HLA Single Antigen Bead Assay for Class I IgG Antibodies DSASAB Class I Test
Comprehensive Introduction to HLA Antibody Testing
The HLA Single Antigen Bead Assay for Class I IgG Antibodies represents a groundbreaking advancement in transplant medicine. This sophisticated diagnostic test plays a crucial role in identifying donor-specific antibodies that could potentially lead to transplant rejection. As part of our commitment to advancing transplant success rates, General Genetics Corporation offers this state-of-the-art testing to patients and healthcare providers across the United States.
Human Leukocyte Antigen (HLA) antibodies are immune proteins that recognize foreign tissue markers. When present in transplant recipients, these antibodies can target donor organs and trigger rejection episodes. The DSASAB Class I Test specifically detects IgG antibodies against HLA Class I antigens, which are critical for transplant compatibility assessment and long-term graft survival.
What This Advanced Test Measures and Detects
The HLA Single Antigen Bead Assay utilizes cutting-edge Luminex X-Map technology to precisely identify and quantify HLA Class I antibodies. This innovative approach provides:
- Detection of donor-specific HLA Class I IgG antibodies
- Comprehensive antibody profiling against multiple HLA antigens
- Quantitative measurement of antibody strength and specificity
- Identification of potentially harmful antibodies before transplantation
- Monitoring of antibody levels in sensitized patients
This test specifically targets HLA-A, HLA-B, and HLA-C locus antibodies, which are critical determinants of transplant compatibility and rejection risk assessment.
Who Should Consider This Essential Test
This specialized testing is recommended for several patient populations undergoing transplant evaluation and management:
Pre-Transplant Candidates
- Patients awaiting kidney, heart, lung, or liver transplantation
- Individuals with previous transplant history
- Patients with blood transfusion history
- Women with pregnancy history (potential sensitization)
Post-Transplant Monitoring
- Patients experiencing unexplained graft dysfunction
- Recipients with suspected antibody-mediated rejection
- Individuals undergoing immunosuppression adjustment
- Patients with declining organ function markers
High-Risk Populations
- Patients with autoimmune conditions
- Individuals with previous sensitization events
- Patients with failed previous transplants
- Those with family history of transplant complications
Significant Benefits of HLA Antibody Testing
Undergoing the HLA Single Antigen Bead Assay provides numerous advantages for transplant candidates and recipients:
- Enhanced Transplant Success: Identifies potential rejection risks before transplantation
- Personalized Treatment Plans: Guides immunosuppressive therapy decisions
- Early Intervention: Detects antibody development before clinical symptoms appear
- Improved Matching: Helps identify compatible donors and reduce wait times
- Comprehensive Monitoring: Tracks antibody levels throughout transplant journey
- Risk Stratification: Provides valuable information for transplant timing decisions
Understanding Your Test Results
Your HLA antibody test results provide critical information for your transplant team:
Negative Results
A negative result indicates no detectable HLA Class I IgG antibodies, suggesting lower immediate rejection risk. However, regular monitoring may still be recommended, especially if you have risk factors for sensitization.
Positive Results
Positive results identify specific HLA antibodies that could target donor tissue. Your transplant team will use this information to:
- Identify incompatible donors
- Plan pre-transplant desensitization protocols
- Adjust immunosuppression strategies
- Monitor antibody levels over time
Interpretation Guidance
Results are typically reported as:
- Specific antibody identification
- Antibody strength measurements
- Clinical significance assessment
- Recommendations for further testing or intervention
Always discuss your results with your nephrologist or transplant specialist for personalized interpretation and next steps.
Test Pricing and Details
| Price Type | Amount (USD) |
|---|---|
| Discount Price | $700 |
| Regular Price | $876 |
Additional Test Information
- Turnaround Time: 10-12 days
- Sample Type: 2 mL (1 mL minimum) serum from 1 SST tube
- Shipping Requirements: Refrigerated or frozen
- Pre-test Instructions: Provide brief clinical history
- Testing Methodology: Luminex X-Map technology
Nationwide Availability and Booking
General Genetics Corporation has testing facilities conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our network ensures accessible, reliable testing for transplant patients nationwide.
Take the next step in your transplant journey with confidence. Our specialized team is ready to assist you with this critical testing that could significantly impact your transplant outcomes.
Ready to Schedule Your Test?
Contact our transplant testing specialists today to schedule your HLA Single Antigen Bead Assay. Our knowledgeable staff will guide you through the process and answer any questions you may have about this essential transplant evaluation tool.
Call or WhatsApp: +1(267) 388-9828
Don’t leave your transplant success to chance. Invest in comprehensive antibody screening with our advanced HLA testing technology and take control of your transplant journey today.
