HLA DSA Donor Specific IgG Antibodies Class I & II Test
Comprehensive Introduction to HLA DSA Testing
The HLA DSA Donor Specific IgG Antibodies Class I & II Test represents a cornerstone in modern transplant medicine, providing essential immunological assessment for patients undergoing organ transplantation. This sophisticated diagnostic tool detects donor-specific antibodies that could potentially trigger rejection episodes, making it indispensable for transplant success and long-term graft survival.
What Does This Test Measure?
This advanced immunological assay specifically identifies IgG antibodies directed against Human Leukocyte Antigen (HLA) Class I and Class II molecules from potential organ donors. The test utilizes cutting-edge Luminex X-Map technology to provide:
- Detection of donor-specific HLA antibodies
- Quantification of antibody strength and specificity
- Identification of both Class I (HLA-A, B, C) and Class II (HLA-DR, DQ, DP) antibodies
- Assessment of immunological risk for transplant rejection
Who Should Consider HLA DSA Testing?
Primary Candidates Include:
- Patients awaiting kidney, heart, liver, or other organ transplantation
- Individuals with previous transplant history
- Patients with blood transfusions or pregnancy history
- Recipients being evaluated for living donor transplants
- Patients experiencing unexplained transplant dysfunction
Clinical Indications:
- Pre-transplant compatibility assessment
- Post-transplant monitoring for antibody-mediated rejection
- Evaluation of sensitized patients
- Assessment of immunological risk stratification
Significant Benefits of HLA DSA Testing
This comprehensive antibody screening offers multiple advantages for transplant candidates and recipients:
- Enhanced Transplant Success: Identifies potential rejection risks before transplantation
- Personalized Treatment Planning: Guides immunosuppression strategies
- Improved Patient Outcomes: Reduces incidence of antibody-mediated rejection
- Long-term Graft Survival: Supports better organ function over time
- Risk Stratification: Helps clinicians make informed decisions about transplant timing and donor selection
Understanding Your Test Results
Interpretation Guidelines:
Your HLA DSA test results will provide detailed information about antibody presence and strength:
- Negative Results: Indicate no detectable donor-specific antibodies, suggesting lower rejection risk
- Positive Results: Show presence of donor-specific antibodies requiring careful clinical evaluation
- Antibody Strength: Measured in Mean Fluorescence Intensity (MFI) values
- Clinical Correlation: Results must be interpreted by your transplant specialist in context of your medical history
Next Steps Based on Results:
- Discuss findings with your nephrologist or transplant team
- Consider additional desensitization protocols if needed
- Plan appropriate immunosuppression regimens
- Schedule follow-up testing as recommended
Test Pricing Information
| Test Description | Price (USD) |
|---|---|
| HLA DSA Donor Specific IgG Antibodies Class I & II Test – Discount Price | $326 |
| HLA DSA Donor Specific IgG Antibodies Class I & II Test – Regular Price | $450 |
Important Pre-Test Instructions
For accurate results, please follow these essential guidelines:
- Collect specimen preferably 48 hours after dialysis (when applicable)
- Provide doctor’s prescription on official letterhead with stamp
- Submit 1 photograph each of recipient and donor
- Sample types: Blood or Serum
- Turnaround time: 10-12 days
Nationwide Testing Availability
GGC DNA provides comprehensive HLA DSA testing services across the United States. We have established branches in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, and numerous other cities nationwide. Our network ensures convenient access to this critical transplant screening test regardless of your location.
Book Your HLA DSA Test Today
Take the crucial step toward successful transplantation with our comprehensive HLA DSA antibody screening. Our experienced team and advanced Luminex technology ensure accurate, reliable results you can trust for your transplant journey.
Call or WhatsApp us now at +1(267) 388-9828 to schedule your test or speak with our transplant specialists.
Don’t leave your transplant success to chance – secure your immunological assessment with GGC DNA’s premier HLA DSA testing services today.

