HLA Mixed Antibody Screen PRA Class I II MICA Test
Comprehensive Transplant Antibody Assessment
The HLA Mixed Antibody Screen PRA Class I II MICA Test represents a sophisticated diagnostic approach in transplantation medicine, designed to identify antibodies that could compromise transplant success. This comprehensive screening evaluates multiple antibody classes that play critical roles in organ rejection, providing transplant teams with essential data for optimal donor-recipient matching and improved patient outcomes.
What This Test Measures and Detects
Our advanced antibody screening test utilizes state-of-the-art Luminex X-Map technology to detect three crucial antibody types:
- PRA Class I Antibodies: Targets HLA-A, HLA-B, and HLA-C antigens present on all nucleated cells
- PRA Class II Antibodies: Detects antibodies against HLA-DR, HLA-DQ, and HLA-DP antigens found on antigen-presenting cells
- Anti-MICA Antibodies: Identifies antibodies against Major Histocompatibility Complex Class I-related Chain A antigens, non-HLA molecules increasingly recognized in transplant rejection
Who Should Consider This Test
This comprehensive antibody screening is essential for:
- Patients awaiting kidney, liver, heart, or pancreas transplantation
- Individuals with previous organ transplant failures
- Patients with multiple blood transfusions or pregnancy history
- Candidates for repeat transplantation procedures
- Patients with suspected antibody-mediated rejection
- Individuals undergoing desensitization protocols
Clinical Benefits and Importance
The HLA Mixed Antibody Screen provides numerous advantages for transplant candidates and their medical teams:
- Enhanced Donor Matching: Identifies specific antibodies that could lead to hyperacute or acute rejection
- Improved Transplant Success: Reduces the risk of antibody-mediated rejection through better compatibility assessment
- Comprehensive Risk Assessment: Evaluates both HLA and non-HLA antibodies for complete immunological profiling
- Personalized Treatment Planning: Enables tailored immunosuppression and desensitization strategies
- Early Intervention Opportunities: Identifies sensitized patients who may benefit from pre-transplant interventions
Understanding Your Test Results
Your test results will provide detailed information about your antibody profile:
- PRA Percentage: Indicates the percentage of potential donors against whom you have antibodies
- Specific Antibody Identification: Details which HLA antigens you have antibodies against
- MICA Antibody Status: Shows presence or absence of anti-MICA antibodies
- Clinical Interpretation: Our specialists provide clear guidance on what your results mean for your transplant journey
Test Pricing Information
| Test Name | Discount Price | Regular Price |
|---|---|---|
| HLA Mixed Antibody Screen PRA Class I II MICA Test | $300 USD | $450 USD |
Nationwide Testing Availability
We have diagnostic centers conveniently located across the United States, serving major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art facilities ensure consistent, high-quality testing standards nationwide.
Take the Next Step in Your Transplant Journey
Don’t leave your transplant success to chance. Our comprehensive HLA Mixed Antibody Screen provides the critical immunological information needed for optimal donor matching and improved transplant outcomes. Contact our transplant specialists today to schedule your test and take control of your transplant journey.
Call or WhatsApp: +1(267) 388-9828 to book your HLA Mixed Antibody Screen PRA Class I II MICA Test today!

