HLA DR4 DRB1*04 Test: Comprehensive Genetic Assessment for Autoimmune Risk
Understanding the HLA DR4 DRB1*04 Test
The HLA DR4 DRB1*04 Test represents a cutting-edge genetic analysis that examines specific human leukocyte antigen (HLA) markers crucial for immune system function. HLA molecules play a vital role in presenting antigens to immune cells, and certain variations, particularly in the HLA-DRB1*04 allele group, have been strongly associated with autoimmune disease susceptibility. This sophisticated genetic test provides valuable insights into individual predisposition to autoimmune conditions, enabling proactive healthcare management and personalized treatment strategies.
What Does the HLA DR4 DRB1*04 Test Measure?
This advanced genetic test specifically detects and analyzes the presence of HLA-DRB1*04 alleles using state-of-the-art Reverse Sequence-Specific Oligonucleotide Probe (SSOP) technology with Luminex platform detection. The test focuses on:
- Identification of HLA-DRB1*04 genetic variants
- Assessment of shared epitope sequences associated with autoimmune risk
- Detection of specific amino acid patterns linked to rheumatoid arthritis susceptibility
- Analysis of genetic markers that influence immune response regulation
Who Should Consider This Test?
Clinical Indications and Symptoms
This genetic test is particularly valuable for individuals experiencing:
- Early joint pain, stiffness, or swelling suggestive of rheumatoid arthritis
- Family history of autoimmune disorders, especially rheumatoid arthritis
- Unexplained inflammatory symptoms affecting multiple joints
- Morning stiffness lasting more than 30 minutes
- Progressive joint discomfort without clear trauma or injury
- Autoimmune conditions affecting other body systems
- Concerns about genetic predisposition to autoimmune diseases
Benefits of HLA DR4 DRB1*04 Testing
Undergoing this comprehensive genetic assessment offers numerous advantages:
- Early Risk Assessment: Identify genetic predisposition before symptom onset
- Personalized Treatment Planning: Guide medication selection and therapeutic approaches
- Family Health Insights: Understand hereditary autoimmune risk factors
- Proactive Health Management: Implement preventive strategies based on genetic profile
- Improved Diagnostic Accuracy: Complement clinical evaluation with genetic data
- Enhanced Patient Education: Empower individuals with knowledge about their genetic makeup
Understanding Your Test Results
Your HLA DR4 DRB1*04 test results will provide crucial genetic information:
- Positive for HLA-DRB1*04: Indicates increased susceptibility to rheumatoid arthritis and related autoimmune conditions. This finding suggests the presence of genetic markers associated with autoimmune disease development.
- Negative for HLA-DRB1*04: Suggests lower genetic risk for HLA-associated autoimmune disorders, though other genetic and environmental factors may still contribute to disease development.
- Interpretation Guidance: Results should be discussed with your healthcare provider in the context of your complete medical history, symptoms, and other diagnostic findings.
Test Information and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | HLA DR4 DRB1*04 Test |
| Discount Price | $150 USD |
| Regular Price | $212 USD |
| Turnaround Time | 10-12 days |
| Sample Type | 4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube |
| Shipping Instructions | Ship refrigerated. DO NOT FREEZE |
| Preparation | No special preparation required |
| Testing Method | Reverse SSOP – Luminex |
Nationwide Testing Availability
We proudly serve patients across the United States with convenient testing locations in all major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, San Jose, and many more cities. Our extensive network ensures accessible genetic testing services for patients throughout the country.
Take Control of Your Genetic Health Today
Understanding your genetic predisposition to autoimmune conditions can be a powerful step toward proactive health management. The HLA DR4 DRB1*04 Test provides valuable insights that can guide your healthcare journey and inform important medical decisions.
Ready to learn more about your genetic autoimmune risk? Contact our genetic specialists today to schedule your HLA DR4 DRB1*04 Test. Call or WhatsApp us at +1(267) 388-9828 to book your appointment and take the first step toward personalized genetic health insights.
Our experienced team is available to answer your questions, discuss testing options, and help you understand how genetic testing can benefit your specific health situation. Don’t wait to gain valuable insights into your autoimmune risk profile – schedule your test today!
