes
- May indicate different lymphocyte populations or disease processes
- Could support alternative diagnoses
- Provides important exclusion criteria for certain conditions
Your healthcare provider will interpret these results in the context of your complete clinical picture, including symptoms, medical history, and other diagnostic findings.
Test Pricing and Availability
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $88 |
| Regular Price | $112 |
Nationwide Accessibility
GGC DNA maintains comprehensive testing facilities across the United States, ensuring convenient access to the Immunohistochemistry CD103 Test in all major metropolitan areas including:
- New York City and surrounding regions
- Los Angeles and Southern California
- Chicago and the Midwest
- Houston and Texas metropolitan areas
- Phoenix and Arizona regions
- Philadelphia and the Northeast
- And many additional locations nationwide
Sample Requirements and Processing
For accurate CD103 testing, please provide:
Sample Specifications
- Tumor tissue preserved in 10% formal-saline solution
- Formalin-fixed paraffin-embedded tissue blocks
- Ship samples at room temperature with proper packaging
- Include complete clinical documentation
Required Documentation
- Copy of histopathology report
- Detailed site of biopsy information
- Comprehensive clinical history
- Relevant previous test results
Turnaround Time and Reporting
GGC DNA ensures efficient processing with the following turnaround times:
- Sample Submission: Daily by 6 PM
- Block Samples: 5 days for results
- Tissue Biopsy: 5 days for results
- Large Complex Tissue: 7 days for results
Take Action for Your Health
Don’t delay essential diagnostic testing. The Immunohistochemistry CD103 Test provides critical information that can significantly impact your treatment journey and overall health outcomes. Our team of experienced hematologists, oncologists, and histology specialists is ready to provide you with accurate, reliable results.
Book your Immunohistochemistry CD103 Test today by calling our dedicated healthcare line at +1(267) 388-9828 or schedule your appointment through our online booking system. Take the first step toward precise diagnosis and effective treatment planning with GGC DNA’s advanced diagnostic services.
Our commitment to excellence in cancer diagnostics ensures you receive the highest quality testing with rapid turnaround times and comprehensive support throughout your diagnostic journey.

