HLA Single Antigen Bead Assay for Class I & II IgG Antibodies DSASAB Class I & II Test
Comprehensive Introduction to HLA Antibody Testing
The HLA Single Antigen Bead Assay represents a groundbreaking advancement in transplant immunology, providing unprecedented precision in detecting donor-specific antibodies that could compromise transplant success. This sophisticated diagnostic tool has revolutionized how transplant teams evaluate immunological compatibility between donors and recipients, significantly improving transplant outcomes across the United States.
What This Advanced Test Measures
Our HLA Single Antigen Bead Assay utilizes cutting-edge Luminex X-Map technology to detect and quantify IgG antibodies against specific HLA Class I and Class II antigens. The test provides:
- Detailed identification of donor-specific antibodies (DSA)
- Quantitative measurement of antibody strength (MFI values)
- Comprehensive HLA Class I (HLA-A, HLA-B, HLA-C) antibody profiling
- Complete HLA Class II (HLA-DR, HLA-DQ, HLA-DP) antibody assessment
- Detection of both pre-formed and de novo antibodies
Who Should Consider This Essential Test
This advanced immunological assessment is particularly crucial for:
- Transplant Candidates: Patients awaiting kidney, heart, liver, or other organ transplants
- Previous Transplant Recipients: Individuals with history of organ transplantation
- Blood Transfusion Patients: Those with multiple transfusion histories
- Pregnant Women: With potential sensitization to paternal HLA antigens
- Sensitized Patients: Individuals with known HLA antibodies from previous exposures
Clinical Indications and Symptoms
Patients experiencing or at risk for:
- Previous transplant rejection episodes
- Unexplained graft dysfunction
- High panel reactive antibody (PRA) levels
- Multiple blood product exposures
- Pregnancy-related sensitization concerns
Significant Benefits of HLA Antibody Testing
Undergoing this comprehensive assessment provides numerous advantages:
- Improved Transplant Success: Identifies potential immunological barriers before transplantation
- Personalized Treatment: Enables tailored immunosuppression protocols
- Risk Stratification: Helps categorize patients based on immunological risk
- Donor Selection: Guides optimal donor-recipient matching decisions
- Early Intervention: Allows preemptive treatment of antibody-mediated rejection
Understanding Your Test Results
Your comprehensive report will include:
- Antibody Specificity: Detailed identification of which HLA antigens you have antibodies against
- Strength Measurement: Mean Fluorescence Intensity (MFI) values indicating antibody strength
- Clinical Interpretation: Expert analysis of the immunological significance
- Risk Assessment: Evaluation of potential transplant complications
- Management Recommendations: Guidance for your transplant team
Test Pricing and Availability
| Test Description | Price (USD) |
|---|---|
| HLA Single Antigen Bead Assay for Class I & II IgG Antibodies | Regular Price: $2126 |
| Special Discount Price | $1250 |
Sample Requirements and Processing
Sample Type: 2 mL (1 mL minimum) serum from 1 SST tube
Shipping Instructions: Ship refrigerated or frozen
Turnaround Time: 10-12 days
Pre-test Requirements: Please provide brief clinical history
Nationwide Availability Across USA
We proudly serve patients across all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, Austin, Jacksonville, Fort Worth, Columbus, Charlotte, San Francisco, Indianapolis, Seattle, Denver, Washington DC, Boston, El Paso, Nashville, Detroit, Oklahoma City, Portland, Las Vegas, Memphis, Louisville, Baltimore, and Milwaukee.
Take the Next Step Toward Transplant Success
Don’t let immunological concerns compromise your transplant journey. Our expert team of nephrologists and transplant immunology specialists are ready to provide the comprehensive testing you need for optimal transplant outcomes.
Call us today at +1(267) 388-9828 to schedule your HLA antibody assessment or book your test online through our secure patient portal.
Early detection of donor-specific antibodies can significantly improve your transplant success and long-term graft survival. Trust the leaders in transplant immunology testing to guide your journey toward better health.
