Immunofixation Electrophoresis IFE 24 Hour Urine Test
Comprehensive Introduction to Immunofixation Electrophoresis
The Immunofixation Electrophoresis IFE 24 Hour Urine Test represents a cornerstone in modern hematological diagnostics, specifically designed to detect and characterize monoclonal proteins in urine specimens. This sophisticated laboratory technique combines the separation power of electrophoresis with the specificity of immunofixation, creating a powerful diagnostic tool for identifying abnormal protein patterns that may indicate serious underlying conditions.
Unlike standard urine tests that provide limited information, the 24-hour urine collection method captures the complete protein excretion pattern throughout an entire day, offering clinicians a more accurate assessment of protein dynamics. This comprehensive approach is particularly valuable for monitoring disease progression and treatment response in patients with plasma cell disorders.
What This Advanced Test Detects and Measures
The Immunofixation Electrophoresis IFE 24 Hour Urine Test specifically identifies and characterizes:
- Monoclonal immunoglobulins (M-proteins) in urine
- Bence Jones proteins (free light chains)
- Abnormal protein migration patterns
- Specific immunoglobulin classes (IgG, IgA, IgM, IgD, IgE)
- Kappa and lambda light chain types
- Quantitative protein excretion over 24 hours
This test utilizes Agarose Gel Electrophoresis followed by immunofixation with specific antibodies, allowing precise identification of monoclonal proteins that might be missed by other testing methods. The combination of these techniques provides both qualitative and semi-quantitative information essential for accurate diagnosis.
Who Should Consider This Essential Diagnostic Test
Clinical Indications and Symptoms
This test is particularly important for individuals experiencing:
- Unexplained bone pain or fractures
- Persistent fatigue and weakness
- Recurrent infections
- Unexplained kidney dysfunction
- Hypercalcemia symptoms
- Anemia without clear cause
- Elevated protein levels in routine urine tests
- Family history of plasma cell disorders
Medical Conditions Monitored
- Multiple myeloma diagnosis and monitoring
- Waldenström’s macroglobulinemia
- Monoclonal gammopathy of undetermined significance (MGUS)
- Amyloidosis assessment
- Plasma cell dyscrasias
- Response to chemotherapy monitoring
Significant Benefits of Immunofixation Electrophoresis Testing
Choosing the Immunofixation Electrophoresis IFE 24 Hour Urine Test provides numerous advantages:
- Early Detection: Identifies monoclonal proteins before symptoms become severe
- Precise Characterization: Specifically identifies immunoglobulin types and light chains
- Treatment Monitoring: Tracks disease progression and treatment effectiveness
- Comprehensive Assessment: 24-hour collection provides complete protein excretion profile
- Clinical Guidance: Helps oncologists make informed treatment decisions
- Prognostic Value: Assists in predicting disease course and outcomes
Understanding Your Test Results
Interpretation Guidelines
Your test results will provide detailed information about protein patterns in your urine:
- Normal Results: No monoclonal proteins detected; normal protein electrophoresis pattern
- Monoclonal Pattern: Presence of a distinct band indicating monoclonal protein production
- Polyclonal Pattern: Broad-based increase suggesting inflammatory conditions
- Bence Jones Proteins: Free light chains indicating plasma cell disorders
Clinical Significance
The detection of monoclonal proteins typically requires further evaluation by a hematologist or oncologist. The specific immunoglobulin type and light chain restriction provide crucial information for diagnosis and treatment planning. Regular monitoring helps assess treatment response and detect early relapse.
Test Pricing and Availability
| Test Name | Discount Price | Regular Price |
|---|---|---|
| Immunofixation Electrophoresis IFE 24 Hour Urine Test | $276 USD | $450 USD |
Testing Details
- Turnaround Time: Sample Daily by 9 am; Report 4 Working Days
- Sample Type: 20 mL (10 mL min.) aliquot of 24-hour urine without preservative
- Special Instructions: Record 24-hour volume on test request form and urine container. Ship refrigerated or frozen.
- Preparation: No special preparation required
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving patients in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing results regardless of location.
Take Action for Your Health Today
Don’t wait to get the answers you need for proper diagnosis and treatment. The Immunofixation Electrophoresis IFE 24 Hour Urine Test provides critical information that can significantly impact your healthcare journey. Our experienced team is ready to assist you with scheduling and answer any questions about the testing process.
Call or WhatsApp us today at +1(267) 388-9828 to book your test or speak with our healthcare specialists. Take the first step toward comprehensive diagnostic clarity and personalized treatment planning.

