HLA-B27 Qualitative PCR Test
Understanding the HLA-B27 Test
The HLA-B27 Qualitative PCR Test represents a cutting-edge molecular diagnostic approach for detecting the presence of the HLA-B27 gene, a crucial marker in autoimmune disease diagnosis. This sophisticated test utilizes Real Time Polymerase Chain Reaction (PCR) technology to provide highly sensitive and specific results, making it an essential tool for rheumatologists and healthcare providers across the United States.
What Does the HLA-B27 Test Measure?
The HLA-B27 test specifically detects the presence of the Human Leukocyte Antigen B27 gene, which plays a significant role in the immune system’s function. This gene is part of the major histocompatibility complex (MHC) and is strongly associated with several autoimmune conditions:
- Detection of HLA-B27 gene presence through advanced PCR methodology
- Identification of genetic predisposition to autoimmune disorders
- Assessment of immune system markers related to inflammatory conditions
- Qualitative analysis providing clear positive or negative results
Who Should Consider This Test?
This test is particularly important for individuals experiencing symptoms that may indicate autoimmune conditions associated with HLA-B27. Consider scheduling this test if you experience:
- Chronic lower back pain and stiffness, especially in the morning
- Joint inflammation and swelling without apparent injury
- Eye inflammation (uveitis or iritis) with recurring episodes
- Gastrointestinal symptoms alongside joint pain
- Family history of autoimmune disorders or spondyloarthropathies
- Persistent heel pain or Achilles tendon inflammation
- Skin conditions like psoriasis with joint involvement
Clinical Benefits of HLA-B27 Testing
Undergoing the HLA-B27 Qualitative PCR Test offers numerous advantages for patients and healthcare providers:
- Early Diagnosis: Facilitates timely identification of autoimmune conditions before significant joint damage occurs
- Treatment Guidance: Helps rheumatologists develop targeted treatment plans based on genetic markers
- Disease Monitoring: Provides baseline information for tracking disease progression and treatment effectiveness
- Family Risk Assessment: Offers insights into potential genetic risks for family members
- Cost-Effective Care: Early detection can prevent costly complications and hospitalizations
Understanding Your Test Results
Interpreting HLA-B27 test results requires professional medical guidance, but here’s a general overview:
Positive Result
A positive HLA-B27 result indicates the presence of the gene, which increases susceptibility to certain autoimmune conditions. However, it’s important to note that not everyone with HLA-B27 develops autoimmune diseases. Your rheumatologist will correlate this result with clinical symptoms and other diagnostic findings.
Negative Result
A negative result suggests the absence of the HLA-B27 gene, making certain autoimmune conditions less likely. However, autoimmune diseases can still occur without this genetic marker, so clinical evaluation remains essential.
Test Details and Pricing
| Test Parameter | Details |
|---|---|
| Test Name | HLA-B27 Qualitative PCR Test |
| Discount Price | $112 USD |
| Regular Price | $176 USD |
| Turnaround Time | 10-12 Days |
| Sample Type | 3 mL (2 mL min.) whole blood from 1 Lavender Top (EDTA) tube |
| Sample Handling | Ship refrigerated. DO NOT FREEZE |
| Preparation | No special preparation required |
| Testing Method | Real Time PCR |
Nationwide Testing Availability
GGC DNA provides comprehensive HLA-B27 testing services across the United States, with convenient locations in major metropolitan areas including New York, Los Angeles, Chicago, Houston, Phoenix, Philadelphia, San Antonio, San Diego, Dallas, and San Jose. Our state-of-the-art molecular diagnostics laboratories ensure consistent, high-quality results regardless of your location.
Take Control of Your Health Today
Don’t let unexplained symptoms affect your quality of life. The HLA-B27 Qualitative PCR Test provides crucial information that can help your healthcare provider develop an effective treatment strategy. With our discounted price of only $112 USD and convenient nationwide locations, there’s no reason to delay this important diagnostic step.
Ready to schedule your test? Contact us today at +1(267) 388-9828 or book your appointment online. Our knowledgeable staff is available to answer your questions and help you take the next step toward better health management.

